Principal Scientist - Downstream Process Development (Contract)

Adverum Biotechnologies is hiring a contract Principal Scientist focused on Downstream Process Development. This role is based onsite in Redwood City, CA and supports gene therapy programs by advancing and optimizing downstream processes. Key responsibilities Design and improve downstream process strategies for gene therapy initiatives. Work closely with col…

Adverum Biotechnologies, Inc. is seeking a passionate and detail-oriented Process Development Scientist to join our innovative team on a contract basis. In this role, you will be responsible for developing and optimizing processes for the production of gene therapies. You will collaborate with cross-functional teams to ensure the successful transition of processes from development to clinical manufacturing.

We are seeking an experienced and driven Senior Scientist in Downstream Process Development to join our dynamic team on a contract basis. In this role, you will be responsible for developing and optimizing downstream processes for biologics production, focusing on purification and formulation. Your expertise will play a crucial role in advancing our innovative therapies to improve patient outcomes.

Adverum Biotechnologies, Inc. is seeking a talented and motivated Technical Development Scientist to join our dynamic team on a contract basis. In this role, you will contribute to the development and optimization of innovative gene therapies aimed at treating serious ocular diseases. Your expertise will play a critical role in advancing our cutting-edge projects and ensuring the success of our therapeutic candidates.

Join our innovative team at Adverum Biotechnologies, Inc. as a Clinical Scientist/Senior on a contract basis. You will play a pivotal role in designing and implementing clinical trials, analyzing data, and collaborating with cross-functional teams to advance our gene therapy products. Your expertise will contribute to impactful research that aims to transform patient care and improve outcomes.

Join Revolution Medicines as a Senior Scientist I in Analytical Development, where you will play a pivotal role in advancing our innovative therapeutics. This position offers an exciting opportunity to contribute to the development of cutting-edge analytical methods and techniques that are crucial for our drug development pipeline. You will collaborate with cross-functional teams to ensure the successful delivery of high-quality data and analytical support.

Revolution Medicines is seeking a highly motivated and experienced Senior Scientist I for our Clinical Biomarker Development team. In this pivotal role, you will be responsible for the design, execution, and interpretation of biomarker studies aimed at supporting clinical trials. You will work closely with cross-functional teams to advance our innovative therapies and contribute to our mission of transforming the lives of patients with cancer.

Revolution Medicines is seeking a talented and motivated Senior Scientist I to join our Clinical Biomarker Development team. In this role, you will contribute to the advancement of innovative therapies by developing and validating biomarkers that support clinical decision-making. You will have the opportunity to work in a collaborative environment, leveraging cutting-edge technologies and methodologies to drive impactful results.

Revolution Medicines is seeking a highly skilled Senior Corporate Counsel to lead our contracting efforts in the realm of clinical development. In this pivotal role, you will provide strategic legal support and guidance on a variety of clinical contracts, including clinical trial agreements, vendor contracts, and collaboration agreements. You will work closely with cross-functional teams to ensure that all legal aspects align with our business objectives and regulatory requirements.

Join Team CATHEXIS, where we transform the government contracting landscape through swift responses, extensive expertise, and innovative problem-solving. Our foundational strengths lie in superior program and project management, data analytics, and audit services—all anchored by our commitment to operational excellence.We recognize and respect the hard work you’ve put into your career, and we strive to make each day better than the last. At CATHEXIS, we embrace an all-in mindset, collaboratively fostering an environment that upholds our shared values while supporting individual aspirations. Our core values include Respect, Engagement, Customer Service, Integrity, Teamwork, and Excellence. We believe that success flourishes when we listen empathetically, uphold ethical standards, and create a fun, rewarding environment where everyone’s strengths are celebrated.We are seeking a passionate Data Scientist / Machine Learning Engineer to enrich our team. In this role, you will collaborate directly with data scientists, software engineers, and subject matter experts to define new analytical capabilities that empower our federal clients in their decision-making and digital transformation journeys.Note: We are actively building a pipeline of qualified candidates for future opportunities. If your qualifications match our anticipated needs, a member of our Talent Acquisition team may reach out when a relevant role becomes available or for preliminary discussions.

Join Revolution Medicines as a Scientist II, specializing in drug product development. In this critical role, you will leverage your scientific expertise to contribute to innovative drug formulation and delivery systems. Collaborate with a talented team dedicated to advancing groundbreaking therapies that improve patients' lives.

Join Poshmark, a leading social commerce platform, as a Staff Data Scientist. In this pivotal role, you will leverage your expertise in data analysis and machine learning to drive insights and innovations that enhance our platform and user experience. You'll work collaboratively with cross-functional teams to develop robust models, implement data-driven strategies, and contribute to the evolution of our analytics capabilities.

At Retro, we are pioneering innovative therapies that target age-related diseases. Our focus is on cellular reprogramming and autophagy to restore cell and tissue vitality, aiming to add a decade to the healthy human lifespan.We are assembling a passionate, mission-driven team of talented individuals who thrive in our dynamic startup environment characterized by rapid innovation, transparency, and adaptability.We are on the lookout for an ambitious Scientist specializing in Genomics to develop and optimize platforms that facilitate the discovery of therapies aimed at rejuvenating cellular and tissue functions. You will manage sequencing workflows from start to finish, collaborating closely with automation and computational scientists to scale your innovations and generate crucial data for our advanced models.

Join Adverum Biotechnologies, Inc. as a Senior Scientist specializing in Drug Product development. In this pivotal role, you will leverage your expertise in pharmaceutical sciences to contribute to our mission of advancing innovative gene therapies. You will collaborate closely with cross-functional teams to drive the formulation and development of high-quality drug products, ensuring compliance with regulatory standards and industry best practices.

Revolution Medicines, Inc. seeks a Safety Scientist based in Redwood City, California. This role centers on supporting the safety and effectiveness of therapies under development. The Safety Scientist works with colleagues from various disciplines to review safety data, conduct evaluations, and assist with regulatory filings. What you will do Work with internal teams to assess and monitor safety profiles of therapies in development. Analyze safety data from both clinical and preclinical studies. Help prepare documents needed for regulatory submissions. Role impact This position plays a part in shaping new therapies and influencing the future of medicine by ensuring careful safety evaluation and strong collaboration across teams.

Revolution Medicines develops targeted therapies for patients with RAS-addicted cancers. The company’s pipeline includes several RAS(ON) inhibitors currently in clinical development, such as Daraxonrasib (RMC-6236), Elironrasib (RMC-6291), Zoldonrasib (RMC-9805), and RMC-5127. The team is dedicated to advancing treatments for cancers driven by mutations in the RAS signaling pathway. Role overview The Senior Safety Scientist will join the Global Patient Safety Science group, supporting pharmacovigilance and safety science activities across both early and late-stage clinical programs. This position covers the full portfolio of Revolution Medicines’ investigational therapies. Key responsibilities Oversee safety for clinical studies, including reviewing and authoring protocols, Investigator's Brochures (IBs), Informed Consent Forms (ICFs), and Development Safety Update Reports (DSURs). Conduct medical review of individual case safety reports (ICSRs) and monitor safety surveillance for assigned products. Proactively perform medical safety surveillance during clinical trials to identify and address safety issues. Prepare and present safety data summaries to internal and external stakeholders. Engage in risk management activities, including routine safety data analysis, medical review of ICSRs, and literature review. Share knowledge on drug class safety issues and competitor landscape. Identify potential clinical safety concerns and recommend risk mitigation strategies. Contribute to preparation and maintenance of clinical trial protocols, IBs (including reference safety information), ICFs, DSURs, Risk Management Plans (RMPs), Core Content Development Summaries (CCDS), and product labeling. Review clinical protocols, IBs, ICFs, and related documents to ensure alignment with safety strategies. Location This role is based in Redwood City, California, United States.

Join N-Power Medicine, where we are revolutionizing drug development by reimagining the clinical trial process. Our mission is to enhance the integration of clinical practice and ensure that physicians and patients participate more fully in clinical research. We are building a dynamic, multi-disciplinary team that embodies our core values of community empowerment through generosity, curiosity, and humility. Our urgent goal is to deliver advanced therapies to patients more rapidly.We are currently seeking a motivated Clinical Data Scientist to take ownership of the final stage of our clinical data pipeline. You will play a critical role in transforming intricate datasets from manual abstraction, AI models, and electronic sources into high-quality, analysis-ready deliverables for our pharmaceutical partners. This position is at the crossroads of data science and clinical research, requiring proficiency in data cleaning, transformation, and statistical programming (R, Python, SQL) to create comprehensive reports while ensuring data integrity, accuracy, and compliance with regulatory standards.The ideal candidate will work collaboratively with Clinical Operations, AI Engineers, and Data teams to validate outputs, automate workflows, and enhance our data infrastructure, all while maintaining stringent documentation and adhering to privacy regulations. Proficiency in a Posit development environment and familiarity with GitHub and Jira are essential; experience with Databricks and AI development tools is a plus.This role is perfect for a detail-oriented, technically adept professional with 2-5+ years of experience in clinical data science or related fields, eager to contribute to the acceleration of drug development within a mission-driven and rapidly growing environment.

Join us at Retro, a pioneering leader in the field of regenerative medicine, as we seek a dedicated Scientist specializing in iPSC Differentiation with a focus on Hematopoiesis. In this role, you will harness your expertise to drive innovative research and contribute to our mission of advancing human health through cutting-edge science.

Join our innovative team at Integrated Resources, Inc. as a Data Scientist / Computational Biologist. In this role, you will leverage your scientific expertise and analytical skills to drive data-driven solutions in the field of biology. Collaborating with cross-functional teams, you will analyze complex biological data, develop predictive models, and contribute to groundbreaking research.

Revolution Medicines is a pioneering clinical oncology enterprise focused on developing innovative targeted therapies for patients battling RAS-addicted cancers. Our research and development pipeline includes advanced RAS(ON) inhibitors aimed at inhibiting various oncogenic RAS protein variants. Our lead candidates currently in clinical trials include daraxonrasib (RMC-6236), a multi-selective RAS(ON) inhibitor; elironrasib (RMC-6291), a selective inhibitor for RAS(ON) G12C; zoldonrasib (RMC-9805), targeting RAS(ON) G12D; and RMC-5127, aimed at RAS(ON) G12V. As part of our dedicated team, you will collaborate with exceptional professionals committed to advancing treatment options for patients with mutations in the RAS signaling pathway.The Opportunity:We invite applications from passionate structural biologists eager to contribute to multiple oncology therapeutic programs. The ideal candidate will possess substantial hands-on experience in sample preparation, data acquisition, and analysis through X-ray crystallography and cryo-EM. You will leverage your expertise to form compound-driven complexes and optimize crystallization and CryoEM conditions, aiming to uncover high-resolution structural data that will enhance small molecule design and mechanistic insights. We are looking for a collaborative team player who thrives in an interdisciplinary environment, driving the development of cutting-edge oncology therapeutics.Responsibilities:Design and execute experiments to elucidate small molecule-driven multi-protein complex structures through CryoEM and X-ray crystallography.Conduct cryo-EM grid screening, optimization, data collection, and refinement to facilitate high-quality structure determination.Collaborate with interdisciplinary teams, including chemists, computational chemists, biologists, project teams, and management, effectively communicating structural data within the broader context of drug discovery.Maintain meticulous records and facilitate clear communication among internal and external stakeholders.Demonstrate a strong desire for innovation in a dynamic, fast-paced environment, working collaboratively with diverse colleagues across the organization.