Senior Infrastructure Engineer

About Our TeamThe Infrastructure Engineering team operates within the IT department, dedicated to the reliable construction, deployment, and management of critical on-premises and hybrid environments that empower our internal services and vital research and development projects.This newly established team is committed to implementing rigorous Site Reliabilit…

Plasmidsaurus helps scientists worldwide by streamlining sequencing. Researchers from leading institutions and companies rely on this platform daily. With a global network of labs, the company delivers fast, affordable sequencing results, and has recently expanded into RNA-seq to broaden its genomics reach. The team is focused on building a universal sequencing platform designed for efficiency and global scale. Role overview The Lead Engineer for AI Infrastructure in Platform Engineering sets both technical direction and management strategy for the company’s compute, data, AI, and security infrastructure. This position oversees the entire sequencing operation, from laboratory devices to data delivery. What you will do Oversee core services that coordinate laboratory devices, including robots, sequencers, and on-premises Linux servers, as well as the data ingestion pipeline. Develop cloud infrastructure and data pipelines for storing, processing, and delivering terabytes of sequencing data. Design systems to manage millions of bioinformatics tasks, handling queue management, workflow orchestration, and scheduling. Build AI infrastructure and internal tools to support autonomous systems, including: Quality Scientist Agents: Monitor operations, detect anomalies, and escalate quality or reliability concerns. Logistics Agents: Coordinate global transportation of samples to labs and carriers. Bioinformatics Coding Agents: Run adaptive analyses on varied sample types with different data distributions. Culture The team values initiative and a strong sense of ownership. High agency and responsibility shape how work gets done at Plasmidsaurus.

Sphere develops AI-driven systems that help businesses navigate and comply with global trade laws. The core platform, TRAM, interprets regulations across more than 190 jurisdictions, enabling clients to stay compliant with speed and accuracy. Backed by a16z and Y Combinator, Sphere operates from its San Francisco headquarters. Role overview The AI Agent Infrastructure Lead guides the technical direction of Sphere’s AI agent infrastructure. This position sits within a small, collaborative team where each person’s contributions directly influence company growth. Sphere’s mission centers on automating compliance for global transactions, from calculation to remittance, to improve efficiency and market access. High reliability is essential, systems are engineered for zero downtime. What you will do Lead technical strategy and architecture for AI agent infrastructure Collaborate closely with a tight-knit team at the San Francisco HQ Ensure systems remain highly reliable and available Why Sphere? Tackle complex infrastructure challenges that affect real-world trade Make a direct impact on a product trusted in over 190 jurisdictions Work alongside a small, dedicated team shaping the company’s future Contribute to the evolution of compliance technology in a rapidly growing company

Role overview Baseten seeks an Infrastructure Finance Lead in San Francisco. This position focuses on designing and carrying out financial strategies that support the company’s infrastructure. The role requires frequent collaboration with teams across the business to strengthen financial results and guide planning. What you will do Develop and execute financial strategies for infrastructure projects Partner with teams from different functions to assess and improve financial performance Use analytical skills to inform strategic planning and allocate resources effectively Location This role is based in San Francisco.

Role Overview Nextdata is hiring a Lead Principal Infrastructure Engineer in San Francisco, CA. This position focuses on building the foundation for a decentralized data mesh platform, supporting data ownership and enabling AI, machine learning, and analytics at scale. What You Will Do Develop automation solutions for provisioning and managing the Nextdata OS across multiple cloud platforms. Work closely with the founding engineering team to design and implement a secure, self-service infrastructure for future data product developers. Own the architecture and deployment of the OS, using infrastructure-as-code to ensure high code quality and scalability. Engage directly with customers to understand their requirements and translate feedback into technical improvements. Collaborate with product teams to align infrastructure capabilities with business needs. What You Bring Expertise in large-scale distributed systems and data infrastructure. Experience designing, deploying, and maintaining cloud-based platforms. Strong background in infrastructure-as-code and automation. Ability to work collaboratively with engineering and product teams. Comfort engaging with customers to gather feedback and requirements.

About LightfieldLightfield is an innovative AI-driven CRM that seamlessly integrates information from your email, calendar, and meetings. It captures every interaction, transforming it into organized context—managing accounts, tasks, follow-ups, and insights—so that nothing is overlooked.We are redefining CRM from the ground up. Rather than forcing teams into rigid frameworks, Lightfield adapts to the real working styles of companies, automating processes and revealing insights that drive growth. Our vision is to build the CRM platform that we always wanted: fast, intelligent, and genuinely supportive.Supported by prominent investors like Greylock, Lightspeed, and Coatue, our team previously developed Tome, a generative AI presentation tool that has gained over 25 million users. Before Tome, many of us were part of the teams behind Llama, Instagram, Facebook Messenger, Pinterest, Google, and Salesforce.About the RoleLightfield is on the lookout for a proactive Infrastructure Tech Lead to help scale our platform during a period of rapid growth and increasing customer demand. Following our successful exit from private beta, we have witnessed strong adoption from hundreds of businesses joining weekly, including larger teams leveraging our product for mission-critical operations.As we scale our customer base and data volumes surpass initial expectations, our infrastructure is entering a new phase. This role will be pivotal in ensuring that our platform remains fast, reliable, and resilient as Lightfield advances into larger enterprise applications.This is not a position focused on building a team immediately; rather, it offers a high-impact chance for an experienced infrastructure engineer to dive in, tackle core scaling challenges, and help shape the foundational architecture of our system.Your ResponsibilitiesEnhance the reliability and performance of Lightfield's infrastructure as we accelerate customer growth.Lead initiatives to minimize database latency and optimize Postgres performance for high-volume workloads.Elevate operational maturity across the stack, focusing on observability, incident response, and production readiness.Develop scalable systems and infrastructure methodologies to accommodate larger clients and growing usage.Collaborate closely with product and engineering leadership to prioritize critical infrastructure tasks at every growth stage.Contribute to defining the long-term infrastructure roadmap, with the opportunity to influence future team structure and technical direction.

At Stuut, we are revolutionizing the accounts receivable landscape for B2B companies by streamlining collections processes to be smarter and more efficient. Our innovative platform has garnered attention from finance teams across various industries, including industrials, chemicals, and manufacturing, ranging from Fortune 10 giants to emerging mid-market players. We are proud to be supported by premier investors such as a16z, Khosla, Activant, 1984 Ventures, and Page One.About the RoleVoice telecommunications play a vital role in accounts receivable operations. Our customers initiate contact via phone, agents engage in calls, and effective transfers are crucial. We are developing AI-driven agents that actively contribute to collections, cash application, disputes, and customer communications, with voice being a key component of these interactions.We are seeking a Lead Voice Infrastructure Engineer to lay the groundwork for our AI-enhanced voice initiatives at Stuut. In this position, you will collaborate closely with our engineering, product, and go-to-market teams to design and maintain the telephony infrastructure that supports high-volume phone interactions. This role merges telephony infrastructure, real-time voice systems, AI voice agents, and finance workflows.The ideal candidate will possess deep expertise in telephony, be adept at constructing distributed systems that perform reliably under production loads, and recognize the significant impact of infrastructure decisions on product outcomes. You will oversee the systems that manage call connectivity, transfer effectiveness, and business outcome measurements. As the first dedicated voice infrastructure hire at Stuut, you will be instrumental in shaping our approach.

Join Anthropic as a Staff Infrastructure Engineer focused on Cluster Infrastructure. In this role, you will have the opportunity to shape the future of AI by building and maintaining robust infrastructure systems that support our cutting-edge technologies. You will collaborate with a talented team of engineers to design scalable solutions, optimize performance, and ensure reliability across various platforms.

About UsAt Sierra, we are revolutionizing the way businesses engage with their customers by building a cutting-edge platform that harnesses the power of AI. Our headquarters is located in the vibrant city of San Francisco, with additional offices expanding in Atlanta, New York, London, France, Singapore, and Japan.Our company culture is deeply rooted in our core values: Trust, Customer Obsession, Craftsmanship, Intensity, and Family. These principles guide our actions and foster an environment where innovation thrives.Sierra was co-founded by visionary leaders Bret Taylor, who currently serves as the Board Chair of OpenAI and has a rich history with Salesforce and Facebook, and Clay Bavor, who previously led Google Labs and spearheaded initiatives like Google Lens and Project Starline.Your RoleAs a Software Engineer focusing on Infrastructure at Sierra, you will play a pivotal role in designing, constructing, and maintaining the foundational systems that empower our AI platform. Your expertise will ensure that our infrastructure is not only secure and reliable but also scalable, allowing product teams to execute their work with agility and confidence.Guarantee the reliability, scalability, and performance of our platform and LLM inference serving in response to increasing traffic demands.Develop and oversee cloud infrastructure using Terraform to create secure, scalable, and reproducible environments.Establish and manage a self-service infrastructure platform to empower engineering teams in deploying and operating services independently.Take ownership of and improve CI/CD pipelines and release management processes, facilitating rapid and reliable deployments across Sierra’s platform.Design and manage distributed systems utilizing distributed databases, retrieval systems, and machine learning models.Develop and sustain core data serving abstractions along with essential authentication and security features (SSO, RBAC, authentication controls).Effectively navigate and integrate our technology stack with enterprise customer environments in a scalable and maintainable manner.

Join Mercury as a Senior Infrastructure Engineer, where you will be pivotal in shaping the infrastructure that supports our innovative financial solutions. You will work closely with cross-functional teams to design, implement, and maintain scalable and reliable infrastructure systems. This role is ideal for individuals who thrive in a fast-paced environment and are passionate about leveraging technology to drive business success.

At Exa, we are on a mission to create a cutting-edge search engine from the ground up, designed to cater to the diverse needs of AI applications. Our team is building a robust infrastructure that enables us to crawl the internet, train advanced embedding models for indexing, and develop high-performance vector databases using Rust. Additionally, we manage a significant $5M H200 GPU cluster that powers tens of thousands of machines.The Infrastructure Team at Exa is responsible for developing the essential tools and infrastructure that support our entire system. We are looking for talented infrastructure engineers to help us scale our capabilities rapidly. Your work could involve orchestrating GPU clusters with Kubernetes, implementing map-reduce batch jobs on Ray, or creating top-tier observability tools that set industry standards.

West Monroe seeks an Advisory Lead, Infrastructure & Cloud Services for its Technology Transaction Services (TTS) practice. This position is open in Chicago, Dallas, Los Angeles, New York, San Francisco, or Seattle. Role overview This role centers on IT infrastructure due diligence for mergers and acquisitions. Projects span sectors such as Private Equity, High-Tech & Software, Healthcare, and Financial Services. The Advisory Lead assesses pre-close IT environments with a focus on public cloud, engineering, architecture, security, and overall IT strategy. What you will do Conduct IT infrastructure due diligence for client M&A transactions across several industries. Evaluate IT environments before deal closure, emphasizing cloud, security, and architecture. Identify and communicate key risks and concerns to client executives through investment summaries. Support post-close remediation projects based on due diligence findings. Contribute technical and advisory expertise to help grow the technology M&A advisory practice. Requirements Strong background in IT or public cloud engineering, architecture, security, or strategy. Experience with technology due diligence or IT assessments in M&A settings is highly valued. Ability to summarize technical risks for business stakeholders and work directly with client executives. Adaptability to work across multiple industries and new client environments. West Monroe is a consulting firm with a growing focus on technology M&A. The Technology Transaction Services team partners with clients to inform corporate development strategies and support deal execution.

OP Labs is at the forefront of developing the technology behind Optimism, the premier blockchain infrastructure provider responsible for over 65% of all Layer 2 transactions. Our open-source OP Stack allows developers and enterprises to effortlessly create scalable, secure, and customizable on-chain networks. Supported by investors such as a16z and Paradigm, we have successfully raised over $175M to propel the next wave of on-chain innovation.Role OverviewAs the Partnerships Lead for Blockchain Infrastructure, you will be instrumental in driving the development of infrastructure partnerships that are crucial for the Superchain. This role encompasses managing the complete lifecycle of vital partnerships within the OP Stack ecosystem, from identifying opportunities to closing deals and maintaining relationships with key blockchain infrastructure providers. A unique blend of commercial, strategic, and technical skills is essential to successfully navigate the dynamic crypto landscape.Key ResponsibilitiesOversee the entire lifecycle (sourcing, negotiation, integration, and partner management) for essential ecosystem infrastructure partnerships, such as:On/off ramps and payment solutions.Compliance, insurance, and risk management frameworks.Market makers, liquidity infrastructure, and select centralized exchange relationships.Partnerships related to stablecoins and fiat-rail services.Work collaboratively with the Product team to define and launch new offerings that utilize third-party technologies, particularly in areas such as Privacy and CGT.Develop and maintain the strategic roadmap for the infrastructure partner ecosystem.Communicate proactively with executive leadership regarding key ecosystem developments, potential partnership challenges, and strategic updates.QualificationsPartnership & Business Acumen:Extensive experience in managing and scaling strategic partnerships within the crypto infrastructure domain, demonstrating a successful track record in overseeing complex categories from start to finish.Exceptional commercial abilities in deal structuring and negotiation for multi-party or multi-chain agreements, effectively aligning partner economics with ecosystem goals.

Why Join GigaThe Pace: We operate at a speed that most companies only talk about. If you've been feeling stagnant in your previous role, you'll find excitement here.The Impact: Every individual at Giga contributes to meaningful work. With no bureaucratic delays, your contributions will be visible in our outputs.The Team: Join a team of top-tier professionals shaping the future of AI infrastructure. We attract high performers from the most innovative companies, drawn by the significance of our work.The Moment: AI requires power, and that's where we come in. Giga is the backbone of the AI revolution. This industry is on the verge of massive growth, and you'll be at the forefront of it.What You'll DoAt Giga, our mission is to design and manufacture data centers that support the rapid growth of AI. We are moving beyond conventional construction methods to a product-centric approach, creating and mass-producing high-performance infrastructure that meets the surging demand for computational power. As the Lead Electrical Engineer, you will be responsible for shaping the power architecture and electrical framework of these cutting-edge facilities.This is a unique chance to establish the electrical foundation of a fast-growing infrastructure company. Rather than managing just one 50 MW project, you will develop the Plan of Record (POR) for Giga Data Centers, a standardized, manufactured product that will be implemented globally.You will set the benchmark for high-density AI power delivery, designing medium and low voltage distribution systems, backup generation, and UPS solutions that can accommodate the most demanding computational tasks worldwide. The AI boom is the defining industrial challenge of our time, and you will construct the engine that drives it. Your designs will be rapidly manufactured and deployed, making a tangible impact across numerous facilities.Where You'll WorkIf you are located outside our Houston, Long Beach, Reno, or San Francisco offices, this position will be performed remotely from your home office. However, you must be willing to travel as necessary to our job sites and one of our hub locations.ResponsibilitiesDevelop and manage the electrical Plan of Record for Giga Data Centers, establishing the

About SesameAt Sesame, we envision a world where computers can interact with us in authentic, lifelike ways—seeing, hearing, and collaborating as humans do. Our mission is to create an innovative computer interface that seamlessly integrates voice agents into everyday life. Our diverse team comprises founders from Oculus and Ubiquity6 and seasoned professionals from Meta, Google, and Apple, each bringing extensive expertise in hardware and software. Join us in pioneering a future where technology feels alive.About the RoleAs a Backend Infrastructure Engineer at Sesame, you will play a pivotal role in shaping the foundational aspects of our technology stack. This position focuses on developing high-impact infrastructure, services, and tools that are broad-reaching rather than narrowly defined. You will tackle scalability and architectural challenges across various domains, including agentic workflows, speech recognition and synthesis, IoT, large-scale training, and efficient low-latency inference. If you're driven by the challenge of creating an ultra-efficient, scalable, and reliable engineering ecosystem through a blend of tooling, services, libraries, and infrastructure, this is the perfect opportunity for you.Responsibilities:Design and develop foundational infrastructure to support serving, training, and applications at Sesame.Enhance productivity for engineering teams by automating processes and creating exceptional tools.Deliver software solutions that empower product and machine learning engineers to build secure, scalable, and dependable systems from the ground up.Your responsibilities will encompass provider, service, security, and developer infrastructure, as well as the architecture and implementation of core services and libraries.

About MercorMercor operates at the cutting edge of labor markets and artificial intelligence research. Collaborating with top AI laboratories and corporations, we supply the essential human intelligence that drives AI advancement.Our extensive talent network educates state-of-the-art AI models much like teachers impart knowledge to students: by sharing insights, experiences, and contextual understanding that cannot be encoded. Currently, over 30,000 experts in our network generate more than $2 million daily.At Mercor, we are pioneering a new realm of work where expertise fuels AI progress. Achieving this ambitious vision demands a dynamic, fast-paced, and deeply dedicated team. Here, you will collaborate with researchers, operators, and AI firms at the forefront of transforming societal systems.As a profitable Series C company with a valuation of $10 billion, Mercor operates five days a week from our new headquarters in San Francisco.About the RoleIn your role as an Infrastructure Engineer at Mercor, you will be instrumental in constructing and scaling the systems that support our rapid expansion. You will ensure that our infrastructure is highly reliable, cost-efficient, and capable of accommodating surges in traffic and computational demands. Your collaboration with product, research, and operations engineers will be vital in designing scalable architectures, optimizing deployments, and enhancing observability.We are broadening our search across Infrastructure roles, including Developer Productivity Engineer, Database Engineer, and Platform Engineer. Candidates will be matched to teams after the initial screening, so we encourage applications even if your expertise is predominantly in one area.What You'll Work OnDesigning and maintaining core infrastructure across cloud environments.Creating Infrastructure-as-Code workflows to automate deployments and scaling.Enhancing monitoring, logging, and alerting systems to ensure reliability.Managing CI/CD pipelines (Github, Spacelift) for seamless deployments.Assisting in disaster recovery planning and ensuring system availability.Collaborating with product and research teams to design architectures that meet workload demands.Identifying and resolving performance bottlenecks in compute, storage, and networking.

About the RoleJoin our pioneering team at vooma as a Backend & Infrastructure Software Engineer, where you will play a critical role in shaping the technical infrastructure of a transformative company.If you are passionate about creating not only resilient systems but also the foundational architecture of a groundbreaking enterprise from the outset, this position is ideal for you.We are looking for someone who excels at crafting infrastructure that is elegant, dependable, and secure, even under high-demand scenarios. You thrive on the challenge of scaling systems that enable intelligent agents and take pride in establishing reliable foundations that others can rely on.Your Key Responsibilities Include:Design and maintain secure, scalable infrastructure tailored for AI-powered agents in production environments.Deploy and optimize AI-driven services to meet high availability and performance standards.Manage infrastructure as code, alongside cloud environments and CI/CD pipelines.Implement monitoring, observability, and alerting systems to ensure the reliability of our infrastructure.Contribute to infrastructure security and adhere to best practices.You Should Have:Experience in deploying and productionizing machine learning or AI-centric workloads.Proficiency in developing secure, scalable infrastructures on platforms such as AWS, Azure, or GCP.In-depth knowledge of backend systems, networking, and container orchestration technologies (e.g., Kubernetes).Understanding of infrastructure security principles and compliance standards (e.g., SOC2).A proactive and hands-on mindset, with a strong drive to solve challenges from start to finish.

Be part of our mission to redefine AI by shaping the narrative surrounding document understanding.Role OverviewAt LlamaIndex, our Infrastructure team lays the groundwork for our product and provides essential tools that facilitate the development, deployment, and monitoring of our code. We are tasked with designing, constructing, and scaling the core infrastructure that drives a high-capacity data platform for AI applications. We seek individuals who are passionate about creating supportive systems that enhance our engineering capabilities and contribute to our rapidly expanding product suite.Ideal candidates will have a strong background in cloud infrastructure management, navigating various scalability challenges, and enhancing the productivity of the broader Engineering team. Key traits we value in our culture include a customer-centric mindset, collaboration, diligence, and optimism. We are looking for proactive team players who are eager to help us evolve our culture as we grow.Key ResponsibilitiesCollaborate with engineering teams to develop and maintain foundational systems that empower developers and support our rapid growth.Design and execute scalable infrastructure solutions suitable for various deployment models, including SaaS, single-tenant, and private environments.Oversee and optimize cloud resources and Kubernetes clusters to ensure cost-effectiveness and high performance.Facilitate successful external customer deployments by establishing clear infrastructure guidelines and principles.Enhance the release and deployment processes to improve efficiency and reliability.Ensure compliance with applicable regulations and implement comprehensive security measures across all deployment environments.QualificationsMinimum of 5 years of engineering experience.Experience working on Platform or Infrastructure teams on substantial projects involving infrastructure components like Terraform/CDKTF, Kubernetes, Helm, testing infrastructure, release management, and observability.Proficient in optimizing cloud resource utilization.Skilled in tuning Kubernetes clusters and cloud resources for optimal performance and cost efficiency.Dedicated to cultivating LlamaIndex’s engineering culture as we expand.Ability to balance speed and pragmatism in delivering solutions.

About HappyRobotHappyRobot is pioneering the AI-native operating system for the real economy, bridging the gap between intelligence and action. By harnessing real-time truths, specialized AI workers, and orchestrating intelligence, we empower enterprises to manage complex, mission-critical operations with unprecedented autonomy.Our AI OS accumulates knowledge, optimizes processes at every level, and evolves continually. Our initial focus is on supply chain and industrial-scale operations, where resilience, speed, and ongoing improvement are paramount—liberating humans to engage in strategy, creativity, and other high-value endeavors.To explore our vision further, check out our Manifesto. To date, HappyRobot has successfully raised $62 million, including a recent $44 million in Series B funding in September 2025, with support from esteemed investors like Y Combinator (YC), Andreessen Horowitz (a16z), and Base10—partners dedicated to our mission of redefining enterprise operations. We are using this investment to build a world-class team of individuals with relentless drive, exceptional problem-solving skills, and a passion for pushing boundaries in a dynamic, high-intensity environment. If this resonates with you, we invite you to join us at HappyRobot.About the RoleWe are in search of an Infrastructure Engineer to spearhead the enhancement of our operational resilience as we scale. You will be responsible for the stability, observability, and debugging processes that ensure our systems operate seamlessly. As the primary troubleshooter for complex failures in real-time, you will design tools that transform chaos into clarity and assist in transitioning our operations from reactive to proactive.This role carries significant impact and trust, as you will influence how we approach reliability—reducing incident frequency, creating internal tools, and directly enhancing developer focus and system uptime. If you thrive on uncovering the root causes of challenging issues and fortifying systems (and teams), this is your opportunity.