Senior Application Security Engineer

About AKASAAt AKASA, we are on a mission to revolutionize healthcare through artificial intelligence. As the foremost provider of generative AI solutions for healthcare revenue cycles, we empower health systems to effectively capture and communicate the entire patient clinical journey. Our technology enables organizations to optimize their operations, allowi…

ABOUT ZIPLINEZipline is leading a logistics revolution by designing, manufacturing, and operating its own fleet of autonomous drones, along with ground-based equipment, to deliver essential and life-saving medical supplies to hospitals across multiple continents. Our mission is to ensure that every individual on Earth has immediate access to vital medical resources. Are you ready to make a global impact? Join Zipline and help us transform healthcare access for billions.ABOUT YOU AND THE ROLEAt Zipline, we create and manage drone fleets that rapidly deliver medical supplies to those in need, irrespective of their location. Our software team is working on scalable solutions that will allow for swift expansion while empowering our top-tier distribution centers to serve customers efficiently.We face security challenges that go beyond typical cybersecurity threats; they involve complex issues surrounding real-world autonomy, robotics, cloud software, and healthcare regulations. You will collaborate extensively with software, infrastructure, and autonomy teams to mitigate actual risks in our systems.We seek candidates who thrive in startup environments, exhibit versatility, and work collaboratively across various engineering disciplines. As part of our small yet impactful security team, you will have a significant role in shaping our scaling strategies.A note on our modern reality and agentic tooling:Our engineering teams are increasingly leveraging AI-powered tools to enhance productivity. However, the integration of such tools poses risks, including unmonitored access to sensitive data. You will guide Zipline in safely utilizing these technologies while ensuring they do not inadvertently alter our threat landscape.This position is hybrid; you will have regular in-person engagement at our headquarters in South San Francisco.

At Alumis Inc., we are dedicated to revolutionizing the lives of patients suffering from autoimmune diseases through precision medicine. Despite recent treatment advancements, many individuals continue to endure challenges related to immunologic conditions. Our mission is to fundamentally improve patient outcomes.We are in search of a proactive and skilled leader to join our IT team as a Senior Manager, IT, R&D Applications (Contractor). In this pivotal role, you will support essential business applications that cater to the corporate needs of our Development and Research teams, including Quality Assurance, Clinical Operations, Biometrics, Medical Affairs, and Regulatory functions. Additionally, you will play a crucial role in enterprise-level initiatives. Working closely with various stakeholders, you will manage the implementation, maintenance, and ongoing support of SaaS technologies that enhance operational efficiency and drive business success. The ideal candidate should possess a robust technical background, demonstrate excellent organizational skills, work independently, and embody a positive, solution-oriented mindset. This position reports directly to the Director of R&D Business Partner.

Oric Pharmaceuticals is hiring a Director of IT Enterprise Applications to lead the company’s approach to enterprise software. This role sits within the Information Technology team and plays a key part in shaping how technology supports daily business operations. Key responsibilities Develop and carry out strategies for enterprise application systems. Oversee projects that implement new software in support of company-wide objectives. Collaborate with teams across departments to ensure technology solutions fit business needs. Promote both innovation and efficiency through the use of enterprise applications. Location This position is based in South San Francisco.

About ZiplineAre you ready to make a significant impact? Zipline is on a transformative mission to revolutionize logistics and delivery systems across the globe. We are dedicated to addressing the most pressing access challenges by developing the first instant delivery and logistics network that serves everyone equally, no matter where they are. From supporting Rwanda's national blood delivery system and Ghana's COVID-19 vaccine distribution to facilitating on-demand home deliveries for Walmart, we are changing how goods are transported for businesses, governments, and consumers alike.The technology we utilize is intricate, yet our goal is straightforward: to create a teleportation service that delivers essentials precisely when needed. Our robotics and autonomous systems are designed to reduce carbon emissions, alleviate road congestion, and minimize fossil fuel dependency while ensuring equitable access for billions of people and strengthening the global supply chain. Join Zipline and contribute to our vision of establishing a fair and robust global supply chain for billions worldwide.About You and The RoleAs a key member of Zipline’s Flight Controls team, you will play a pivotal role in modeling, developing, and testing critical flight software systems that empower our vehicles to deliver autonomously. Our team excels at innovating solutions that allow our delivery platforms to operate seamlessly in diverse and increasingly challenging environments, ensuring equitable service to all. You will leverage a variety of analytical techniques to assess system performance and understand how design decisions impact capabilities and requirements. Collaboration across teams will be essential as you drive enhancements to our products using data derived from flight testing and our extensive fleet of customer aircraft. By engaging closely with our customers, you will gather insights to identify improvements and prioritize our next growth phases. Your success directly influences the operational effectiveness of our logistics network.

About Zipline Are you ready to make a significant impact? Zipline is committed to revolutionizing the logistics landscape. Our mission is to tackle the world's most pressing access challenges by creating, manufacturing, and operating the first instant delivery and logistics system that caters to all individuals, regardless of their location. From powering Rwanda's national blood delivery network and facilitating Ghana's COVID-19 vaccine distribution to enabling Walmart's on-demand home delivery, we are reshaping the movement of goods for businesses, governments, and consumers alike. Our technology may be intricate, but our vision is straightforward: a teleportation service that delivers essential items promptly. Through our innovative use of robotics and autonomous systems, we are not only decarbonizing deliveries but also alleviating road congestion, reducing fossil fuel usage, and combating air pollution, all while ensuring equitable access for billions and strengthening the global supply chain. About You and The Role Are you excited by the challenge of developing large, integrated electro-mechanical systems—from initial engineering builds to full-scale production and worldwide deployment? Do you thrive on tackling tasks that others deem too difficult or impossible? Are you the engineer everyone turns to for insights on building and scaling unprecedented projects? At Zipline, our work has real-world implications. Families and patients depend on us daily, and there is no margin for error. If you are passionate about leveraging your engineering skills to devise efficient and innovative manufacturing solutions, we encourage you to continue reading. We are in search of a highly skilled and proactive Senior Manufacturing Engineer to join our team. In this pivotal role, you will be tasked with designing and scaling multiple in-house final assembly lines for our aircraft, zips, docks, and various essential feeder sub-assemblies. You will ensure these lines meet escalating demand—from tens of units weekly to hundreds over the next three years—while continuously reducing costs and enhancing product quality. If you excel in fast-paced environments, enjoy managing multiple new developments simultaneously, and can swiftly align teams towards solutions, we would love to connect with you.

Lightship is hiring a Senior Engineering Technician at its South San Francisco facility. This position plays a key part in supporting the design, development, and testing of engineering projects, working closely with engineers to guide ideas from concept to completion. A hands-on approach and technical know-how are essential for keeping projects on schedule and meeting goals. Key responsibilities Support engineering design, development, and testing tasks Collaborate with engineers to address technical challenges as they arise Contribute to maintaining quality and performance standards throughout project phases What we look for Proactive approach and strong problem-solving abilities Genuine enthusiasm for engineering and technology Background in supporting engineering projects from initial stages through completion

Role Overview Cellares is seeking a Senior Operational Technology Engineer in South San Francisco, CA. This role focuses on strengthening and improving operational technology systems across the company. What You Will Do Work closely with teams from different departments to improve operational systems. Apply technical knowledge to boost the efficiency and reliability of technology supporting operations. Help identify and implement solutions that improve overall performance and support operational goals.

ABOUT ZIPLINEAre you ready to make a difference? At Zipline, we are revolutionizing the logistics of goods transportation. Our mission is to address the world's most pressing access challenges by creating, manufacturing, and operating an instant delivery system that serves all people, regardless of their location. From supporting Rwanda’s national blood delivery network and distributing COVID-19 vaccines in Ghana to facilitating on-demand delivery for Walmart and enabling healthcare providers to reach patients' homes across the U.S., we are reshaping logistics for businesses, governments, and consumers alike. Our technology blends robotics and autonomy to decarbonize delivery systems, alleviate traffic congestion, reduce fossil fuel dependency, and ensure equitable access for billions while reinforcing a more resilient global supply chain.Join us at Zipline and contribute to our vision of building a fair and robust global supply chain that benefits everyone.ABOUT YOU AND THE ROLEThe Avionics team comprises skilled hardware, software, and testing experts dedicated to designing resilient systems that power our life-saving drone delivery operations in some of the most challenging environments worldwide. We are tasked with creating aircraft avionics capable of performing optimally in diverse and harsh climatic and electromagnetic interference (EMI) conditions. As a crucial component of the overall Zipline aircraft system architecture, we prioritize high performance and reliability while minimizing weight and costs.In this role, you will collaborate with our team to deliver high-performance flight computers and tightly integrated communication and navigation systems. These avionics systems are central to our new unmanned aerial system, which aims to scale Zipline’s deliveries from 100,000 to 100 million per year globally. The success of Zipline hinges on developing avionics systems that are lightweight, cost-effective, reliable, and capable of high-volume production. This position requires rigorous engineering design and validation efforts, alongside innovative approaches to packaging, integration, fault tolerance, and validation. We seek a test engineer with a solid background in electrical engineering principles and relevant experience in manufacturing testing, design validation, system performance characterization, and certification.

Join FlyZipline as a Senior Staff RF Test Engineer and play a pivotal role in revolutionizing the logistics industry through cutting-edge drone technology. In this position, you will be responsible for designing, implementing, and executing tests to validate RF components, ensuring our systems meet the highest standards of reliability and performance.This role requires a strategic thinker with a passion for innovation and a commitment to excellence in engineering practices. You will collaborate with cross-functional teams to enhance our product offerings and contribute to our mission of delivering essential medical supplies swiftly and efficiently.

Zipline seeks a Senior Electrical Engineer to focus on Long Range Platforms at its South San Francisco location. This position centers on designing and developing electrical systems for Zipline’s delivery drones. Role overview The Senior Electrical Engineer leads efforts to create and refine the electronics that power Zipline’s long-range drone platforms. The work aims to improve both reliability and efficiency, supporting the delivery of essential goods around the world. Key responsibilities Design and develop electrical systems for drone platforms Drive improvements in reliability and operational efficiency Support technology that enables global delivery of vital supplies Location This role is based in South San Francisco, California.

Join Our Mission at ZiplineAre you ready to make a global impact? Zipline is revolutionizing the logistics industry with our groundbreaking instant delivery system. Our mission is to address the world's most pressing access challenges by ensuring equitable delivery of essential goods to every corner of the globe. From supporting Rwanda’s blood delivery network to facilitating vaccine distribution in Ghana, and even providing on-demand home delivery for major retailers, we are dedicated to transforming the supply chain for businesses, governments, and consumers alike. Our innovative use of robotics and autonomous technology not only enhances delivery efficiency but also strives to reduce carbon emissions and air pollution, creating a more sustainable future for everyone. Become a part of Zipline and help us fulfill our commitment to building a resilient global supply chain that benefits billions.Your Role at ZiplineAs a Senior Software Engineer within our dedicated team, you will play a pivotal role in developing safety-critical software for our delivery drones. Collaborating with engineers across various disciplines—such as autonomy, firmware, flight software, avionics, and simulation—you will help create the essential tools that enhance our development processes.Your responsibilities will include advancing our CI/CD systems, offering insights into PR workflows, and ensuring a seamless development experience. This role combines strategic planning with hands-on coding, allowing you to identify key investments, evaluate new tools, debug our codebase, and collaborate on critical infrastructure projects.

About ZiplineZipline stands as the world's largest and most seasoned autonomous delivery service, created to ensure equal access to essential goods for all humans, anytime and anywhere. We design, construct, and operate the most extensive autonomous logistics system globally, facilitating the rapid and reliable delivery of critical supplies. Presently, Zipline operates in four continents, executing deliveries every 30 seconds while achieving millions of successful deliveries that include blood, vaccines, medical supplies, food, and commercial products. Our clientele spans healthcare systems, governments, retailers, and global brands who depend on our services to save lives, minimize emissions, enhance economic opportunities, and provide scalable logistics solutions.Our technological prowess extends beyond drones, as we deploy integrated logistics infrastructure that fortifies supply chains, alleviates congestion, and enables instantaneous delivery, revolutionizing the accessibility of essential goods worldwide. With over 140 million commercial autonomous miles flown safely, Zipline is transforming how healthcare, consumer products, and food are accessed globally.Operating on a global scale, we seek practical problem solvers who thrive in addressing real-world challenges and rapid growth. Our team is driven by the mission to develop systems that directly impact lives and to scale the future of logistics.Why This Role MattersWe are constructing the mapping infrastructure that supports every Zipline flight. Maps Platform engineers establish the backbone that provides geographic data, features, and map-driven services to Zipline's products and operators.In this role, you will ensure that map data is fast, accurate, and reliable for both human workflows (map editors, operator dashboards, regulatory UIs) and autonomous systems (routing, onboard systems). This unique position intertwines backend, data, platform engineering, and user interface design with practical production ownership.Why This Role is UniqueBe the architect of flight intelligence. The systems you develop will directly enable how aircraft interpret and navigate their environment.Engage with massive data challenges. You will design pipelines that handle and serve large-scale geospatial datasets while adhering to stringent standards for accuracy, consistency, and availability.Experience end-to-end ownership. From raw data ingestion to production services, you will create systems critical to real-world operations.Make a cross-functional impact. Your contributions will be utilized across autonomy, routing, simulation, and operations.Leverage AI-accelerated engineering. We utilize modern AI and agentic workflows to enhance engineering velocity while upholding robust system integrity.

ABOUT ZIPLINEAre you ready to make a difference? Zipline is revolutionizing the logistics industry with our mission to overcome the world’s most pressing access challenges. We are developing the first instant delivery and logistics system that provides equal service to all individuals, regardless of their location. Our groundbreaking technology has already transformed blood delivery in Rwanda and facilitated COVID-19 vaccine distribution in Ghana. By partnering with Walmart for home deliveries and assisting healthcare providers in the U.S., we are redefining how goods move across the globe. With our eco-friendly, zero-emission service, we ensure timely delivery of essential supplies when they are needed most.Join us at Zipline and play a pivotal role in creating a fairer, more resilient global supply chain that serves billions.ABOUT YOU AND THE ROLEAre you passionate about applying your technical expertise to tackle real-world challenges? Do you excel in environments that grant you ownership, creative freedom, and complex problems to solve? If so, we invite you to become part of our Field Systems Engineering team at Zipline—where your contributions directly impact lives every single day.Since launching our long-range drone platform in Rwanda in 2016, we have enabled rapid, dependable delivery of critical medical supplies to remote areas, boasting a fixed-wing design that can travel over 200 km on a single charge. Our drones have already made a significant impact, helping new mothers in Rwanda and delivering antivenom to snake bite victims in Ghana, serving millions by delivering thousands of life-saving products daily.The Field Systems Engineering (FSE) team operates at the nexus of Engineering and Operations. We ensure that our designs are safe, robust, and reliable because lives depend on them. As a Senior Embedded Software Engineer within the FSE team, you will be instrumental in enhancing the performance and reliability of our long-range drone systems.In this role, you will collaborate with various cross-functional engineers and flight operators to identify challenges in how our software supports daily operations for our Platform 1 vehicle deployed globally. You will lead investigations into anomalies, establish data-driven requirements, and spearhead execution of improvement projects aimed at increasing system reliability and ease of maintenance.

About Us: Calico Life Sciences LLC, a subsidiary of Alphabet, is at the forefront of research and development, focusing on understanding the biology of human aging through advanced technologies and innovative model systems. Our mission is to leverage this knowledge to create interventions that promote longer, healthier lives. With cutting-edge technology labs, a commitment to curiosity-driven scientific discovery, and a dynamic drug-development pipeline in collaboration with academic and industry partners, Calico is a vibrant environment for catalyzing medical breakthroughs. Role Overview: We are on the lookout for a Senior Data Engineer to become a key member of our collaborative Engineering team and lead the establishment of the Drug Discovery Data Engineering group. The ideal candidate will be an enthusiastic team player, meticulous, highly organized, and adept at navigating intricate data, software, and scientific challenges. In this role, you will serve as a crucial technical liaison among our Medicinal Chemistry, Automation, Machine Learning, Assay Technology, and Protein Sciences teams. You will oversee projects from initial requirements through to production deployment, engineering high-performance data systems that integrate with our molecular databases (CDD Vault), inventory systems (Mosaic), electronic lab notebooks (Benchling), our internal data warehouse (BigQuery), and our proprietary AI platform. As the inaugural hire for this team, your contributions will be instrumental in shaping data flows, developing web applications for stakeholder engagement, and establishing a progressive engineering culture in this vital growth sector. Key Responsibilities: Project Leadership: Collaborate with scientists across Assay Technology, Medicinal Chemistry, and Protein Sciences to gather requirements, design solutions, and implement production-grade software that enhances data movement and analysis. System Integration: Create and deploy effective integrations between internal pipelines and third-party platforms, particularly involving the CDD molecular database, Mosaic inventory systems, and Benchling ELN. Data Flow Optimization: Develop and refine data flows organization-wide (e.g., facilitating seamless data transitions from Machine Learning to Protein Sciences to Assay Technologies) to expedite the drug discovery feedback loop. Full-Stack Development: Build data systems and internal web applications (utilizing React and Python) to empower stakeholders to review, visualize, and communicate complex scientific data effectively. Mentorship & Leadership: Act as a senior technical advisor within the broader Engineering team.

Maze Therapeutics applies precision medicine to address both common and rare diseases. The Machine Learning Application Engineer II role is based in South San Francisco and focuses on building and improving production-ready solutions that advance drug discovery efforts. Role overview This position centers on designing and developing data and machine learning infrastructure that supports different stages of drug discovery, from early research through lead optimization and development. The work involves refining existing systems to improve reliability and scalability while ensuring alignment with scientific objectives. What you will do Design and develop infrastructure for data and machine learning to support multiple phases of drug discovery. Enhance current systems to improve reliability, scalability, and scientific relevance. Apply FAIR data principles to maintain strong standards in data management and engineering. Collaborate with scientific and engineering teams to deliver solutions that enable data-driven research. Reporting structure This role reports to a Senior Data Engineer.

Role overview FlyZipline is seeking a Senior Mechanical Engineer to join the Long Range Platform team in South San Francisco, California. This role centers on designing, developing, and implementing mechanical systems that support advanced logistics platforms. The work directly impacts the reliability and efficiency of drone technology used to deliver medical supplies to remote locations.

Cellares is on the lookout for an innovative and dynamic Information Security Lead to become the cornerstone of our Information Security program. As the inaugural security hire, you will play a pivotal role in shaping our InfoSec strategy while also engaging in hands-on technical execution. Your primary responsibility will be to enhance and strengthen our security posture, lead a diverse team across various locations, and ensure compliance with essential regulatory standards, including 21 CFR Part 11, SOC 2, and ISO 27001. This multidisciplinary role requires collaboration with multiple departments to drive policy and governance initiatives. Ideal candidates thrive in a fast-paced, mission-driven environment and are ready to embrace a variety of challenges as Cellares expands.

Senior Software Engineer - Motor Control SystemsJoin our team in South San Francisco!About ZiplineAre you ready to make a significant impact? At Zipline, we are revolutionizing the logistics and delivery landscape. Our mission is to tackle the world’s most pressing access issues by developing an innovative instant delivery system that serves everyone equally, regardless of location. From supporting Rwanda’s national blood delivery service to facilitating Ghana’s vaccine distribution, and providing on-demand deliveries for Walmart, our work is transforming the logistics paradigm. Our technology, which merges robotics and autonomy, is leading the charge towards a sustainable future by decarbonizing delivery, alleviating road congestion, and minimizing pollution, while ensuring equitable access for billions and fostering a resilient global supply chain.Be a part of Zipline’s commitment to creating a more equitable and resilient global supply chain. Your Role and ResponsibilitiesAs a Senior Software Engineer focused on Motor Control Systems at Zipline, you will play a pivotal role in developing high-performance motor controller firmware for our proprietary motor controllers. Collaborating closely with electrical engineers, design teams, flight software developers, and operational test teams will be integral to your work. Our collaborative engineering environment allows you to learn from a multidisciplinary team while rapidly implementing features that directly enhance the delivery experience.Our firmware development primarily utilizes C++, with Rust and Python for tooling deployed in our field systems. Our team employs hardware- and software-in-the-loop testing to validate new features and conduct regression tests on existing functionalities. You will analyze extensive datasets from our test operations to inform data-driven engineering decisions and prototype new algorithms. Analysis will be conducted using Matlab, Julia, or Python to validate the performance of your control designs, including executing Monte Carlo simulations to ensure accuracy in complex dynamics.

About ZiplineAre you ready to make a significant impact? At Zipline, we are committed to revolutionizing the logistics of goods delivery across the globe. Our mission is to address the world's most pressing access issues by designing, manufacturing, and operating an instant delivery system that ensures equitable access to all, no matter their location. From supporting Rwanda's national blood delivery network and facilitating Ghana's COVID-19 vaccine distribution to enabling Walmart's on-demand home deliveries and helping healthcare providers reach patients directly in the U.S., we are reshaping logistics for businesses, governments, and consumers alike. Our innovative technology encompasses robotics and autonomous systems, aimed at decarbonizing delivery, alleviating road congestion, and minimizing fossil fuel consumption and pollution, all while fostering a more resilient global supply chain.Join us at Zipline and be part of our pledge to create an equitable and robust global supply chain that serves billions.