Senior Applications Engineer jobs in San Francisco – Browse 6,716 openings on RoboApply Jobs

Senior Applications Engineer jobs in San Francisco

Open roles matching “Senior Applications Engineer” with location signals for San Francisco. 6,716 active listings on RoboApply Jobs.

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companyBrex logo
Full-time|$192K/yr - $240K/yr|On-site|San Francisco, California, United States

Why Join Brex?Brex is an innovative AI-driven spend management platform designed to empower businesses to manage expenses with confidence. We provide integrated corporate cards, banking solutions, and global payment options, alongside intuitive software for travel and expense management. From startups to large enterprises, clients like DoorDash, Flexport, and Compass leverage Brex to optimize spending, lower costs, and enhance efficiency worldwide.Joining Brex means embracing challenges, pushing boundaries, and collaborating with industry leaders. We are dedicated to fostering a diverse and inclusive culture where your potential is only limited by your aspirations. We equip you with the necessary tools, resources, and support to advance your career.Engineering at BrexOur engineering culture focuses on building scalable systems with intention and speed. Our teams, spanning Software, Data, Security, and IT, work with high autonomy and deep collaboration. We confront challenging technical problems, take ownership of outcomes, and strive for excellence across all levels—from architecture to deployment. Here, engineering is regarded as a craft, and builders evolve into leaders.Your RoleAs a Senior Application Security Engineer, you will be pivotal in identifying and addressing security vulnerabilities within the Brex platform. Your responsibilities will include conducting code and design reviews, penetration testing, and managing vulnerabilities. You will also develop and maintain tools for static and dynamic testing of the platform, ensuring secure developer workflows. You will collaborate closely with teams across Security Operations, GRC, Product Security, Front End Platform, and IT Infrastructure.We seek individuals with a robust background in penetration testing and a proven track record of uncovering vulnerabilities in complex systems. Your ability to craft exploits that highlight business risk will be essential. This role demands a collaborative spirit, as you will engage with various engineering teams throughout Brex. Your enthusiasm for diverse perspectives and needs is crucial as we build world-class financial services with top-tier security.Brex is at the forefront of AI-driven financial services for dynamic companies such as Coinbase, Robinhood, and Anthropic. As we integrate AI across our product suite, this role will have the chance to significantly influence our approach.

Feb 19, 2026
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company
Full-time|On-site|Cosmic HQ

Join Our Team as a Senior Applications EngineerLocation: San Francisco, CA (full-time, in-person)Company OverviewAt Cosmic Robotics, we are dedicated to transforming the construction of essential infrastructure on Earth while innovating technologies that will empower humanity to construct beyond our planet. Our flagship technology, Cosmic-1, revolutionizes solar panel installation, achieving speeds ten times faster than current methodologies, aiding our transition to a sustainable energy future and setting the stage for autonomous construction.The RoleAs a Senior Applications Engineer, you will serve as the vital link between our state-of-the-art robotics and our clientele. You will oversee the complete deployment cycle and ensure the long-term success of our robots in real-world applications. Collaborating closely with customers, you will be instrumental in developing, deploying, and optimizing the world’s leading construction robots. Your role is essential in enhancing our platform through customer-driven feature development and fostering widespread adoption. As a pivotal member of our team, you will contribute to defining the future of autonomous construction.This position offers a unique chance to:Tackle significant challenges that will shape the future of infrastructure and energy.Collaborate with an exceptional team hailing from NASA, SpaceX, Google, Built Robotics, and other industry leaders.Accelerate your personal growth and leadership capabilities within a rapidly expanding company.ResponsibilitiesManage the entire lifecycle of robot deployment at customer locations, encompassing initial setup, commissioning, field validation, and ongoing maintenance.Act as a technical partner to customers, converting their operational requirements into actionable features for our robots and platform.Design, integrate, and launch new features tailored to meet specific customer needs.Diagnose and resolve field issues while ensuring maximum robot uptime.Establish project milestones, strategize roadmaps, and meet ambitious timelines for deployments and feature enhancements.Recruit, nurture, and cultivate a world-class engineering team.

Dec 3, 2025
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companyema logo
Full-time|Remote|San Francisco Bay Area

Join ema as a Senior AI Applications Engineer and play a pivotal role in developing cutting-edge AI solutions. You will collaborate with cross-functional teams to design, implement, and optimize AI applications that address real-world challenges. Bring your expertise in machine learning and software development to help us drive innovation and enhance user experiences.

Mar 26, 2026
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companyPlaid Inc. logo
Full-time|On-site|San Francisco

Join Plaid as a Senior Software Engineer specializing in AI Applications, where you'll be at the forefront of technology, working on innovative solutions that redefine how businesses connect with financial services. In this role, you will design, develop, and deploy cutting-edge AI applications that enhance user experiences and streamline operations.

Feb 27, 2026
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companyCity and County of San Francisco logo
Full-time|On-site|San Francisco

Join the City and County of San Francisco as a Senior Information Systems Engineer specializing in applications. This pivotal role involves collaborating with multiple departments citywide to enhance our technological landscape. You will leverage your expertise in information systems to develop, implement, and maintain innovative solutions that drive efficiency and effectiveness across our operations.

Nov 6, 2023
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companyChime logo
Full-time|Remote|Remote, USA; San Francisco, CA, USA

Join Chime as a Senior Application Security Engineer and play a pivotal role in safeguarding our applications and systems from security threats. In this fully remote position, you will collaborate with cross-functional teams to implement security best practices, conduct code reviews, and ensure compliance with industry standards.Your expertise will help shape our security posture as you design and execute vulnerability assessments and penetration tests. If you are passionate about security and want to make a meaningful impact, we want to hear from you!

Mar 16, 2026
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companySentry logo
Full-time|$190K/yr - $280K/yr|Hybrid|San Francisco, California

About SentryAt Sentry, we are dedicated to eradicating bad software. Our mission is to empower developers to create better software more efficiently, allowing everyone to enjoy technology once more.With over $217 million in funding and a community of more than 100,000 organizations, including industry leaders like Disney, Microsoft, and Atlassian, we are at the forefront of building performance and error monitoring tools that minimize bug fixing and maximize product development.We embrace a hybrid work model across our global teams, designating Mondays, Tuesdays, and Thursdays as in-office days to foster collaboration. If you are passionate about creating tools that enhance the digital experience, join us in developing the next generation of software monitoring solutions.About The RoleOur security team is committed to safeguarding every aspect of Sentry, from our customer data to our internal code. As a Senior Security Engineer, you will be integral to our mission of enhancing security across our application and Kubernetes platform. Collaborating with engineering teams, you will help strengthen Sentry’s cloud security posture through strategic architecture, threat modeling, and hands-on coding when necessary.Key ResponsibilitiesLead critical initiatives aimed at addressing significant security challenges, from conceptualization to execution.Collaborate on cross-departmental objectives to drive security goals forward.Conduct research and assess new technologies that can bolster our security framework with a focus on scalability.Identify vulnerabilities within our systems and data while developing and implementing robust protective measures.Support cross-functional teams in integrating security solutions that adhere to Secure-by-Design principles.Ideal Candidate AttributesDesire to be a foundational member of an agile, engineering-centric security team.Enjoy collaborating with enthusiastic security, application, platform, and infrastructure engineers eager to innovate.Passionate about advancing security practices to enhance software quality.

Feb 6, 2026
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companyLightning AI logo
Full-time|On-site|San Francisco, California, United States; Seattle, Washington, United States

Join Lightning AI as a Senior Application Security Engineer specializing in the realms of Artificial Intelligence and Machine Learning. In this pivotal role, you'll be responsible for enhancing our application security posture across our innovative platforms. Collaborate with a team of talented engineers to identify vulnerabilities, implement security best practices, and ensure our AI-driven solutions remain robust and secure.

Apr 1, 2026
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companyCloudflare, Inc. logo
Full-time|Hybrid|Hybrid

Join Cloudflare as a Senior Systems Engineer specializing in Cloud Application Control, where your expertise will shape the future of cloud security. You will be responsible for designing, implementing, and optimizing our systems that protect users and applications worldwide. This role requires a deep understanding of cloud technologies, networking, and security protocols.

Mar 4, 2026
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companyZeta Global logo
Full-time|$160K/yr - $200K/yr|On-site|San Francisco, California, United States

WHO WE ARE Zeta Global (NYSE: ZETA) is a cutting-edge AI-Powered Marketing Cloud that utilizes advanced artificial intelligence and vast consumer insights to enhance the efficiency with which marketers acquire, nurture, and retain customers. Our mission, through the Zeta Marketing Platform (ZMP), is to simplify sophisticated marketing by integrating identity, intelligence, and omnichannel activation into a single, powerful platform—backed by one of the industry's largest proprietary databases and AI technology. We empower our enterprise clients across diverse sectors to create personalized consumer experiences, driving superior outcomes for their marketing strategies. Founded in 2007 by David A. Steinberg and John Sculley, Zeta Global is headquartered in New York City, with a global presence. Discover more at www.zetaglobal.com. About the Role We are seeking a highly experienced Staff Application Security Engineer to spearhead our application and platform security efforts. You will be tasked with embedding robust security measures throughout the development lifecycle—from threat modeling to deployment—ensuring that secure-by-design principles are consistently upheld. Operating at a significant scale, Zeta supports billions of consumer profiles and handles petabytes of data within our real-time, AI-driven marketing frameworks. In this pivotal role, you will safeguard our high-performance systems by promoting best practices, assessing emerging threats, and enabling cross-functional teams to develop secure and reliable applications. This high-impact position offers significant visibility across engineering, product, and executive leadership teams. Key Responsibilities Threat Modeling & Security Validation Lead threat modeling and security architecture reviews for distributed, event-driven systems. Integrate security code reviews, SAST/DAST, Software Composition Analysis (SCA), and container scanning into CI/CD and AI/ML pipelines. Coordinate and oversee incident simulations specific to AI systems; manage red/blue team exercises to validate our defensive posture. Conduct security evaluations of third-party vendors and tools to ensure compliance with our security standards.

Mar 19, 2026
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company
Full-time|On-site|San Francisco Bay Area

Merge Labs stands at the forefront of research, dedicated to integrating biological and artificial intelligence to enhance human capabilities, autonomy, and experiences. Our innovative approach focuses on developing groundbreaking brain-computer interfaces that operate at high bandwidth, seamlessly integrate with advanced AI technologies, and ensure safety and accessibility for all users.About Our TeamOur Core Software team at Merge is instrumental in constructing the software infrastructure that will empower the next wave of neuroscience. We are tasked with designing, implementing, and maintaining systems that transform experimental data into actionable insights—reliably, reproducibly, and on a large scale. Our audience includes biologists, clinicians, neuroscientists, and machine learning researchers. Our objective is clear: to create secure and efficient systems that accelerate scientific progress. As trusted partners in science, we uphold the highest software integrity standards, establish data collection and analysis interfaces, and democratize scientific data access across our organization.Position OverviewIn the role of Senior Application Engineer, you will be a pivotal member of our team, responsible for defining and developing the core application utilized by scientists, clinicians, and collaborators to interact with our specialized multi-modal hardware product. Collaborating closely with our hardware team, you will explore the possibilities, design intuitive user interfaces for clinicians, and craft efficient tools for our research scientists. This position, which reports to the Head of Software, is highly collaborative, engaging with data engineers to leverage our cutting-edge data platform and offer low-code and no-code solutions for complex laboratory workflows. You will cater to a diverse user base—from hardware engineers needing flexible, high-performance APIs to external research partners requiring user-friendly interfaces with built-in safeguards. A meticulous approach and a commitment to ethical software development are essential, as every user interaction must exemplify the highest standards of scientific practice.Key ResponsibilitiesDevelop software solutions enabling scientists to create tailored 3+1D treatment plans that combine functional ultrasound imaging with targeted ultrasound neuromodulation.Integrate ultrasound, microscopy, gantry, and other automation APIs into a cohesive application for executing both unique experiments and high-throughput screening.Collaborate with cross-functional teams to ensure alignment of technical solutions with user needs and safety standards.

Dec 11, 2025
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companymercor logo
Full-time|On-site|San Francisco

About the Role mercor is hiring an Application Security Engineer in San Francisco. This role focuses on protecting our applications by applying proactive security practices and conducting detailed assessments. The work centers on finding vulnerabilities and putting strong security protocols in place to keep our products secure and dependable.

Apr 16, 2026
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companyunitxlabs logo
Full-time|On-site|HQ

As a Field Application Engineer at unitxlabs, you will play a pivotal role in bridging the gap between our innovative technology solutions and our valued clients. Your expertise will empower customers to maximize the potential of our products, ensuring they achieve their goals effectively. You will be responsible for providing technical support, conducting product demonstrations, and driving customer satisfaction through exceptional service.

Apr 10, 2026
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companyHayden AI logo
Full-time|On-site|San Francisco HQ Office

Join Our Mission at Hayden AIAt Hayden AI, we strive to leverage cutting-edge computer vision technology to revolutionize how transit systems and government agencies tackle real-world challenges.Our innovative mobile perception system is designed to enhance transit efficiency, improve street safety, and foster a sustainable future through various applications, including bus lane enforcement and transportation optimization technologies.Your RoleAs a pivotal member of the Hayden Software Engineering team, you will help develop our next-generation Automated Bus Lane Enforcement product. You will be engaged in creating, integrating, and deploying edge-based perception models.This position is centered around C++ software engineering. You will be responsible for delivering high-quality, modern C++ (C++17/20) code that operates on embedded Linux edge devices, primarily utilizing the NVIDIA Embedded Platform.Your work will involve building and optimizing real-time CV/ML pipelines on-device, incorporating CUDA/TensorRT and efficient camera/video input/output.You will collaborate closely with Product Management to translate customer requirements into effective software solutions.Being part of a startup, you will thrive in a fast-paced, dynamic environment with evolving challenges.As we expand, your contributions will help establish a robust foundation through well-designed and thoroughly tested code that can be shared across the organization.

Jul 28, 2025
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companyDiscord Inc. logo
Full-time|$248K/yr - $279K/yr|On-site|San Francisco Bay Area

At Discord, we connect over 200 million users every month through our platform, primarily for one exhilarating reason: gaming. With more than 90% of our community engaged in gaming, they collectively spend an astounding 1.5 billion hours indulging in thousands of unique titles on Discord each month. Our commitment is to enhance the gaming experience, making it more enjoyable for everyone to communicate and socialize before, during, and after gameplay.Your RoleLead a talented team of security engineers to develop and implement robust application security tools and services, conduct secure design reviews, and perform threat modeling, while providing expert guidance on secure development practices at Discord.Ensure the security of our code and development processes from the Integrated Development Environment (IDE) through to production.Enhance the detection and remediation of security vulnerabilities at scale.Collaborate with various Discord teams to minimize security risks for our users while proactively identifying and addressing security bugs prior to production deployment.Partner with Discord’s product engineering and management teams to advocate for innovative security features that enhance user protection.

Mar 4, 2026
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companyGeneralist logo
Full-time|On-site|San Francisco Bay Area (San Mateo) or Boston (Somerville)

About the RoleAs a Software Engineer, you will play a pivotal role in developing applications utilized by customers, deployment partners, researchers, and various internal teams to diagnose, educate, and perform quality assurance on our robotic systems.This position involves cutting-edge full-stack web and API engineering in a rapidly evolving AI-driven landscape.Your Responsibilities Will Include:Designing and implementing external and internal API interfaces for seamless interaction with Generalist systems.Creating tools and workflows that support and expedite the core objectives of researchers, engineers, and operations teams across the organization.Developing the primary web application used by researchers, operations, and deployment teams to assess and train robotic models.You May Excel in This Position If You:Possess a strong intuition for crafting exceptional user interfaces and experiences.Have a solid understanding of modern web stack technologies, including Typescript, React, FastAPI, Postgres, and AWS.Know how to effectively manage and utilize contemporary AI coding agents to enhance development speed while ensuring high production quality.

Feb 12, 2026
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companyOpenAI logo
Full-time|Hybrid|San Francisco

About Our TeamAt OpenAI, we are driven by a profound mission: to ensure that Artificial General Intelligence (AGI) is beneficial to all of humanity. Our commitment to this mission extends to the B2B sector, where we aim to empower businesses, enterprises, and governments to transform their operations, fostering economic growth and enhancing human potential.We develop and manage innovative products that bridge our groundbreaking research with millions of companies and developers globally. Our technology powers the OpenAI API and various enterprise solutions, enabling users worldwide to enhance their productivity and efficiency. Our diverse teams, specializing in product engineering, backend infrastructure, and safety, collaborate to deliver OpenAI's technology with utmost reliability, security, and an exceptional user experience.About the RoleWe are seeking talented Frontend Engineers to design and implement user interfaces that make advanced AI intuitive and accessible. In this role, you will collaborate closely with design, product management, and research teams to create responsive, high-performance, and secure web applications that bring OpenAI’s models and enterprise products to life.This position is based in either San Francisco, CA, or New York City, NY. We operate on a hybrid work model, requiring 3 days in the office each week, and we offer relocation assistance to new hires.Your ResponsibilitiesDevelop and maintain scalable web applications utilizing modern JavaScript/TypeScript, React, and accompanying technologies.Create reusable UI components and front-end frameworks to expedite product development.Enhance client performance while ensuring cross-browser and device accessibility.Collaborate with designers to craft user-friendly and visually appealing interfaces.Participate actively in end-to-end product planning and strategic decision-making.You Will Excel in This Role If You:Possess 5+ years of professional experience (excluding internships) in building production-grade web applications.Are proficient in TypeScript/JavaScript, React, and contemporary web development tools.Demonstrate a strong commitment to design fidelity, performance, and accessibility standards.Enjoy rapid iteration to deliver polished, user-centric features.Previous experience as a founder or early engineer at a startup is a plus.

Dec 19, 2025
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companyHarness, Inc. logo
Full-time|On-site|San Francisco, California, United States

Harness is a pioneering AI Software Delivery Platform company, founded by the visionary technologist and entrepreneur Jyoti Bansal, the mind behind AppDynamics, which was acquired by Cisco for an astounding $3.7 billion. With approximately $570 million in funding and a current valuation of $5.5 billion, Harness is supported by prominent investors such as Goldman Sachs, Menlo Ventures, IVP, Unusual Ventures, and Citi Ventures. In an era where AI is rapidly transforming code creation, the true challenge lies in the subsequent stages: testing, deployments, application security, reliability, compliance, and cost optimization. Harness addresses this challenge by integrating AI and automation into the software delivery lifecycle, allowing teams to deliver software more quickly while ensuring robust security and governance throughout all stages.Utilizing Harness AI and the Software Delivery Knowledge Graph, our platform injects deep context and intelligent automation into every aspect of the software delivery process, embedding governance and policy-driven controls throughout.In the past year alone, Harness has facilitated over 185 million deployments, 82 million builds, 18 trillion flag evaluations, 8 million security scans, and optimized 9.1 billion tests, while safeguarding 3 trillion API calls and managing $2.8 billion in cloud expenditure. This has empowered esteemed clients like United Airlines, Morningstar, and Choice Hotels to enhance release speeds by up to 75%, cut cloud expenses by as much as 60%, and achieve a tenfold increase in DevOps efficiency.With a diverse global team operating across 14 offices in 25 countries, Harness is at the forefront of the future of AI-driven software delivery and is eager to attract exceptional talent to propel us forward.

Mar 25, 2026
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companymercor logo
Full-time|On-site|San Francisco or NYC

About the Role mercor is hiring a Security Engineer focused on Application Security in San Francisco or New York City. This role centers on protecting company applications from threats and vulnerabilities. The Security Engineer works closely with teams across the company to strengthen security practices and improve the overall security of our software. What You Will Do Work with engineers and other teams to apply security best practices throughout the development lifecycle Perform detailed security assessments of applications Identify and address new and existing security risks Help improve the security posture of mercor’s applications

Apr 15, 2026
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companyCloudflare, Inc. logo
Full-time|Hybrid|Hybrid

Join Cloudflare as a Senior Technical Support Engineer specializing in Application Performance. In this pivotal role, you will be responsible for providing expert support and guidance to our customers, ensuring optimal performance of their applications. You will work closely with cross-functional teams to troubleshoot and resolve complex issues, enhancing our customers' experience and ensuring their success.

Feb 13, 2026

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