About the job
Attention recruitment agencies: All agency inquiries are managed exclusively through 4DMT’s internal Talent Acquisition team. Unsolicited resumes will not be accepted. Agencies must engage with the Talent Acquisition team for any requisition. Direct contact with hiring managers is prohibited and may affect future collaborations with 4DMT.
4D Molecular Therapeutics (4DMT) is a pioneering late-stage biotechnology enterprise focused on the development of durable and disease-targeted therapeutics that have the potential to revolutionize treatment approaches and provide unparalleled advantages to patients. Our flagship product candidate, 4D-150, is designed as a foundational therapy for addressing blinding retinal vascular diseases, offering years of sustained delivery of anti-VEGF (aflibercept and anti-VEGF-C) through a single, safe intravitreal injection, significantly alleviating the treatment burden linked to traditional bolus injections. Currently, 4D-150 is in Phase 3 development for wet age-related macular degeneration, with diabetic macular edema as its second indication. Additionally, our second product candidate, 4D-710, represents the first known genetic medicine that successfully delivers and expresses the CFTR transgene in the lungs of individuals with cystic fibrosis via aerosol delivery.
GENERAL SUMMARY:
The Clinical Technology Manager, IT, is responsible for the strategic oversight, delivery, and operational integrity of information systems that support 4DMT’s Clinical Research and Development organization. This role guarantees that clinical systems are not only fit for purpose but also inspection-ready, while continuously advancing technology solutions to facilitate efficient and compliant clinical execution.
The individual in this role acts as the primary liaison among Clinical R&D, Data Management, IT, and external vendors, ensuring alignment, governance, and disciplined ownership of systems throughout their lifecycle—from design and implementation to operation and retirement.
MAJOR DUTIES & RESPONSIBILITIES:
- Serve as the accountable owner for clinical systems, managing access control, configuration, validation, and lifecycle management.
- Ensure compliance with GxP regulations and internal SOPs, maintaining data integrity and readiness for inspection.
- Lead the definition of requirements, solution design, and implementation planning in collaboration with cross-functional stakeholders.
- Provide Level-2 application support and coordinate with vendors for incident resolution and system enhancements.
- Continuously improve system documentation and processes.

