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Lead Bioinformatics Engineer - Scientific Pipelines

MithrlSan Francisco
On-site Full-time

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Experience Level

Manager

Qualifications

Experience in designing and maintaining production-grade bioinformatics pipelines across diverse data modalities including microarray, cell painting, WGS, WES, spatial transcriptomics, flow cytometry, ATAC-seq, and methyl-seq. Proficiency in building workflows using Nextflow, nf-core modules, or similar frameworks, emphasizing reproducibility, validation, and scalability. Strong background in implementing quality control, validation, and provenance tracking for all supported modalities. Collaborative experience with data teams to ensure pipeline outputs align seamlessly with Mithrl’s internal schemas, including variable ID coercions and metadata normalization.

About the job

Join Mithrl as a Lead Bioinformatics Engineer

At Mithrl, we envision a future where groundbreaking medicines are swiftly delivered to patients, transforming the landscape of health care.

Mithrl is pioneering the world's first commercially available AI Co-Scientist, a revolutionary discovery engine that converts complex biological data into actionable insights in mere minutes. By simply asking questions in natural language, scientists receive immediate responses with comprehensive analyses, innovative targets, hypotheses, and patent-ready reports.

Our impressive growth trajectory includes:

  • 12X year-over-year revenue growth

  • Trusted by top-tier biotech firms and major pharmaceutical companies across three continents

  • Facilitating real breakthroughs from target discovery to patient outcomes.

About the Role

We are in search of an innovative Lead Bioinformatics Pipeline Engineer to architect and expand Mithrl’s multimodal scientific processing pipelines. You will be responsible for developing workflows that convert raw biological data into clean, reproducible outputs that fuel Mithrl’s AI Co-Scientist. Your work will encompass a range of modalities including microarray, imaging, spatial transcriptomics, genomics, epigenomics, flow cytometry, and more.

This pivotal role lies at the core of our technical infrastructure. You will design Nextflow and nf-core style pipelines, implement modality-specific validation and quality control layers, and collaborate closely with our Tabular Data Team and Knowledge Curation Team to ensure seamless data harmonization, variable ID mapping, and schema alignment. Your contributions will enable scientists to pose inquiries and receive accurate, data-driven answers instantaneously.

If you are passionate about constructing robust scientific workflows and tackling high-impact challenges, you will find your place here.

About Mithrl

Mithrl is at the forefront of biopharmaceutical innovation, committed to accelerating the pace of drug discovery and development. Our AI-driven technology is transforming how scientists analyze and interpret biological data, making significant strides towards faster and more effective treatments for patients worldwide.

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