Director of Strategic Programs

Elevator PitchThe Director of Strategic Programs serves as a vital strategic ally to the CFO, overseeing comprehensive project management that includes M&A sourcing through integration, implementing change management for system upgrades, prioritizing budgets, and leading an enterprise PMO that facilitates transformative initiatives across the organization. In this role, you will be instrumental in managing the CFO’s operational framework, spearheading critical company-wide programs, and conducting business reviews focused on ROI that align with C-Suite objectives.Success in the Role (First 6–12 Months)In the first 30 days, you will:Establish strong connections with key stakeholders and partners, including the Executive Leadership Team, Finance, and other senior leaders.Align with CFO priorities, business rhythms, and the operational calendar (planning, forecasts, ELT/Board cycles, etc.).Implement functional reviews for strategic initiatives and budget planning.Within 90 days, you will:Initiate the organic investment review (ROIC model, tiered scorecards) to inform start/stop/continue decisions.Set up the Enterprise PMO cadence across IT projects, Contract Manufacturing change management, M&A funnel, and targeted value projects (e.g., software subscription expenditure reduction, indirect procurement, off-shoring).By the end of 12 months, you will:Deliver quantifiable ROI productivity (portfolio rebalanced; ROIC enhancement; cycle time reduction).Advance at least one M&A transaction through the stage gate process with a comprehensive Post Merger Integration plan.Achieve key transformation milestones with KPI improvements aligned with company objectives.Ensure service SLAs are met; maintain CFO time alignment above 85% on top priorities.The Work (What You’ll Do):Strategy & Internal Capital InvestmentLead the annual and long-range planning process alongside the CFO and CEO; translate strategic objectives into OKRs and decision memos.Manage internal operations and organic investment reviews utilizing ROIC/NPV scorecards; recommend rebalancing actions and ensure follow-through with the ELT.Collaborate with the ELT and junior staff across all functions to achieve related company goals.M&A / Corporate DevelopmentDevelop theses and maintain a target pipeline with the ELT; ensure consistent deal cadence and reporting.

At Xometry (NASDAQ: XMTR), we bridge the gap between visionary creators and the manufacturing powerhouses that turn their concepts into reality. Our dynamic digital marketplace equips manufacturers with essential resources to scale their businesses while enabling Fortune 1000 buyers to access unparalleled global manufacturing capabilities.As the Director of Partner Programs, you will play a pivotal role in orchestrating the synergy between Product, Operations, Finance, Marketing, Partner Success, and Leadership. Your mission will be to craft the strategy for expanding and refining Xometry's supplier network, overseeing key phases from acquisition and onboarding to engagement and retention.You will establish the vision, formulate the strategy, and manage initiatives designed to enhance our supplier base. Leading a focused team, you will collaborate closely with cross-functional partners to achieve tangible business results.

Deciphera Pharmaceuticals is excited to invite applications for the role of Associate Director of Program Leadership & Management. In this pivotal position, you will provide exceptional leadership and strategic direction to our Development and Commercial Program Teams. Collaborating closely with the Program Lead, you will be instrumental in advancing programs from early to late-phase clinical development and lifecycle management. The ideal candidate will exhibit a comprehensive understanding of drug development, thrive in ambiguous situations, and possess outstanding communication skills to foster effective collaboration within program teams and across the organization.This role demands a high level of cross-functional teamwork, engaging with both internal and external partners. You will be responsible for leading daily program management activities, including the formulation and implementation of the program's Integrated Development Strategy. A deep understanding of overall program strategy and critical path activities, as well as risk identification and mitigation planning, is essential.Key ResponsibilitiesStrategic Partnership with the Program Lead (50%)Collaborate with the Program Lead to develop and execute strategic, integrated development plans through effective leadership of Program Teams.Provide clear guidance on product development requirements to align with the expectations of external customers and business stakeholders.Monitor program progress and related KPIs, identifying gaps and risks while offering strategic recommendations.Support the execution and ongoing reassessment of development strategies in line with the overall corporate strategy.Operational Excellence Across Program Teams (50%)Facilitate program team meetings to ensure productive and efficient discussions.Ensure timely and clear communication of program strategies and progress to relevant stakeholders.Coordinate the integration of sub-teams to enhance the effectiveness of Program Teams.

Are you looking for an opportunity to work closely with a single sponsor while benefiting from the stability and growth opportunities provided by a global CRO? Join our team at ClinChoice, where we believe it's the best of both worlds. ClinChoice is actively seeking an Associate Director of Statistical Programming for a permanent position in a hybrid work model. This role offers a unique chance to lead crucial statistical strategies within a vibrant and fast-paced environment. This position is hybrid, preferably requiring candidates to travel to our client’s location in Waltham, MA. We are looking for a seasoned Associate Director of Programming to spearhead programming initiatives, develop scalable processes, and guarantee the delivery of high-quality outputs for regulatory submissions.

We are seeking a dedicated and dynamic Program Manager to join our team at Integrated Resources, Inc. in Waltham, Massachusetts. As a Program Manager, you will play a crucial role in leading and coordinating various projects, ensuring they are executed efficiently and effectively. Your expertise will help drive our initiatives forward, fostering collaboration across teams and stakeholders.

Join Xometry, a leading platform in manufacturing technology, as a Senior Manager for Strategic Deals within the Aerospace & Defense sector. In this pivotal role, you will spearhead initiatives that drive strategic partnerships and enhance our market position. Your expertise in negotiating high-stakes contracts and your deep understanding of the aerospace and defense industry will be key to your success. Collaborate with cross-functional teams to identify opportunities, develop proposals, and manage relationships with key stakeholders.

At ZoomInfo, we are where careers take off. Our fast-paced environment fosters bold thinking and empowers you to produce your best work. You'll collaborate with passionate teammates who support one another, challenge the status quo, and celebrate collective achievements. With innovative tools that enhance your contributions and a culture that nurtures your ambition, you'll not only participate—you'll drive impactful outcomes swiftly.We pride ourselves on our commitment to creativity, innovation, teamwork, accountability, and results. If you are a proactive individual who takes initiative and delivers results, we want to hear from you! Our aspirations are high, and we are in search of exceptional individuals to help us realize our vision. We continually strive to enhance every aspect of our organization, employing cutting-edge technologies and methodologies to delight our customers and accelerate revenue growth.The Senior Strategic Partner Manager, Solutions is a pivotal role within our Partner organization. This position is responsible for establishing a global program that empowers ZoomInfo’s premier implementation partners to achieve successful project outcomes and ensure sustained customer adoption. You will work closely with ZoomInfo’s Solutions Team and report directly to the Sr AVP of Partnerships, ensuring the program's success aligns with ZoomInfo’s overarching solutions partner strategy.Key Responsibilities:Design and manage a comprehensive Global Solutions Partner Program that equips partners to achieve successful project outcomes and enhance ongoing customer adoption while elevating partners’ technical competencies and maturing their ZoomInfo services practice.Collaborate with the partner team, delivery, and account teams to implement essential program elements, resources, and processes that support partner success.Oversee program strategy, project management, and provide timely updates on key initiatives for partner success.Serve as a trusted advisor for ZoomInfo solutions partners while contributing as a player/coach as the team expands.Work in partnership with internal and external stakeholders to develop repeatable frameworks derived from successful customer deployments.Gather qualitative and quantitative metrics to assess and report on partner performance based on key performance indicators (KPIs) to ensure high-quality implementations from our top partners.Actively contribute to the evolution of ZoomInfo’s partner program and strategic direction.Architect and manage various partner initiatives...

Xometry is seeking a dynamic and experienced Human Resources Program Manager to join our team in Waltham, MA. In this role, you will be responsible for driving HR initiatives that support our business objectives, enhance employee engagement, and foster a high-performance culture.Your expertise in managing HR programs will be essential in developing strategies to attract, retain, and develop top talent. You will collaborate with various departments to implement best practices in talent management, performance evaluation, and employee development.

About Oruka Therapeutics Oruka Therapeutics (Nasdaq: ORKA) develops biologic therapies for chronic skin diseases, with a focus on achieving complete disease clearance for patients with conditions like plaque psoriasis. The company’s antibody portfolio, created in partnership with Paragon Therapeutics, targets the underlying mechanisms of dermatologic and inflammatory diseases. Oruka’s goal is to offer patients long-lasting relief, potentially with just one or two treatments per year. Learn more at www.orukatx.com. Position Details Title: Director/Senior Medical Director, Clinical Development (Multiple openings) Location: Remote or hybrid. For those near Waltham, MA or Menlo Park, CA, hybrid work is available (3 days per week in office). Role Overview The Director or Senior Medical Director, Clinical Development, leads and supports clinical trials across Oruka’s pipeline. This role shapes clinical study design, oversees trial execution, and interprets data to validate product safety and efficacy. Collaboration with internal teams and external partners is central, ensuring clinical activities align with regulatory, scientific, and business goals. Main Responsibilities Clinical Trial Design and Oversight: Help develop clinical trial protocols, including patient selection, study endpoints, and data collection plans. Oversee the conduct of clinical trials at study sites, ensuring adherence to protocols and Good Clinical Practice (GCP) standards. Review and interpret trial data to evaluate the safety and efficacy of investigational products.

At Crescent Biopharma, we aspire to transform the landscape of oncology by developing cutting-edge therapies tailored for cancer patients. Our innovative pipeline includes a leading PD-1 x VEGF bispecific antibody, alongside state-of-the-art antibody-drug conjugates. By harnessing diverse therapeutic modalities and established targets, we aim to expedite the development of potentially groundbreaking treatments, whether as standalone interventions or in combination therapies targeting various solid tumors. For more insights into our mission and vision, visit our website and connect with us on LinkedIn and X.We are currently in search of an Associate Director or Director of Analytical & GMP Quality Assurance Operations. In this pivotal role, you will oversee and guide the QA functions related to analytical development, quality control operations, and GMP quality activities across our clinical-stage biologics and ADC programs. Collaboration with cross-functional teams, including CMC, Analytical Sciences, Quality Control, and Technical Operations, as well as external manufacturing and testing partners, will be key to ensuring compliance with phase-appropriate GMP standards, maintaining data integrity, and ensuring inspection readiness within a dynamic outsourced operational framework. Your strategic vision will be instrumental in shaping Crescent's analytical quality strategy and driving the disciplined execution of core quality systems that align with our aggressive development timelines.

Join Our Mission:Oruka Therapeutics (Nasdaq: ORKA) is at the forefront of developing cutting-edge biologics aimed at revolutionizing the treatment of chronic skin diseases. Our commitment is to provide patients afflicted by conditions such as plaque psoriasis with unprecedented freedom by achieving significant disease clearance with infrequent dosing—sometimes as little as once or twice a year. We are advancing a proprietary pipeline of potentially best-in-class antibodies that target the fundamental mechanisms of plaque psoriasis and other dermatological and inflammatory ailments. Discover more about us at www.orukatx.com.As we expand our core team, we are looking for exceptional individuals who are not just seeking employment but are passionate about contributing to a broader cause. We value candidates who are eager to foster an inclusive and dynamic company culture.Position Overview:We are in search of a seasoned and motivated leader in regulatory CMC to shape our strategy and execution across various stages of biologics programs. In this role, you will be responsible for the development of high-quality regulatory CMC submissions and will provide guidance to cross-functional teams on global regulatory expectations appropriate for different phases. Ideal candidates will bring extensive expertise in biologics development and manufacturing, particularly in drug substance and product CMC submissions. You will play a crucial role in influencing program strategies, facilitating collaboration across CMC, QA, RA, Supply Chain, and external partners, and driving pivotal decisions that support our expanding biologics pipeline. This highly visible role involves ensuring compliance with FDA, EMA, ICH, and WHO guidelines while meeting corporate and program-level objectives.

Xometry (NASDAQ: XMTR) is at the forefront of empowering the industries of today and tomorrow by connecting visionary thinkers with manufacturers capable of turning their ideas into reality. Our digital marketplace equips manufacturers with essential resources for business growth while facilitating effortless access to global manufacturing capabilities for buyers at Fortune 1000 companies.We are on the lookout for a highly motivated and experienced Program Manager, Operations to become a vital part of our dynamic and innovative team. This role is pivotal in managing cross-functional initiatives aimed at improving operational efficiency, enhancing scalability, and propelling our growth in advanced manufacturing. Candidates with a background in the automotive or manufacturing industry will be given priority.

Role overview The Senior Engineering Program Manager at Boston Engineering Corporation oversees projects from early concept stages to final delivery. Based in Waltham, this position manages the full project lifecycle, ensuring that engineering teams stay aligned with client needs and expectations. Success in this role depends on strong coordination with cross-functional groups. The Senior Engineering Program Manager works closely with colleagues across disciplines to keep projects on track and deliver solutions that meet specific client requirements. Key responsibilities Lead engineering projects from concept through completion Coordinate with teams across functions to ensure effective project execution Focus on delivering solutions that address each client’s requirements Location This role is based in Waltham.

Crescent Biopharma is on a mission to revolutionize oncology by developing innovative therapies for cancer patients. Our clinical-stage pipeline features a cutting-edge PD-1 x VEGF bispecific antibody, along with a range of novel antibody-drug conjugates. By harnessing various modalities and established targets, we strive to expedite the development of potentially transformative treatments, whether as standalone therapies or in combination regimens targeting multiple solid tumors. Discover more about our groundbreaking work at www.crescentbiopharma.com and follow us on LinkedIn and Twitter.As the Program Team Leader (PTL), you will be a dedicated drug developer with a global outlook and a strong business orientation. We seek an adaptable leader who possesses strategic product development expertise and an unwavering commitment to advancing our mission. Your role will encompass overseeing project execution, fostering team collaboration, and driving initiatives that align with our vision for transforming cancer care.

Role Overview Crescent Biopharma seeks a Director or Senior Director of Clinical Business Operations in Waltham, MA. This leader guides clinical operations strategy and oversees a team dedicated to the execution of clinical trials. The role involves close collaboration with multiple departments to keep projects on track and compliant with regulatory standards. Key Responsibilities Shape and refine clinical operations strategy Lead and mentor the clinical business operations team Work cross-functionally to support clinical trial execution Optimize processes and manage operational resources Maintain compliance with all relevant regulatory requirements

Join AbbVie’s Medical Affairs team and make a difference in the lives of patients battling ovarian solid tumors. Our organization is dedicated to providing healthcare professionals and patients with the vital information and solutions necessary to utilize AbbVie products safely and effectively throughout their healthcare journey.As the Scientific / Medical Director, you will play a pivotal role in shaping the strategic and operational aspects of our Oncology portfolio. Your expertise will contribute to healthcare interactions, the generation of clinical data, educational initiatives, and the safeguarding of patient safety through risk minimization and safety surveillance activities.This position requires close collaboration with our commercial and R&D teams, ensuring that medical insights drive our core medical, brand, and access strategies as we navigate the evolving therapeutic landscape.

We are in search of a highly skilled Director of Biostatistics to take on the role of Study Statistician across several drug development programs. This pivotal position will involve crafting statistical strategies from the early stages of development through to regulatory submissions, collaborating cross-functionally to facilitate data-driven decision-making while upholding scientific and regulatory standards.Key ResponsibilitiesDevelop and oversee statistical strategies for various clinical studies throughout all phases of development.Contribute to Clinical Development Plans and represent Biostatistics in cross-functional teams.Design clinical studies, author and review protocols and Statistical Analysis Plans (SAPs), and supervise interim and final analyses.Ensure the quality, accuracy, and reproducibility of statistical outputs in partnership with programming teams and CROs.Assist with regulatory submissions (including INDs, NDAs, BLAs, MAAs), including interactions with health authorities and integrated summaries (ISS/ISE).Oversee external vendors and mentor junior statisticians or contractors.Contribute to scholarly publications, conference presentations, and continuous improvement initiatives.

Role Overview Sobi is hiring a Director of HOVA to guide the strategic and operational direction of HOVA projects in Waltham. This leader will shape priorities, manage execution, and ensure projects support Sobi’s mission to improve healthcare outcomes. Key Responsibilities Oversee HOVA project strategy and daily operations Align initiatives with company goals and mission Promote collaboration across teams and departments Support growth and strengthen Sobi’s position in the market

Are you excited about the prospect of working closely with a dedicated sponsor while enjoying the stability and diverse career avenues that a global CRO provides? Our team believes it’s the ideal combination... ClinChoice is on the lookout for a Manager of Statistical Programming to join our client’s team in a permanent capacity—an extraordinary opportunity to spearhead significant statistical strategies in an engaging environment. This is a Hybrid position, with a preference for candidates who can commute to our client’s location in Waltham, MA. Role Overview We are in search of a seasoned and driven Manager of Statistical Programming to oversee programming initiatives within the Biometrics department. This role will be responsible for managing clinical programming deliverables, ensuring quality and compliance, facilitating regulatory submissions, and mentoring a team of programmers. The ideal candidate will possess strong proficiency in SAS (and/or R), comprehensive knowledge of CDISC standards, experience with oncology clinical trials, and exceptional leadership capabilities. Key Responsibilities:

Join Deciphera Pharmaceuticals as the Director of Legal Compliance, where you will play a pivotal role in ensuring the integrity and compliance of our legal operations. You will lead initiatives that uphold our commitment to ethical standards while navigating the complex regulatory landscape of the pharmaceutical industry.Your responsibilities will include developing and implementing compliance programs, conducting audits, and providing guidance on legal matters. You will work closely with various departments to promote a culture of compliance and minimize legal risks.