Biomedical AI Research Engineer

About Xaira TherapeuticsXaira Therapeutics is a pioneering biotechnology startup committed to harnessing the power of artificial intelligence to revolutionize the processes of drug discovery and development. The company is at the forefront of creating generative AI models designed to develop protein and antibody therapeutics, paving the way for effective tre…

About Xaira TherapeuticsXaira Therapeutics is a cutting-edge biotechnology startup dedicated to harnessing the power of artificial intelligence to revolutionize the fields of drug discovery and development. Our mission is to innovate generative AI models that facilitate the design of protein and antibody therapeutics, paving the way for effective treatments against traditionally challenging molecular targets. In addition, we are advancing foundational biological models to enhance target identification and patient stratification. These pioneering technologies are designed to continuously uncover novel therapies and boost the success rates in drug development. Our headquarters are strategically located in the San Francisco Bay Area, Seattle, and London.About the RoleWe are seeking an AI Scientist to become an integral part of our team at the convergence of machine learning and single-cell biology. In this pivotal role, you will focus on the development and application of foundational models to large-scale perturb-seq and single-cell datasets, revealing new biological mechanisms and therapeutic potentials. You will be responsible for designing scalable machine learning architectures that can extract insights from high-dimensional perturbation data and integrate across multi-omic modalities.

About Xaira TherapeuticsXaira Therapeutics is a pioneering biotech startup dedicated to harnessing the power of artificial intelligence to revolutionize drug discovery and development. Our innovative team is at the forefront of creating generative AI models that facilitate the design of protein and antibody therapeutics, enabling the development of medications targeting historically challenging molecular entities. We are also working on foundational models that enhance our understanding of biology and disease, leading to improved target identification and patient stratification. Together, these advancements strive to continuously uncover novel therapies and enhance the efficiency of drug development processes. Headquartered in the vibrant tech hubs of the San Francisco Bay Area, Seattle, and London, Xaira is positioned to make a global impact in healthcare.About the RoleWe are on the lookout for a skilled AI Research Engineer to join our dynamic team. As an integral member of our interdisciplinary unit, you will work closely with AI scientists, engineers, and drug discovery specialists to develop and implement AI models aimed at expediting the discovery and development of innovative therapeutics. This position presents an exciting opportunity to apply state-of-the-art AI methodologies in practical settings to tackle critical healthcare challenges and contribute to enhancing global health outcomes.We seek candidates with a proven track record in building and deploying machine learning systems in industrial contexts, emphasizing rigor, scalability, and cross-functional collaboration. The ideal candidate will possess experience in transforming research concepts into robust, production-ready applications that deliver measurable results.

About PhyloPhylo is a pioneering applied research laboratory dedicated to the advancement of agentic intelligence aimed at accelerating the discovery process for biomedical scientists. We envision a future where AI agents revolutionize biomedical research, fostering rapid and systematic scientific advancements.Our expanding team consists of elite researchers and engineers specializing in AI and biology. With a robust $13.5M seed funding round led by top-tier investors such as a16z, Menlo Ventures, and Anthropic, and endorsed by Nobel Prize winners and leading biologists, Phylo is at the forefront of developing next-generation AI systems for the life sciences.About the RoleWe are seeking a skilled engineer to construct and maintain the essential systems that drive Phylo’s agentic AI platform in live environments. You will architect and implement distributed systems, computing frameworks, and service architectures that ensure our AI agents operate reliably at scale, whether in cloud-native settings or enterprise environments.This position represents a foundational role within our team, granting you substantial ownership over critical infrastructure decisions, a high level of autonomy, and the opportunity to significantly influence the company’s trajectory from day one.Our engineering team is AI-driven, leveraging coding agents extensively, moving swiftly, and maintaining rigorous standards of engineering excellence.ResponsibilitiesDesign and develop production systems that orchestrate agent execution and support AI-driven scientific workloads.Construct and manage scalable, reliable infrastructure across cloud, hybrid, and on-premises enterprise environments.Oversee enterprise deployment architecture, ensuring secure, reproducible installations for customer-managed infrastructures (VPC, private cloud, on-prem, air-gapped, or regulated environments).Create systems for sandboxed execution, secure task isolation, and controlled computing environments. Design and implement foundational security, access control, and compliance mechanisms suitable for enterprise deployments.Collaborate closely with ML and scientific teams to convert computational workflows into robust, production-grade distributed systems.RequirementsA minimum of 3 years of industry experience in backend, infrastructure, or distributed systems engineering.Demonstrated proficiency in at least one programming language (e.g., Python, Go, Rust).

About PhyloPhylo is a pioneering applied research laboratory dedicated to harnessing agentic intelligence, revolutionizing the discovery process for biomedical scientists. We envision a future where AI agents transform the landscape of biomedical research. Our rapidly expanding team comprises skilled researchers and engineers specializing in AI and biology.About the RoleWe are seeking a Product Engineer to enhance and scale the foundational product experiences of Phylo's AI agent platform. This multifaceted, full-stack position leans towards frontend development and aims to convert cutting-edge agentic research into fast, reliable, and enjoyable products utilized by real scientists.You will take ownership of product features from start to finish — encompassing UI and interaction design, backend APIs, billing, authentication, and integrations. Collaborating closely with AI researchers, scientists, and infrastructure engineers, you will deliver production-grade systems promptly while maintaining high standards of quality.This role demands a deep interdisciplinary approach. You will spend significant time listening, questioning, and facilitating communication between scientists, product managers, engineering teams, and AI research. As an AI-native engineering team, we leverage coding agents extensively, operate at a fast pace, and uphold a rigorous standard of engineering excellence.Key ResponsibilitiesDevelop and manage full-stack product features across the Phylo platform, from user-facing UI to backend services.Design and implement frontend-heavy experiences for engaging with AI agents, workflows, and scientific tools.Oversee essential product components such as billing, usage tracking, authentication, permissions, and account management.Collaborate intimately with scientists, AI researchers, and engineers to translate capabilities into user-friendly, production-ready product features.Deliver swiftly, iterate based on user feedback, and continuously enhance product quality, reliability, and performance.RequirementsA minimum of 2 years of industry experience as a product, full-stack, or frontend-focused software engineer.Extensive experience in developing modern web applications (e.g., React, TypeScript, or similar frameworks).Proficient in working across the technology stack (frontend, backend, and infrastructure) with excellent communication skills to collaborate effectively across biology, product, engineering, and AI teams.Demonstrated product instincts — a strong passion for user experience, attention to detail, and understanding of how real users interact with products.

About Xaira TherapeuticsXaira Therapeutics is a pioneering biotech startup dedicated to harnessing the power of artificial intelligence to revolutionize drug discovery and development. Our mission is to advance the frontier of generative AI models which design innovative protein and antibody therapeutics, making strides against previously difficult molecular targets. Additionally, we are committed to creating foundational models for biology and disease, enhancing target identification and patient stratification. Through these cutting-edge technologies, we aim to consistently unveil novel therapies and elevate the success rates in drug development. Headquartered in the dynamic San Francisco Bay Area, with additional offices in Seattle and London, we are at the forefront of biotech innovation.AI in ResidenceThe AI in Residence program is a highly selective opportunity designed for those at the forefront of machine learning and drug discovery. This role serves as an industry alternative to a traditional postdoctoral position, tailored for exceptional researchers and engineers eager to apply advanced AI methodologies to real-world biomedical challenges, encompassing the entire process from data handling to system deployment.As a resident, you will join a small, focused cohort engaged in high-impact AI projects throughout Xaira. You will closely collaborate with AI scientists, research engineers, and drug discovery teams to conceptualize, develop, and deliver machine learning capabilities that directly impact therapeutic programs. This role demands hands-on, system-level work with tangible scientific implications.We seek candidates who possess technical expertise, intellectual independence, robust research judgment, and a proven track record of high-quality deliverables, whether through publications, contributions to open-source projects, or production systems.

About PhyloPhylo is an innovative applied research lab dedicated to developing intelligent agents that enhance the speed and effectiveness of biomedical discovery. Our mission is to revolutionize biomedical research through advanced AI technologies. We proudly host a rapidly expanding team of researchers and engineers specializing in both AI and biological sciences.About the RoleHaving recently launched publicly with a $13.5M seed round led by Andreessen Horowitz and Menlo Ventures/Anthropic, Phylo is on the cutting edge of the biotech landscape. Our enterprise inbound interest is robust, with active deployments and a growing list of pharmaceutical and biotech clients utilizing Biomni Lab. We are seeking a talented individual to convert this momentum into a sustainable commercial engine.As one of our inaugural commercial hires, you will have a unique opportunity to architect the Go-To-Market (GTM) strategy from the ground up, promoting a product that possesses a distinct technical advantage at the intersection of AI and biology. You will take charge of the entire enterprise sales cycle—from initial outreach and discovery to proposal design and closing deals—while serving as a solution architect who can effectively engage in pharmaceutical R&D discussions, comprehend scientific nuances, and deliver impactful proposals. Collaborating directly with our CEO, founding team, and scientific experts, you will play a pivotal role in defining Phylo's market entry approach.What You'll Work OnManage biotech and pharmaceutical accounts comprehensively, overseeing outreach, discovery, proposal crafting, pilot programs, and closure.Act as a solution architect: identify customer challenges, collaborate with our technical team to create customized solutions, and deliver compelling presentations.Devise outbound strategies aimed at specific applications, such as target discovery, indication expansion, and literature-scale analysis.Establish strong relationships within the biopharma ecosystem, engaging with R&D leaders, computational biology teams, and data and tool partners.Facilitate co-marketing initiatives, integration efforts, and distribution partnerships with collaborators in the ecosystem.Contribute to shaping the GTM strategy, including aspects like pricing, packaging, segmentation, and customer retention, as we build our commercial function from scratch.

About Us:Calico Life Sciences LLC, a pioneering research and development firm established by Alphabet, is dedicated to exploring advanced technologies and model systems that deepen our understanding of the biological mechanisms governing human aging. Our mission is to leverage this knowledge to create interventions that promote longer and healthier lives. With a state-of-the-art technology lab and a commitment to curiosity-driven scientific inquiry, Calico, in partnership with academic and industry leaders, is a vibrant nexus for medical innovation and drug development.Position Overview:We are on the lookout for a passionate and seasoned Principal Investigator in Cardiovascular Research to spearhead laboratory studies and drug development initiatives focused on cardiovascular diseases associated with aging. This pivotal role encompasses the design and execution of research strategies aimed at identifying and validating novel drug targets for age-related cardiovascular conditions. The ideal candidate will possess a robust background in cardiovascular biology, aging research, target identification and validation, and drug discovery methodologies. Proficiency in both in vivo and in vitro models of cardiovascular disease and aging is highly advantageous. This position presents a unique opportunity to directly influence the development of therapeutics designed to enhance cardiovascular healthspan.

About Us:Calico Life Sciences LLC, a forward-thinking research and development company established by Alphabet, is dedicated to unraveling the complexities of human aging through innovative technologies and model systems. Our mission is to deepen understanding of the biology underlying aging, enabling us to create interventions that promote longer, healthier lives. Our state-of-the-art laboratories, commitment to groundbreaking discovery science, and robust pipeline of drug development in collaboration with academic and industry partners, make Calico an inspiring environment for driving medical advancements.Role Overview:We are on the lookout for a dynamic and experienced Director of Research to oversee our early discovery research team comprising talented Principal Investigators and their lab teams. This pivotal role will involve shaping research strategies, assessing research outcomes, and propelling our early-stage drug discovery initiatives aimed at enhancing healthspan through the development of new therapies for aging and age-related conditions. We are particularly interested in candidates with expertise in advanced biochemical, molecular, and cellular biological methodologies, including but not limited to microscopy and omics technologies, to dissect the intricacies of aging biology. A strong background in transitioning projects from early discovery to translational drug development is essential.Join our collaborative and cross-disciplinary team at the forefront of aging research, partner with world-class technology laboratories, spearhead ambitious research initiatives that redefine our understanding of aging, and innovate therapeutics for aging and age-associated diseases.

Join Veracyte, a leader in transforming cancer care through innovative diagnostics that empower patients and clinicians alike. At Veracyte, we provide an inspiring work environment where you can make a significant impact on patients' lives while advancing your career. Our culture, known as the Veracyte way, emphasizes collaboration, resilience, and a commitment to excellence.Our Core Values:We Seek A Better Way: We boldly innovate and learn from challenges to improve cancer care.We Make It Happen: We prioritize urgency, quality, and enjoyment in our work.We Are Stronger Together: We foster open collaboration and celebrate our collective successes.We Care Deeply: We honor our diverse backgrounds and support each other in doing what is right.The Role:We are on the lookout for an enthusiastic Bioinformatics Research Scientist to join our Translational Bioinformatics group within the Bioinformatics and Data Science Team. This pivotal role involves leveraging computational and statistical techniques on extensive transcriptomic and genomic datasets, particularly focusing on prostate cancer biology and its clinical implications. The ideal candidate will play a key role in identifying clinically relevant molecular signatures that enhance disease stratification, prognosis, and the development of diagnostics, while effectively communicating findings to both scientific and clinical audiences. This position offers a unique opportunity to bridge the realms of data science, biology, and clinical research through close collaboration with scientists, clinicians, and cross-functional teams to convert complex data into actionable insights.

Join Veracyte, a pioneering leader in genomic diagnostics, as a Clinical Research Associate. In this dynamic role, you will be integral to the design, execution, and management of clinical trials. Your expertise will help drive the development of innovative tests that enhance patient care.

Join Veracyte, a pioneering diagnostics company that is transforming patient care through innovative genomic testing. As a Research Scientist I in our Sustaining team, you will play a crucial role in optimizing our existing assays and ensuring our products maintain the highest standards of quality and performance. This position offers the opportunity to work in a collaborative environment where scientific discovery meets practical application.

Join Our Vision at insitroinsitro is on the hunt for a dynamic Senior Director of External Research & Development to spearhead all facets of our external R&D portfolio. This pivotal leadership role is accountable for crafting and executing the company’s external R&D strategy, defining and optimizing our collaborations with preclinical and research contract research organizations (CROs).In this strategic capacity, you will work closely with senior leaders across diverse functions, including Research, Drug Discovery, Technical Operations, Corporate Development & Strategy, Finance, and Project Management, ensuring a seamless approach to alliance and outsourcing management.Reporting directly to the Chief Technical Operations Officer, this position welcomes both remote and local candidates, offering flexibility to work onsite (3 days per week) at our South San Francisco office or a hybrid model (~1 week per month) with some travel (up to 25%) to oversee partnerships both domestically and internationally.Key ResponsibilitiesExternal R&D Strategy: Drive a comprehensive external research strategy, aligning with corporate objectives and supporting the research portfolio. Represent insitro in senior-level partnership discussions and negotiations, ensuring effective management of business partnerships.Partner Network Management: Cultivate and oversee innovative relationships with a strategic network of high-quality CROs and external partners, maintaining the highest scientific and ethical standards.Project Execution & Oversight: Ensure the successful planning, monitoring, and execution of externally sourced projects across the vendor network, adhering to project goals, budgets, and timelines. Foster strong communication and partnership with internal stakeholders.Governance & Compliance: Develop effective governance models and collaborate with Legal and Procurement on partner selection, negotiations, and agreement execution.Process & Team Leadership: Lead a team to implement industry-leading processes in vendor management, ensuring compliance with contractual obligations and standard operating procedures (SOPs).Operational Review & Improvement: Regularly assess the overall scope of outsourced services to ensure resource efficiency and effectiveness.

Join our dynamic team as a Scientist I and contribute to groundbreaking research that drives innovation in the field. You will be an integral part of our scientific community, focusing on developing solutions that enhance our understanding of complex biological systems.

Location: South San Francisco, CA, United StatesJob Identification: 2223Job Schedule: Full timeResponsibilitiesAssist in conducting research experiments under the guidance of a Scientist.Perform laboratory experiments to support the development and optimization of products, services, and technologies, from feasibility studies to application testing and stability assessments.Develop methodologies and prepare Standard Operating Procedures (SOPs) as necessary.Acquire chemicals, materials, and reagents for experiments.Handle and prepare chemicals and biochemical reagents for experimental procedures.Ensure proper disposal of chemical and biological waste, maintaining accurate records as required.Calibrate and maintain scientific instruments and laboratory equipment.Keep organized, detailed, and precise records of all experimental processes and data.Conduct data analysis using tools such as Excel, Tableau, flow cytometry, and image analysis.Deliver project status updates and reports.Review relevant literature and apply advanced knowledge to enhance research outcomes.QualificationsBachelor's degree or higher in Biology, Chemistry, or a related scientific field, with 0-10 years of experience in a research setting (preferably at least 3 years).Experience in conducting experiments involving Next Generation Sequencing (NGS), RT-qPCR, fluorescence spectroscopy, biomolecule conjugation, immunoassays, data analysis, and image analysis.Proven ability to effectively plan, execute, analyze, and document research experiments.Skilled in the operation and maintenance of instruments for chemical and spectroscopic analysis, including fluorescence spectroscopy, flow cytometry, and UV-VIS.Highly organized, adaptable, and capable of multitasking in a fast-paced environment with strict timelines.Excellent attention to detail in making experimental observations.Proficient pipetting skills are required.Familiarity with liquid handling systems is preferred, but not mandatory.Strong verbal and written communication skills are essential, as the role requires frequent updates, reports, technical meetings, and presentations.#LI-LP1About UsMyriad Genetics Inc. is a pioneering company in personalized medicine, committed to transforming patient lives globally through innovative molecular diagnostics. We discover and commercialize tests that assess disease risk, diagnose conditions, evaluate disease progression, and inform treatment decisions across six key medical specialties. Our strategic focus is on maintaining leadership in molecular diagnostics while improving patient care and reducing healthcare costs.

About Us Calico Life Sciences LLC, founded by Alphabet, is at the forefront of groundbreaking research and development aimed at unraveling the complexities of human aging. Our mission is to utilize cutting-edge technologies and innovative model systems to deepen our understanding of biological mechanisms governing aging. By leveraging this knowledge, we aim to develop interventions that empower individuals to live longer, healthier lives. Our state-of-the-art labs, commitment to scientific discovery, and collaborative efforts with academic and industry partners form a dynamic environment conducive to significant medical breakthroughs. The Calico Postdoctoral Fellowship Program We invite passionate early-career scientists to join our quest to expand the understanding of aging biology. This fellowship presents a rare chance to excel in aging research, enhance scientific training, and foster research independence. The Postdoctoral Fellowship is a fixed-term academic position lasting three years, with the potential for a one-year extension. Fellows become integral members of Calico's labs and community. This program is meticulously designed to cultivate independent investigators in both academic and industry settings post-fellowship. Participants will benefit from ongoing feedback and mentorship, alongside a structured annual review process to assess project progress and personal development, accompanied by career counseling. Key Responsibilities Independent Research Leadership: Initiate and lead projects that explore innovative research avenues, utilizing dedicated resources for high-risk, high-reward investigations. Advancement of Core Mission: Play a crucial role in enhancing our knowledge of aging and age-related diseases. Scientific Innovation: Conduct experiments with precision, analyze data (including computational analysis if applicable), and troubleshoot methodologies as necessary. Publication of Results: Produce research suitable for timely submission to scientific journals upon completion of the fellowship. Collaboration and Communication: Engage actively with Calico's diverse teams and scientific community, presenting findings to audiences comprising computational scientists, lab scientists, and engineers. Professional Growth: Participate in a vibrant community of fellow postdoctoral researchers.

Join Xaira Therapeutics as a Senior Research Associate Scientist specializing in Display Technologies. In this pivotal role, you will be at the forefront of groundbreaking research and development initiatives that are shaping the future of therapeutic solutions. Your expertise will directly contribute to the innovation of our display technology, enhancing our product offerings and impacting the lives of patients worldwide.

Join AbbVie as an Associate Director in our R&D Information Research IT team, where you will play a pivotal role in driving innovation and supporting our research initiatives. In this hybrid position, you will collaborate with cross-functional teams to enhance our information systems and contribute to the advancement of groundbreaking therapies.

About UsCalico Life Sciences LLC, founded by Alphabet, is at the forefront of research and development dedicated to unraveling the complexities of human aging. Our mission is to leverage cutting-edge technologies and innovative model systems to deepen our understanding of the biology that governs aging. We aim to translate these insights into effective interventions, empowering individuals to live longer, healthier lives. Our dynamic laboratories, commitment to discovery-driven science, and robust drug-development pipeline foster an environment ripe for groundbreaking medical advancements.Calico Postdoctoral Fellowship ProgramWe invite passionate early-career scientists to embark on a transformative journey in aging research with us. This fellowship offers a distinctive opportunity to make a mark in the field of aging, enhance scientific expertise, and cultivate research independence.The Postdoctoral Fellowship is a fixed-term educational engagement lasting three years, with the possibility of a fourth-year extension and flexible start dates. Fellows will be fully integrated into Calico’s laboratories and scientific community.The program is tailored to prepare individuals for independent research roles in academia or industry upon completion. Fellows will receive ongoing mentorship, regular feedback, and participate in an annual review process to assess project progress and personal development while receiving career guidance.

About Us: Calico Life Sciences LLC, a pioneering research and development company founded by Alphabet, is dedicated to leveraging advanced technologies and modeling systems to deepen our understanding of the biology governing human aging. Our mission is to utilize this knowledge to create interventions that empower individuals to enjoy longer, healthier lives. With state-of-the-art technology labs, a firm commitment to curiosity-driven discovery science, and a dynamic drug-development pipeline in collaboration with academic and industry partners, Calico is an exhilarating environment for fostering medical breakthroughs. Role Overview: We are looking for a Senior / Staff Machine Learning Infrastructure Engineer to transform machine learning algorithms into practical applications and to construct a state-of-the-art computing and machine learning platform for analyzing biological datasets and modeling macromolecular sequences and structures. You will play a crucial role in a cross-functional initiative aimed at developing a premier computing and data analysis platform that underpins Calico's research endeavors through the following responsibilities: Develop and Optimize: Design and implement software infrastructure and tools that accelerate ML research, manage training and inference workflows, and streamline data ingestion and curation processes. Define Engineering Best Practices: Spearhead efforts to reorganize and refactor existing research codebases, enhancing code quality and reproducibility. Collaborate for Impact: Partner closely with our ML research scientists to deploy models that tackle critical questions in aging research and further Calico's mission. The ideal candidate will have extensive experience in designing, developing, and maintaining scalable and reliable ML infrastructure components, including data pipelines, model training and deployment systems, and monitoring tools. You should possess a proven track record of optimizing ML workflows for both performance and resource utilization, and remain updated on best practices in ML model management, versioning, and reproducibility. Effective communication and collaboration across functions are essential for executing complex projects successfully.