Senior Scientist II/Principal Research Scientist I - Translational Program Science

AbbVie Inc.Irvine

On-site Full-time

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Experience Level

Senior

Qualifications

PhD in a relevant scientific discipline.5+ years of experience in translational research or drug development. Strong understanding of the drug discovery process and translational science. Demonstrated ability to lead projects and mentor junior scientists. Excellent communication and collaboration skills.

About the job

Join AbbVie, a global biopharmaceutical company committed to innovation and the advancement of healthcare. We are seeking a talented and experienced Senior Scientist II/Principal Research Scientist I in our Translational Program Science team. In this role, you will leverage your expertise to translate complex scientific concepts into transformative therapeutic strategies. Collaborate with cross-functional teams to drive research initiatives and contribute to the development of novel therapies.

About AbbVie Inc.

AbbVie is a research-based biopharmaceutical company that focuses on developing advanced therapies for some of the world's most complex health challenges. Our mission is to improve lives through innovative solutions that address unmet medical needs.

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Principal Research Scientist I

AbbVie Inc.

Full-time|On-site|Irvine

Join our team at AbbVie as a Principal Research Scientist I, where you will engage in cutting-edge research and development to advance our innovative therapies. This role requires a deep passion for scientific exploration and a commitment to improving patient outcomes through groundbreaking discovery.

Apr 30, 2026

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Principal Research Scientist I at AbbVie | Irvine

AbbVie Inc.

Full-time|On-site|Irvine

AbbVie is seeking a highly skilled Principal Research Scientist I to join our innovative team in Irvine, California. In this role, you will lead cutting-edge research initiatives, utilizing your expertise to drive scientific advancements that enhance patient care. You will collaborate with cross-functional teams to develop and validate new methodologies, ensuring that our research aligns with AbbVie's commitment to scientific excellence.

Apr 30, 2026

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Senior Scientist II / Principal Research Scientist I - Translational Program Science

AbbVie

Full-time|On-site|Irvine

Join AbbVie as a Senior Scientist II / Principal Research Scientist I in our innovative Translational Program Science team. We are seeking passionate and experienced scientists to drive impactful research initiatives that bridge the gap between laboratory discoveries and clinical applications. This role involves leading research projects, collaborating with cross-functional teams, and contributing to the development of cutting-edge therapies.

Apr 30, 2026

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Senior Scientist II / Principal Research Scientist I - Translational Program Science

AbbVie Inc.

Full-time|On-site|Irvine

Join AbbVie, a global biopharmaceutical company that combines advanced science with a passion for improving patients' lives. We are seeking a dedicated and experienced Senior Scientist II / Principal Research Scientist I to lead our Translational Program Science team in Irvine, California. This role is pivotal in bridging laboratory research with clinical application, focusing on the development and execution of innovative strategies to translate findings into therapeutic options.

May 1, 2026

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Principal Research Scientist - Modeling and Simulation

AbbVie Inc.

Full-time|On-site|Irvine

AbbVie is seeking a dynamic and experienced Principal Research Scientist in Modeling and Simulation to join our innovative team in Irvine, California. In this role, you will leverage your expertise to drive scientific advancements and contribute to the development of cutting-edge therapeutic solutions.

May 1, 2026

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Senior Scientist II/Principal Research Scientist I - Translational Program Science

AbbVie Inc.

Full-time|On-site|Irvine

Join AbbVie, a global biopharmaceutical company committed to innovation and the advancement of healthcare. We are seeking a talented and experienced Senior Scientist II/Principal Research Scientist I in our Translational Program Science team. In this role, you will leverage your expertise to translate complex scientific concepts into transformative therapeutic strategies. Collaborate with cross-functional teams to drive research initiatives and contribute to the development of novel therapies.

Apr 30, 2026

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Scientist I in Biologics Drug Product Development

AbbVie Inc.

Full-time|On-site|Irvine

Join AbbVie, a global biopharmaceutical company, as a Scientist I in our Biologics Drug Product Development team. In this entry-level position, you will contribute to innovative research and development projects aimed at creating life-changing therapies. You will work closely with experienced scientists in a collaborative environment, gaining hands-on experience in drug formulation and development processes.

Apr 30, 2026

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Principal Applied Scientist

Viant Technology Inc.

Full-time|$210K/yr - $250K/yr|On-site|Irvine, California, United States; Los Angeles, California, United States

WHAT YOU’LL DOJoin Viant’s pioneering Machine Learning team as we revolutionize the Ad Tech industry through advanced machine learning and AI automation. We are dedicated to replacing manual processes in digital ad creation, optimization, and measurement with autonomous, scalable systems that handle hundreds of millions of events every day. We are on the lookout for an exceptional Principal Applied Scientist who will spearhead innovative advancements in applied machine learning. In this key role, you will define our end-to-end AI strategy, craft the applied science roadmap, and develop state-of-the-art models in natural language processing (NLP), deep learning, and large-scale AI systems. Your expertise will enhance AI capabilities, driving significant business impact while cultivating a research-focused, data-driven culture at Viant.

Feb 12, 2026

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Scientist in the Innovation Lab

Tarsus Pharmaceuticals

Full-time|$97.5K/yr - $136.5K/yr|On-site|Irvine, California, United States

Hello, Tarsan!Thank you for your interest in the Scientist position at Tarsus Pharmaceuticals. Please take a moment to review the details below. If you feel this role aligns with your career aspirations, we encourage you to discuss your qualifications with your current manager and HR business partner. Should everything align, we invite you to apply, and our Talent Acquisition team will reach out to you for an interview to learn more about you.- Your Human Resources TeamAbout the RoleTarsus Pharmaceuticals is on the lookout for a talented and forward-thinking Scientist to join our dynamic Innovation Lab team. In this pivotal role, you will play a key part in the design, execution, and analysis of preclinical experiments that drive innovative eye care programs, contributing to our groundbreaking pipeline. You will also assist in the operational setup of our new in-house laboratory facilities.The successful candidate will oversee external research collaborations with Contract Research Organizations (CROs) and academic institutions while engaging in hands-on experiments within our lab. Collaborating closely with the Innovation Lab team, you will convert unmet medical needs into actionable therapeutic strategies across various ophthalmology disease areas. The ideal candidate will possess scientific adaptability, exceptional project management capabilities, and the proficiency to translate research goals into pragmatic experimental plans.Key Responsibilities:Execute experimental protocols across diverse testing methods, including phantom model testing, cell and tissue culture, and ex vivo experimentation.Facilitate ongoing communication and coordinate activities with external partners (CROs, academic laboratories) under the strategic direction of the Senior Scientist.Collaborate with external partners on in vivo ophthalmology models for efficacy, pharmacokinetics, and toxicity studies.Conduct thorough literature reviews to support ongoing projects.Analyze and summarize experimental data for internal discussions and present findings to the Innovation Lab team.Provide scientific insights and support for cross-functional initiatives as required.Perform general laboratory duties, with opportunities to assume specific responsibilities as the team expands.Stay updated with scientific and medical literature relevant to the therapeutic areas.

Feb 14, 2026

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Clinical Scientist at Balt | Irvine, California

Balt

Full-time|$160K/yr - $170K/yr|On-site|Irvine, California, United States

Balt develops medical devices for neurovascular and peripheral vascular care. With over 45 years of experience, the company collaborates with healthcare professionals and institutions worldwide. Since introducing one of the first neurovascular intervention devices in 1977, Balt has grown to 13 offices in 11 countries and continues to expand its portfolio for stroke and vascular conditions. The team is dedicated to improving the lives of more than 150,000 patients by 2026 through ongoing innovation and collaboration. What sets Balt apart Work that directly affects patient outcomes A close-knit team united by a shared mission and strong values A culture built on recognition, respect, and diversity Comprehensive support for employees in all locations Role overview The Clinical Scientist position is based in Irvine, California. This role centers on clinical research and medical writing to advance Balt’s research goals. Key responsibilities include developing clinical investigation protocols (CIPs), preparing clinical study reports (CSRs), and supporting research and development activities. The Clinical Scientist leads clinical trials from First-in-Man (FIM) through pivotal and post-market phases. Additional duties involve authoring and reviewing scientific documents and providing leadership within the clinical department.

Apr 28, 2026

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Innovative Scientist for Eye Care Development at Tarsus Pharmaceuticals | Irvine, CA

Tarsus Pharmaceuticals

Full-time|$97.5K/yr - $136.5K/yr|On-site|Irvine, California, United States

About the RoleTarsus Pharmaceuticals invites applications for a dynamic and innovative Scientist to join our Innovation Lab. In this pivotal position, you will play a key role in designing, executing, and analyzing preclinical experiments aimed at developing groundbreaking eye care solutions. You will also assist in establishing our state-of-the-art in-house laboratory facilities.Your responsibilities will include managing collaborations with external research partners, including CROs and academic institutions, while executing hands-on experiments within our laboratory. Working closely with the Innovation Lab team, you will help translate unmet medical needs into effective therapeutic strategies across various ophthalmology disease areas. The ideal candidate will possess a blend of scientific versatility, excellent project management skills, and the capability to convert research objectives into practical experimental designs.

Feb 24, 2026

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Pricing Data Scientist

iHerb

Full-time|$175K/yr - $198K/yr|Remote|United States of America - Irvine, California; United States of America - Remote / Home Office

Role Overview iHerb is looking for a Pricing Data Scientist to join the Pricing team. This role focuses on hands-on pricing analytics and measurement, supporting business decisions with data-driven insights. The position is open to candidates based in Irvine, California or working remotely from within the United States. What You Will Do Validate competitive pricing and support pricing decisions with clear analysis Measure the impact of pricing tests and experiments Analyze promotions and discounts to understand performance and effectiveness Assess price elasticity and provide actionable recommendations Translate complex pricing data into executive-ready insights for senior leadership What We Look For Strong quantitative skills and experience with predictive modeling Proficiency in SQL and Python for analytics workflows Ability to turn data findings into practical, clearly communicated recommendations Sound judgment and a proactive approach to problem-solving Comfort working independently and presenting insights to senior decision-makers Location Irvine, California Remote / Home Office (United States)

Apr 17, 2026

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Principal Technologist

ePlus inc.

Full-time|On-site|Irvine, CA

Role Overview ePlus inc. is hiring a Principal Technologist in Irvine, CA. This senior role shapes the direction of technology services across the company. The Principal Technologist leads major initiatives and guides the development of advanced solutions for clients. What You Will Do Lead technology projects from concept through delivery Advise on strategy for technology services and solutions Apply deep technical expertise to influence company direction Ensure solutions meet high standards for clients

Apr 17, 2026

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Clinical Research Coordinator

M3 USA

Full-time|On-site|Irvine

Join M3 USA as a Clinical Research Coordinator, where you will play a vital role in managing clinical trials and ensuring adherence to protocols. You will collaborate with researchers and participants to facilitate smooth operations and data collection throughout the study lifecycle.

Mar 6, 2026

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Applied Scientist II

The Trade Desk

Full-time|On-site|Irvine

Join The Trade Desk as an Applied Scientist II, where you will leverage your analytical skills to drive impactful data-driven decisions. In this role, you will collaborate with cross-functional teams to develop and implement advanced algorithms that enhance our advertising solutions. Your work will focus on transforming complex data into actionable insights, contributing to the innovation of our platform.

Apr 8, 2026

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Scientist/Chemist Position

Artech Information Systems LLC

Contract|On-site|Irvine

Join our dynamic team at Artech Information Systems LLC as a Scientist/Chemist. In this role, you will be involved in innovative research and development projects, contributing to the advancement of scientific knowledge and practical applications. This is an exciting opportunity for individuals passionate about chemistry and seeking to make a significant impact in their field.

Jul 12, 2017

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Senior or Principal Engineer - Electronic Design

dstaff

Full-time|On-site|Irvine

Join our dynamic team at dstaff as a Senior or Principal Engineer specializing in Electronic Design. In this pivotal role, you will contribute to innovative projects that drive technological advancements and enhance our product offerings. We are looking for a passionate engineer with a strong background in electronic design, who thrives in a collaborative environment and is eager to tackle complex challenges.

Aug 31, 2015

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Principal Consultant - SAP IS-U

SonSoft Inc.

Full-time|On-site|Irvine

We are seeking a talented and experienced SAP IS-U Principal Consultant to join our dynamic team at SonSoft Inc. This full-time position is ideal for individuals with a strong background in SAP IS-U solutions and a passion for delivering exceptional results. As a Principal Consultant, you will lead projects, mentor junior team members, and engage directly with clients to understand their needs and provide tailored solutions.

Jul 2, 2016

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Principal Engineer, Software Development Engineering

Western Digital Corporation

Full-time|On-site|Irvine

Join Western Digital Corporation as a Principal Engineer in Software Development Engineering. We seek a talented and innovative engineer who is passionate about software development and engineering excellence. In this role, you will lead technical projects, mentor junior engineers, and contribute to the design and implementation of cutting-edge software solutions.As a Principal Engineer, you will work closely with cross-functional teams to deliver high-quality software products. You will be responsible for defining architecture, driving best practices, and ensuring software reliability and performance.

Apr 8, 2026

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Senior Scientist II, Occupational & Environmental Toxicologist

AbbVie Inc.

Full-time|On-site|Irvine

Join AbbVie as a Senior Scientist II in the field of Occupational and Environmental Toxicology, where you will leverage your expertise to contribute to cutting-edge research and development initiatives. You will play a pivotal role in assessing the safety and efficacy of our products, ensuring compliance with regulatory standards, and protecting public health.

Apr 30, 2026

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Senior Scientist II/Principal Research Scientist I - Translational Program Science

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About the job

About AbbVie Inc.

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