Computational Ecologist

At OXMAN, we are revolutionizing the intersection of design, technology, and biology to create innovative products and environments on multiple scales. Our unique approach transcends traditional boundaries, allowing design to inform scientific inquiry and vice versa. In a world where human-centric design has often distanced us from the natural environment, w…

About the Role:As the Compute Engineering Lead, you will address one of our most significant challenges: enhancing performance. Our users appreciate Hex's robust platform for complex data applications, yet they seek faster execution. You will spearhead initiatives to refine our compute architecture while preserving the flexibility and power that distinguishes Hex.Leading a team of experts, you will guide our performance investments, solidify our foundational architecture, and strive towards an ambitious vision where performance becomes a competitive edge in the market.What You Will Do:Design and implement an architecture tailored for multimodal workflows, ensuring it retains the beloved features of Hex while optimizing performance across diverse data scales.Identify and analyze performance bottlenecks in detail, leading the team to consistently achieve measurable enhancements.Establish data-driven metrics to set performance targets and track progress.Deliver significant projects incrementally with seamless customer rollouts, maintaining high execution standards.Create appropriate abstraction layers that empower teams to tackle performance issues effectively with clear guarantees.Integrate compute initiatives with cross-team plans to amplify the impact of new product development.Collaborate with field teams to leverage our unique architecture as a competitive advantage.Inspire confidence across the organization in our compute strategy and clearly communicate its importance.

The City of New York is seeking a dedicated and detail-oriented Computer Associate for our Operations team. This role is crucial in ensuring the smooth functioning of our computer systems and supporting various operational needs across departments.

Role overview The City of New York seeks a Computer Systems Manager to oversee and maintain IT systems and infrastructure. This role ensures that technology supports city operations efficiently and securely, with a focus on reliability and protection of information. Key responsibilities Direct the management and ongoing improvement of IT systems and infrastructure. Collaborate with departments to align technology with organizational goals. Supervise daily operations to keep systems secure and dependable. Oversee multiple projects, managing priorities and meeting deadlines. Troubleshoot and resolve issues to enhance system performance. Requirements Background in managing computer systems and IT infrastructure. Demonstrated leadership and strong organizational abilities. Experience coordinating with various teams and stakeholders. Skilled at problem-solving and managing several projects at once. Location This position is based in New York City.

Inductive Bio is a pioneering AI medicinal chemistry partner dedicated to revolutionizing drug discovery. We create innovative virtual labs that empower drug discovery teams to make informed decisions more efficiently throughout the entire DMTA cycle. Our advanced platform features Beacon-1 ADMET prediction models, human dose projection tools, and Indy, an AI-driven medicinal chemistry assistant. In collaboration with Enamine, we provide library synthesis and direct-to-dose testing, seamlessly bridging the gap between computational design and experimental validation. Together, we fuel numerous small molecule and beyond-rule-of-five initiatives for our biotech and pharmaceutical partners.Beacon-1 has consistently excelled, securing 1st place in both the 2025 Polaris and 2026 OpenADMET-ExpansionRx blind competitions, surpassing industry giants like Merck & Co and NVIDIA, as well as EMD Serono. Our efforts have garnered $30M in funding from notable investors such as Obvious Ventures, a16z Bio + Health, and Lux Capital, in addition to being awarded $21M from the ARPA-H CATALYST program to advance next-generation toxicity models.The RoleWe are in search of an experienced computational or medicinal chemist to join our dynamic Product Science team as a Product Scientist. In this pivotal role, you will be the primary scientific liaison for partner projects, leveraging your expertise in medicinal chemistry, computational chemistry, and DMPK to tackle complex molecular optimization challenges with an emphasis on dose-centric solutions. You will engage with a diverse array of small molecule modalities, therapeutic areas, and modeling obstacles.As a thought leader in the evolution of Inductive's platform, you will contribute to the enhancement of our predictive models and dose projection tools, as well as Indy, our AI medicinal chemistry assistant, drawing from your own experiences and insights gained from real-world partner programs. We seek an individual whose instincts regarding small molecule optimization are honed through extensive hands-on experience, and who is eager to utilize these instincts to shape products that empower drug discovery teams.Your Responsibilities:Partner-Facing ScienceCultivate and manage the scientific relationships with partner project teams across various modalities, including reversible and covalent small molecules, macrocycles, molecular glues, and heterobifunctionals.Organize and clarify complex program data. Analyze structure-activity relationships (SAR), discern the insights provided by the data, and proactively address inconsistencies before they lead to detrimental decisions.Steer medicinal chemistry strategies: determine what to synthesize, what to test, how to prioritize compounds for further development, and where to allocate synthetic resources. Identify potential liabilities early in the process and assist partners in constructing risk mitigation plans.

Join OXMAN, a pioneering nature-based research and design firm located in the heart of Manhattan, where we are dedicated to transforming the connection between humanity and the environment. Our multidisciplinary approach spans architecture, ecology, materials science, and computation, enabling us to craft innovative, nature-centric solutions to pressing environmental issues.EDENAt OXMAN, we recognize the essential services that nature provides for human survival—such as carbon sequestration, water filtration, and air production. Through our initiative EDEN, we aim to enhance and regenerate these natural processes by fostering biodiverse and resilient ecosystems that support all forms of life.EDEN serves as a digital design environment for engineering and designing ecosystems, adeptly modeling the complex flows, relationships, and processes that sustain them. We develop tools that measure how landscapes can be engineered to achieve specific performance targets—whether that’s cooling urban areas, filtering water, sequestering carbon, or safeguarding vital species. These tools are instrumental in guiding the creation of ecologically vibrant sites.A single hectare of expertly designed landscape can absorb up to four times the annual emissions of an average home, filter enough water for thirteen neighborhoods, and lower ambient temperatures by over ten degrees. EDEN empowers designers to plan purposefully for these outcomes through analysis, simulation, and optimization, effectively translating ecological functionality into actionable design metrics.Our design team collaborates closely with clients on site-specific objectives, ranging from logistics hubs and residential developments to rewilding projects and climate-resilient initiatives. Together, we are crafting biodiverse and productive environments that benefit both humanity and nature.Role OverviewOXMAN is on the lookout for a talented Computational Designer to join the EDEN design team. This role focuses on developing procedural design workflows that incorporate ecological intelligence into architectural, landscape, and planning projects.Situated at the crossroads of design, data, and simulation, the ideal candidate will be proficient in Houdini workflows, utilizing procedural systems to investigate, analyze, and visualize intricate spatial relationships. We seek a creative thinker with a systems-oriented mindset and meticulous attention to detail—capable of converting ecological and environmental data into dynamic, rule-based geometries that drive practical design choices.

Role Overview The City of New York is hiring an entry-level Computer Associate (Software) to help build and maintain software applications for city operations. This role supports essential services and contributes to technology that serves New Yorkers every day. What You Will Do Develop and maintain software tools used across city departments Work alongside a team focused on improving city services through technology Support ongoing projects that impact daily life in New York City Location Position based in New York City.

Role Overview Sigma Computing is hiring a Commercial Account Executive in New York City. This role focuses on building strong sales pipelines, bringing in new customers, and directly contributing to company growth. What You Will Do Develop and manage sales opportunities from prospecting through close Secure new business and expand Sigma's customer base Support the company's growth by meeting and exceeding sales goals Work Location This position is based in New York City. Remote work is not available for this role.

Join Normal Computing and Shape the Future of TechnologyAt Normal Computing, we develop pioneering software and hardware solutions that drive innovation in the semiconductor industry, bolster critical AI infrastructure, and enhance the interconnected systems that power our modern world. Our collaborative team spans across major cities including New York, San Francisco, Copenhagen, Seoul, and London.Your Impact:As a Forward-Deployed Product Manager (FDPM), you will be at the cutting edge of Normal's product development. You will work closely with our key semiconductor partners, ensuring the success of Normal's products within their operations. This role encompasses the entire journey—from identifying initial use cases to facilitating widespread adoption and influencing the future of Normal’s product offerings. The solutions you create will reach every Normal customer globally.Your collaboration will extend to senior leadership teams of the world’s most influential companies, allowing you to operate with significant autonomy, backed by Normal’s extensive resources and relationships.You are adept at engaging with diverse stakeholders, from strategic conversations with senior executives to detailed discussions with engineers. Having successfully launched products that achieved tangible adoption and outcomes, you are driven to expand your impact on more significant challenges at a larger scale.Key Responsibilities:Lead product initiatives for our essential customers. Own product success throughout the engagement lifecycle—from initial discovery to large-scale production adoption—ensuring the Normal EDA platform becomes integral to chip design processes and generates measurable results.Act as a trusted advisor. Cultivate trust within our customer organizations—not merely as a vendor, but as a key partner who comprehends their business needs deeply to build tailored solutions. You will articulate and deliver the product vision for Normal within their context.Drive opportunity identification. Approach each engagement with insightful perspectives rather than just questions. Analyze customer operations, pinpoint where Normal EDA can significantly enhance outcomes, and convert those insights into actionable product hypotheses. Define new use cases and collaborate closely with our engineering team to materialize validated hypotheses into functional product features.Influence Normal’s product roadmap. Transform customer insights into structured product directions and priorities. Differentiate between unique constraints and systemic opportunities, directly influencing how Normal EDA evolves to meet market demands.

Ignite Your Passion for Education!Are you prepared to shape the future of education? At Zeta, we are dedicated to delivering an exceptional blend of academic excellence and social-emotional growth for our students. We believe that every child deserves a world-class education that nurtures a lifelong enthusiasm for learning. Our mission is to transform public education in New York City and beyond.Join Us in Our JourneyWe are excited to announce the launch of our inaugural Zeta High School class for 9th graders in the 2026-27 academic year, located at 1080 St. Nicholas Avenue in Upper Manhattan. This landmark initiative represents our commitment to providing superior education from pre-kindergarten through high school. With multiple elementary and middle schools already thriving across the Bronx, Upper Manhattan, and Queens, we plan to establish 1-2 new schools annually to ensure that every child has access to excellent and equitable education. Become a part of our expanding team and be a catalyst for positive change in the lives of students.Discover Our Innovative ModelLearn more about Zeta's groundbreaking high school approach by clicking HERE.

Role Overview Sigma Computing is growing quickly, and the Technical Support Engineering team is scaling to meet the needs of a larger global user base. This team recently earned the 2024 Stevie Gold Award for Customer Service. As a Technical Support Engineer based in New York City, the work centers on helping customers solve technical, business, and data challenges using the Sigma platform. The role involves close collaboration with Product, Engineering, and Go-to-Market teams to troubleshoot complex issues, deliver solutions, and improve both the product and support experience. What You Will Do Work directly with Sigma customers and pre-sales staff to identify and resolve complex technical problems. Partner with the development team to define best practices and build tools for diagnosing issues and improving service performance. Coordinate with teams across backend, frontend, DevOps, design, product management, and marketing to support a strong user experience. Join quarterly projects, provide periodic on-call support, and take on assignments that focus on automation and process improvements.

Join Normal Computing - Pioneering the Future of TechnologyAt Normal Computing, we are at the forefront of technological innovation, developing essential software and hardware solutions that propel the semiconductor industry, AI infrastructure, and the systems that sustain our world. Our collaborative team spans across major cities such as New York, San Francisco, Copenhagen, Seoul, and London.Your Impact:As a Hardware Engineer specializing in Design Verification, you will play a crucial role in our Verification AI team. This position blends verification expertise with product shaping, enabling you to validate internal hardware, specifically Physics-inspired ASICs, while optimizing the data generated by our AI. You will be instrumental in connecting raw verification data to our Machine Learning models, ensuring our AI benefits from high-quality, curated data.

Role Overview Sigma Computing is building the next generation of data interaction. The platform lets users explore billions of data rows in seconds, work with data in a familiar spreadsheet-like interface, and build visualizations, applications, and workflows. Sigma is now expanding these capabilities with AI to help users create, discover insights, and make decisions faster. The Senior AI/ML Engineer will join a team focused on developing the AI infrastructure that shapes Sigma’s future. Work here directly impacts how enterprises use Sigma in their daily operations. Location This position is based in New York City, NY.

About Sigma Computing Sigma Computing builds a cloud-native analytics and business intelligence platform. The product helps business users explore and share insights from cloud data warehouses, all without writing SQL. Sigma serves industry leaders and is backed by prominent investors. Role Overview The Director of Strategic Partnerships will lead and grow Sigma's collaboration with Snowflake, a key partner. This senior role shapes joint go-to-market efforts, drives co-selling, and builds revenue through the partnership. This position is based on-site in New York City and reports to the Senior Director of Partnerships. What You Will Do Set and execute the overall strategy for the Snowflake partnership, including priorities, focus areas, and go-to-market plans. Own business outcomes related to the Snowflake partnership, with responsibility for partner-attributed and partner-influenced pipeline and revenue. Design and scale co-selling programs that grow demand and deliver measurable revenue. Lead joint business planning with Snowflake: run quarterly strategy sessions, build execution plans, and coordinate executive reviews. Align Sigma sales teams with Snowflake account representatives through enablement, playbooks, and active deal support. Act as the main escalation point for Snowflake-related deal strategies, executive connections, and partner conflict resolution. Build and maintain strong relationships with Snowflake’s Partner, Sales, and Field Leadership, influencing sales activity during live deals. Drive collaboration across Sales, Marketing, Enablement, and Operations to put Snowflake partnership initiatives into practice. Work with Marketing to coordinate joint campaigns, events, and programs that support co-selling and pipeline goals. Track and analyze partnership performance metrics to refine strategy and improve results. What Sigma Is Looking For The ideal candidate brings deep credibility within the Snowflake ecosystem, thinks like a general manager, and can turn strategy into practical action. Strong stakeholder management skills are essential, from executive leaders to account teams, as well as the ability to align internal teams across Sales, Marketing, Enablement, and Partnerships.

About Genesis Molecular AIGenesis Molecular AI integrates advanced molecular machine learning with robust physics principles to unearth innovative small molecule therapies for serious health conditions. Our cutting-edge molecular AI platform, GEMS, utilizes generative models alongside high-throughput molecular simulations to navigate chemical space and prioritize compounds with unparalleled speed and precision.About the TeamOur computational chemistry group collaborates closely with machine learning researchers, medicinal chemists, and biologists to transform our computational models into viable drug candidates for our internal projects and pharmaceutical partners.You will be part of a team guided by seasoned drug discovery experts and method developers specializing in statistical mechanics, free energy methodologies, and computer-aided drug design.About the RoleWe seek a binding free energy specialist who possesses both the theoretical acumen to propose innovative methodological concepts and the programming skills essential for their execution. This role will advance free energy methodologies across our platform and oversee their implementation.You will be the go-to expert for our teams requiring physics-based rankings of high-affinity binders, particularly in potency ranges where existing models begin to plateau. Your contributions will significantly influence our compound selection process, determining which molecules progress in development and expediting our discovery of optimal therapies for patients.This position is not simply about executing established processes. A deep understanding of theoretical frameworks and a hands-on approach to developing and deploying tools is crucial.What You Will Do:Lead the binding free energy functionAssume responsibility for small molecule binding free energy calculations that directly impact project decisions.Establish best practice protocols across various programs, refining them as the platform evolves.Enhance and optimize existing methodsRefine current methods and codebases (e.g., FEP, TI, and associated alchemical/free energy workflows).

Join Normal Computing – Where Innovation Meets OpportunityThe Normal team is at the forefront of building foundational software and hardware solutions that propel technology forward, serving critical sectors such as the semiconductor industry and AI infrastructure. Our collaborative efforts span across major cities including New York, San Francisco, Copenhagen, Seoul, and London.Your Contribution to Our Vision:As a Software Engineer specializing in backend product engineering within Normal EDA, your primary responsibility will be developing systems and workflows that empower hardware engineers in the creation and verification of chips vital to modern AI technologies. Experience in the semiconductor or hardware sectors is advantageous but not mandatory.In this role, you will encounter complex technical challenges at the convergence of AI and product engineering. You will be tasked with designing solutions and implementing incremental improvements to deliver new features effectively. You will take ownership of APIs and schemas that are crucial for core product functionalities, collaborating closely with fellow engineers to enhance these systems.We are seeking engineers who are enthusiastic about tackling real-world challenges in intricate technical domains and creating systems that enable users to maximize their productivity. If you are driven to design reliable, high-performance systems and craft intuitive user experiences for AI-driven workflows, this position offers a unique opportunity to make a significant impact in the industry.

Join Normal Computing for Incredible Opportunities!At Normal Computing, we are passionate about building the software and hardware that drive technological innovation. Our efforts support the semiconductor industry, critical AI infrastructure, and the extensive systems that empower our world. With teams spread across New York, San Francisco, Copenhagen, Seoul, and London, we collaborate as one unified team.Your Role in Our Mission:We are seeking a talented AI Research Engineer to pioneer advancements in agentic LLMs and reinforcement learning for our innovative code generation tool, Nectar. In this role, you will design and conduct experiments, develop agents, curate datasets from intricate technical documents, and establish rigorous evaluation methods. You will write production-level research code and work closely with engineering teams to deliver enhancements to our clients. While leadership experience is not a prerequisite, your research and development impact will be significant.Key Responsibilities:Design and implement multi-agent and reinforcement learning strategies for agentic code generation and tool usage.Develop research prototypes that integrate with Nectar; collaborate to transition successful prototypes into production.Create comprehensive evaluation frameworks, including task specifications, pass/fail criteria, coverage metrics, and dashboards for cost and latency.Gather and curate datasets from a variety of sources, including PDFs, logs, and tables; generate synthetic data where necessary, and maintain data documentation and licensing.Conduct disciplined analyses of experiments through systematic ablations; document findings and decisions.Keep abreast of recent developments in LLM agents, reinforcement learning (both offline and online, including RLHF/RLAIF), constrained decoding, and program synthesis.Qualifications:PhD in Computer Science, Artificial Intelligence, or Machine Learning (or equivalent research experience), with publications preferably in multi-agent reinforcement learning, agentic AI, or reinforcement learning for language and code.Proficient in Python and machine learning frameworks, with a preference for PyTorch; experience with JAX or Hugging Face is a plus.Proven track record of translating research into functional systems; a strong emphasis on reproducibility (tests, seeds, configurations, logging).Experience in designing evaluation harnesses and success metrics for sequential and agentic tasks.Adept at data acquisition and curation from various document types; possess strong instincts regarding data quality and licensing.Bonus Qualifications:Research experience in program synthesis, code generation, constrained decoding, or execution-based rewards.

Role Overview Sigma Computing builds a high-performance platform that integrates with modern data architectures. As the team grows in New York City, the company seeks a Senior Fullstack Software Engineer who enjoys solving complex technical problems and shaping features that make data accessible for a wide range of users. The engineering group values collaboration and a shared mission to improve how organizations use data. What You Will Do Work on challenging problems to deliver an interactive, high-performance analytics experience on top of modern data warehouses. Develop software using tools and languages such as Rust, Go, GraphQL, TypeScript, and Slate. Create new algorithms and techniques to improve performance and interactivity for analytics and workflow solutions, supporting some of the largest enterprises. Diagnose and resolve product or system issues by analyzing, tracking, and debugging problems. Design and implement new features to meet the needs of a growing user base. Collaborate with teams across infrastructure, design, product management, customer support, sales, and marketing to build new product capabilities.

About the Role Sigma Computing builds a high-performance platform designed for modern data architecture. As the team grows in New York City, the company is looking for engineers who enjoy solving complex problems and want to help make data accessible to everyone. The engineering group values collaboration and a focus on delivering solutions that matter across the technology stack. What You Will Do Take on challenging problems to create interactive experiences for data exploration and analysis within data warehouses. Work with technologies including Rust, Go, GraphQL, Node, and Kubernetes. Build backend distributed services, develop algorithms, and design APIs that power Sigma Computing's cloud applications. Investigate and resolve product or system issues by diagnosing root causes and debugging as needed. Design and implement new features to support a rapidly expanding user base. Participate in design and code reviews with peers and stakeholders to maintain high engineering standards and best practices.

Role Overview The Strategic Commercial Account Executive at Sigma Computing holds a key position in driving the company’s growth. This role focuses on building relationships with senior stakeholders, navigating complex enterprise organizations, and securing agreements that deliver strong results for both clients and Sigma. Location and Work Environment This position is based in New York City. It is not remote, plan to work in the office four days a week alongside experienced colleagues. Sigma’s office culture values presence, collaboration, and decisive action. The environment is high-energy and rewards strong performance. What You Will Do Engage with high-level decision makers at commercial and enterprise accounts Develop and manage relationships that lead to significant business agreements Work closely with industry leaders to influence decisions and close impactful deals Contribute to Sigma’s rapid annual growth (over 80%) by driving new business Participate in local travel within New York and across the East Coast (about 25% of the time) for in-person meetings with prospects, customers, and partners What Success Looks Like Consistently closing transformative deals Building a strong network within enterprise organizations Gaining hands-on experience in sales strategy, negotiation, and relationship management Contributing to a collaborative and ambitious team culture