Principal Research Scientist II

Join AbbVie as a Principal Research Scientist II, where you will leverage your expertise to drive innovative research projects. Collaborate with a dynamic team of scientists and contribute to groundbreaking advancements in healthcare. This role offers the opportunity to work on complex problems, develop novel solutions, and make a significant impact in the field of research.

AbbVie Inc. is hiring a Principal Research Scientist I in Worcester to contribute to research and development in drug discovery. The role centers on experimental design, hands-on laboratory work, and close collaboration across departments. Key Responsibilities Design and execute laboratory experiments to meet research objectives Analyze data and interpret experimental results Work with colleagues from different teams to solve scientific problems Use scientific knowledge to move drug discovery projects forward Role Impact This position plays a direct part in developing new therapies with the goal of improving patient outcomes.

Role Overview AbbVie Inc. is hiring a Scientist II for the Immunopharmacology group in Worcester. This position centers on peptide discovery and research. The scientist will contribute expertise to advance research projects and support the development of new therapeutic solutions.

Join our dynamic and innovative team at AbbVie, where we are dedicated to developing groundbreaking mRNA platforms. As a Scientist II, you will contribute to cutting-edge research and development efforts aimed at advancing therapeutic solutions in a collaborative environment.

About the Role AbbVie is hiring a Scientist II for the Multispecifics Engineering group within Discovery Biotherapeutics in Worcester. This position centers on designing and developing new biotherapeutic solutions that target important healthcare challenges. What You Will Do Apply scientific knowledge to create and advance biotherapeutic candidates Work closely with colleagues from different disciplines to move projects from early concepts through execution Support AbbVie's mission to improve patient outcomes through innovative research

Role Overview AbbVie Inc. is hiring a Principal Machine Learning Scientist II to support research and development in Biotherapeutics and Genetic Medicine. This position is based in Worcester. What You Will Do Apply advanced machine learning methods to accelerate research projects in genetic medicine. Contribute expertise to develop new approaches and support scientific initiatives within the biotherapeutics space.

Role Overview AbbVie is seeking a Scientist II for Purification Development in Worcester. This position focuses on improving purification processes that support the creation of new therapeutics. The Scientist II works closely with other scientists to drive process improvements and support research goals. What You Will Do Develop and refine purification methods for therapeutic products Collaborate with colleagues to troubleshoot and optimize laboratory protocols Apply advanced technologies to increase process efficiency and reliability Contribute scientific expertise to team discussions and project planning About AbbVie AbbVie is a global biopharmaceutical company dedicated to discovering and delivering innovative medicines that address serious health issues.

Role Overview AbbVie Inc. is hiring a Senior Scientist II with a focus on Occupational and Environmental Toxicology for its Worcester location. This position centers on advanced research and risk assessments to support product safety and regulatory compliance. What You Will Do Conduct scientific research in occupational and environmental toxicology. Perform risk assessments related to product safety and workplace exposures. Support compliance with health, safety, and environmental regulations. Advise teams on toxicological risks and mitigation strategies. Contribute expertise to initiatives promoting health and environmental sustainability. Impact This role shapes AbbVie's approach to health and environmental safety through direct scientific input and collaboration across teams.

About the Role AbbVie is seeking a Senior Scientist II with a focus on Immunopharmacology and Peptide Discovery to join the team in Worcester. This position centers on leading research efforts that support the discovery and development of new peptide-based therapeutics. The work directly contributes to advancing AbbVie's drug development pipeline. What You Will Do Lead research projects in immunopharmacology and peptide discovery. Design and execute experiments to identify and characterize novel peptide therapeutics. Apply expertise in immunology and pharmacology to support drug development goals. Collaborate with multidisciplinary teams to move promising candidates forward. Location This position is based in Worcester.

AbbVie Inc. seeks an Associate Scientist in Process Development I to join its Worcester team. This entry-level position plays a key role in supporting the development and optimization of therapeutic product processes. The work centers on advancing products through hands-on laboratory efforts and teamwork. Key responsibilities Assist in developing and refining processes for therapeutic products Collaborate with scientists from diverse backgrounds to meet project objectives Build practical laboratory experience in process development Work environment The role is based on-site in Worcester, where close collaboration and daily interaction with the process development team are expected.

AbbVie Inc. seeks a Scientist I specializing in Complex In Vitro Models at its Worcester, MA location. This role contributes to research aimed at advancing drug development and supporting the creation of new therapies. Key responsibilities Design and conduct experiments to explore complex biological pathways using advanced in vitro systems. Collaborate with teams across different functions to plan and carry out research projects. Share research findings that help guide drug development and contribute to bringing new treatments to patients. Location This position is based in Worcester, Massachusetts.

AbbVie is seeking a highly motivated Senior Scientist I specializing in Multi-specific Biologics to join our innovative research team in Worcester, Massachusetts. In this role, you will contribute to the design, development, and optimization of multi-specific biologic therapeutics that target complex diseases. Your expertise will drive the advancement of cutting-edge therapeutic modalities, enhancing our pipeline of biologic products.

Join AbbVie, a global leader in biopharmaceutical innovations, as a Senior Scientist I specializing in Bioinformatics, Biotherapeutics, and Genetic Medicine. In this pivotal role, you will contribute to groundbreaking research and development efforts aimed at transforming patient care through advanced genetic therapies.Your expertise will guide the analysis of complex biological data, drive strategic decision-making, and enhance our understanding of biotherapeutic mechanisms. Collaborate with cross-functional teams to innovate and implement solutions that make a meaningful impact in the field of medicine.

Job Overview:We are looking for a dynamic and collaborative technical leader to spearhead the innovation and development of our lipid nanoparticle (LNP) platform technology. The ideal candidate will engage with cross-functional teams to design and enhance LNPs and tLNP platform technology, supporting our innovative pipeline. This role involves establishing and directing our LNP innovation strategy, focusing on lipid design, chemistry, formulations, and targeted non-viral delivery systems, with a vision towards future product development and pipeline expansion. Key Responsibilities:Act as a scientific and technical authority within the organization, particularly in LNP-based drug delivery systems for nucleic acids.Drive the innovation, development, and optimization of the targeted LNP platform to support programs across various therapeutic areas.Possess an in-depth understanding of lipid and LNP design principles, stability, and scale-up processes, ensuring successful transition of drug product formulation production and purification unit operations from bench to larger scales.Develop LNP-related project plans, timelines, and budget forecasts, ensuring alignment with key stakeholders and organizational objectives.Lead the analysis of complex data sets, clearly communicating findings during internal program meetings, cross-functional reviews, and governance forums.Collaborate extensively with discovery and development teams, including mRNA, antibody, analytical, and process development groups, to propel pipeline initiatives.Oversee the drafting, review, and approval of technical reports pertinent to the function.Manage and mentor a team of over 10 scientists and associates across AbbVie’s East and West Coast sites. 

Role Overview AbbVie Inc. is hiring a Principal Data Architect II for the Biotherapeutics and Genetic Medicine group in Worcester. This role focuses on strengthening data management and supporting research through effective data architecture and design. What You Will Do Work with teams from different functions to define and document data requirements for biotherapeutics and genetic medicine projects. Design and build data architecture solutions that support research, development, and operations. Apply best practices in data governance to maintain data integrity and make critical data accessible across platforms. Contribute to the overall data strategy and help shape the direction of advanced analytics tools for R&D. About the Team This team specializes in biotherapeutics and genetic medicine, with a focus on supporting innovative research through strong data foundations.

As a Lead Principal Instrumentation & Controls Engineer at AbbVie, you will spearhead the design, implementation, and qualification of the automation and controls input/output layer for GMP facilities and laboratories. This critical role merges expertise in process, IT/OT, and quality systems to ensure compliant and reliable operations. You will be responsible for developing comprehensive I&C design packages, configuring DCS/PLC systems (primarily FoxBoro and DeltaV), and overseeing FAT/SFAT/SAT processes in accordance with CSV requirements. Your technical leadership will support project execution while advancing AbbVie’s Clinical and Commercial Drug Substance manufacturing processes.Key Responsibilities:Champion a safe working environment in line with all environmental health, safety, and maintenance standards.Provide technical guidance for daily operational support in Upstream and Downstream Drug Substance manufacturing.Manage change control, nonconformance, corrective and preventative actions, as well as commissioning and qualification activities.Demonstrate proficiency in various instrumentation, specifically with Rockwell PLC and Emerson DeltaV platforms.Offer on-site operational support 24/7 on a rotational basis.Troubleshoot manufacturing instrumentation and control system issues while optimizing control strategies for improved safety and efficiency.Lead front-end engineering design (FEED) and detailed design for I&C scope, including defining I/O allocations, network topologies, and panel architectures.Produce detailed I&C design packages encompassing enclosure details, panel layouts, terminal block specifications, and network integration.Oversee the fabrication of control panels and field integration while managing vendor electrical and instrumentation scopes.Plan and carry out site acceptance testing (SAT) and assist with operational qualification (OQ) and commissioning processes.Execute tasks in a Good Practice (GxP) compliant manner, ensuring full traceability and change control in accordance with CSV practices and 21 CFR Part 11 standards.Drive continuous improvement initiatives in collaboration with Plant Engineering, Maintenance, and Manufacturing teams to enhance operational efficiency.Engage with the AbbVie global network to share and implement continuous improvement opportunities within Drug Product manufacturing.

Role OverviewJoin AbbVie as a Manufacturing Technician II, where you will play a crucial role in our cGMP manufacturing operations within our biologics production facility. Collaborate with engineers for set-up and calibration tasks while executing rework and quality testing processes for various parts, components, and final materials. Utilize advanced software systems (including LIMS, SAP, and automated control systems) to gather and analyze operational data, enabling real-time adjustments to products and equipment. You will also contribute to the development and refinement of methods and procedures aimed at optimizing the manufacturing process.Key ResponsibilitiesOversee the shipping of finished materialsManage and maintain inventory levelsConduct sampling of in-process and raw materialsOperate glass washers and autoclavesPrepare buffers and mediaPrepare equipment for cleaning in place (CIP) and sterilization in place (SIP)Engage in cell culture processes from vial thaw to production scaleExecute column chromatography and tangential flow filtration

Are you a driven professional eager to advance your career with a dynamic and growing consulting and engineering firm? Do you seek an organization that prioritizes your professional development and skill enhancement? If you're ready to take your career to the next level, consider joining Apex!With impressive sales growth, high client retention rates, strategic acquisitions, and a culture of entrepreneurship, Apex Companies stands as one of the fastest-growing engineering and environmental consulting firms in the United States. Recently recognized by the Zweig Group for our rapid growth in the AEC industry, we take pride in delivering exceptional service and have earned numerous accolades for project excellence. As we continue to expand, we invite you to grow with us.Apex is enhancing our Infrastructure Practice and is on the lookout for a Principal-level leader to spearhead our Water/Wastewater business in key Northeast markets, including Worcester or Springfield, Massachusetts; Manchester, New Hampshire; and Southwest Connecticut.This position will initially operate remotely with plans to establish a local office in one of the target markets. Upon opening the office, the role will transition to a hybrid work model.This strategic growth opportunity is ideal for a seasoned, client-facing professional with a robust municipal network and an active client portfolio. The successful candidate will oversee business development and project execution for municipal water, wastewater, and stormwater infrastructure projects, leveraging Apex’s national resources and multidisciplinary teams.If you are an entrepreneurial leader with a proven history of market development, securing projects, and delivering impactful infrastructure initiatives, we encourage you to join Apex and contribute to shaping the future of our Infrastructure growth.We offer a sign-on bonus and relocation assistance for the right candidate.