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Experience Level
Senior
Qualifications
Key Responsibilities:Prepare samples from diverse sources, including proteins, cells, tissues, and biofluids.Optimize, develop, and implement chemoproteomics and proteomics sample preparation techniques.Maintain and troubleshoot various instruments, including HPLCs and mass spectrometers.Analyze and interpret data for collaboration purposes.Present findings at internal lab and company-wide meetings.Required Qualifications:PhD in Analytical Chemistry, Chemistry, Chemical Biology, Biochemistry, Chemical Engineering, or a related discipline.At least 5 years of relevant post-PhD experience in the biopharmaceutical sector.Proven expertise in method development for HPLC and/or mass spectrometers.Hands-on experience in maintaining and troubleshooting HPLC and mass spectrometry equipment.Familiarity with sample preparation for proteomics and chemoproteomics.Experience in multiplexed proteomics techniques, such as TMT.Knowledge of enrichment and analysis of post-translational modifications (PTMs).Expertise in activity-based proteome profiling and cysteine enrichment workflows (e.g., CysPAT, DBIA).Proficient in proteomics data analysis and programming skills are a plus.
About the job
About Us:
Calico Life Sciences LLC, founded by Alphabet, is a pioneering research and development entity dedicated to advancing our understanding of human aging through cutting-edge technologies and model systems. Our mission is to leverage this knowledge to develop interventions that promote longer, healthier lives. At Calico, we foster a culture of curiosity-driven science, supported by a robust drug-development pipeline in collaboration with leading academic and industry partners, making us a dynamic environment for medical innovation.
Position Overview:
We are on the lookout for a seasoned Scientist to join our mass spectrometry proteomics team. The ideal candidate will exhibit enthusiasm, attention to detail, and exceptional organizational skills while tackling complex scientific challenges. This role focuses on employing chemoproteomics techniques via mass spectrometry to facilitate drug discovery, involving extensive sample handling and optimization of proteomics methodologies to propel our drug discovery initiatives forward.
About Calico Life Sciences LLC
Calico Life Sciences LLC is a groundbreaking research and development organization established by Alphabet, committed to exploring the biology of human aging. Our innovative approach integrates advanced technologies to create groundbreaking solutions that enhance health span and longevity. With a rich pipeline of drug development initiatives, we collaborate with leading scientists and institutions to make significant impacts in the field of healthcare.
Clicking Apply Now takes you to AutoApply where you can tailor your resume and apply.
Unlock Your Potential
Generate Job-Optimized Resume
One Click And Our AI Optimizes Your Resume to Match The Job Description.
Is Your Resume Optimized For This Role?
Find Out If You're Highlighting The Right Skills And Fix What's Missing
Experience Level
Senior
Qualifications
Key Responsibilities:Prepare samples from diverse sources, including proteins, cells, tissues, and biofluids.Optimize, develop, and implement chemoproteomics and proteomics sample preparation techniques.Maintain and troubleshoot various instruments, including HPLCs and mass spectrometers.Analyze and interpret data for collaboration purposes.Present findings at internal lab and company-wide meetings.Required Qualifications:PhD in Analytical Chemistry, Chemistry, Chemical Biology, Biochemistry, Chemical Engineering, or a related discipline.At least 5 years of relevant post-PhD experience in the biopharmaceutical sector.Proven expertise in method development for HPLC and/or mass spectrometers.Hands-on experience in maintaining and troubleshooting HPLC and mass spectrometry equipment.Familiarity with sample preparation for proteomics and chemoproteomics.Experience in multiplexed proteomics techniques, such as TMT.Knowledge of enrichment and analysis of post-translational modifications (PTMs).Expertise in activity-based proteome profiling and cysteine enrichment workflows (e.g., CysPAT, DBIA).Proficient in proteomics data analysis and programming skills are a plus.
About the job
About Us:
Calico Life Sciences LLC, founded by Alphabet, is a pioneering research and development entity dedicated to advancing our understanding of human aging through cutting-edge technologies and model systems. Our mission is to leverage this knowledge to develop interventions that promote longer, healthier lives. At Calico, we foster a culture of curiosity-driven science, supported by a robust drug-development pipeline in collaboration with leading academic and industry partners, making us a dynamic environment for medical innovation.
Position Overview:
We are on the lookout for a seasoned Scientist to join our mass spectrometry proteomics team. The ideal candidate will exhibit enthusiasm, attention to detail, and exceptional organizational skills while tackling complex scientific challenges. This role focuses on employing chemoproteomics techniques via mass spectrometry to facilitate drug discovery, involving extensive sample handling and optimization of proteomics methodologies to propel our drug discovery initiatives forward.
About Calico Life Sciences LLC
Calico Life Sciences LLC is a groundbreaking research and development organization established by Alphabet, committed to exploring the biology of human aging. Our innovative approach integrates advanced technologies to create groundbreaking solutions that enhance health span and longevity. With a rich pipeline of drug development initiatives, we collaborate with leading scientists and institutions to make significant impacts in the field of healthcare.