About the job
Amylyx Pharmaceuticals, Inc. is a clinical-stage company in Cambridge, MA, dedicated to developing treatments for diseases with significant unmet needs. The current pipeline focuses on post-bariatric hypoglycemia (PBH), Wolfram syndrome, and amyotrophic lateral sclerosis (ALS). The team values urgency, scientific rigor, boldness, curiosity, authenticity, engagement, and accountability.
Role overview
The Senior Director of Human Resources Business Partner – Commercial will report to the SVP of Human Resources and Talent Acquisition. This leader will work closely with the Chief Commercial Officer and the Commercial Leadership Team to shape, scale, and strengthen a high-performing commercial group. The role centers on aligning HR strategies with business needs as Amylyx prepares for commercial scale-up and key data milestones.
Key responsibilities
- Advise the Chief Commercial Officer and Commercial Leadership Team to ensure HR initiatives support business objectives.
- Lead efforts to build and enhance the commercial function, supporting both corporate and field-based teams.
- Provide broad HR Business Partner support across the company, including Clinical, Technical Operations, and G&A functions as needed during the initial phase.
- Balance strategic leadership with hands-on HR work in a resource-limited and adaptive setting.
- Adapt responsibilities as the company grows, transitioning from broad HRBP support to a more specialized commercial HR leadership focus as milestones are achieved.
What success looks like
- HR strategies effectively aligned with commercial and company-wide goals.
- Strong partnerships built with commercial and cross-functional leaders.
- Ability to navigate and support a streamlined, evolving organization.
- Demonstrated flexibility and willingness to handle both strategic and operational HR responsibilities.
Location
This position is based in Cambridge, MA.
