Lead Software Engineer

Systems Technology Research (STR) is actively seeking skilled Senior Lead Software Engineers to become integral members of our innovative cyber and networking team. We are dedicated to advancing cutting-edge technologies that significantly enhance national security. Our team is at the forefront of communications technology, operating across all networking la…

Systems Technology Research (STR) is seeking a Lead Principal Software Reverse Engineer with a deep passion for investigating and analyzing vulnerabilities within cyber-physical systems. Join a dynamic and multidisciplinary team of researchers and engineers focused on pioneering technologies that make a substantial impact on national security. This role provides a unique opportunity to work at the intersection of computing and physical systems. We value the diverse skills, experiences, and perspectives that each employee brings, which are crucial for delivering innovative solutions to our clients. Note: This position requires onsite work and an Active Top Secret (TS) clearance.

Join STR as an Emulation Tooling and Modeling Software Engineer, where you'll collaborate within a multidisciplinary team of skilled researchers and engineers to develop pioneering technologies that significantly enhance our national security. This role presents a unique opportunity to bridge the gap between computational systems and real-world physical environments. At STR, we value the diverse skills and perspectives of our employees, recognizing that these attributes drive our ability to deliver innovative solutions to our clients. If you find your expertise aligns with our needs, we encourage you to apply!As an Emulation Tooling and Modeling Software Engineer, you will be adept in one or more high-level programming languages (C/C++, Python) essential for creating the foundational tools that facilitate the development of emulation models for intricate cyber-physical systems. Ideal candidates will possess experience in reverse engineering embedded instruction set architectures (e.g., ARM, PPC) and a strong motivation to design emulator tools for a wide range of targets. Key responsibilities include developing tools such as operating system handlers, bare metal firmware emulation, and virtual device simulations to support the emulation of relevant signal processing and control system components and algorithms. These components will be prototyped using time and event-driven simulations, implemented on real-time hardware systems.You will also contribute to the model development for sensors, actuators, dynamics, and environmental factors based on first principles, empirical data, and existing documentation/hardware/software artifacts. Ensuring the quality and validity of these models will require unit testing and effective integration into larger system simulations. Familiarity with developing modular code that adheres to well-defined component message/protocol interfaces is crucial. Experience with both hardware and software elements, especially at the software/hardware interface (e.g., serial, USB, data acquisition subsystems, and device drivers), is highly beneficial.

About Azurity Pharmaceuticals Azurity Pharmaceuticals develops specialty medications for patients whose needs are often underserved. The company’s commercial portfolio and late-stage pipeline cover areas such as cardiovascular, neurology, endocrinology, gastrointestinal, institutional, and orphan diseases. Azurity works with an integrated team and a broad network of partners to expand its range of products and reach more patients. Millions of people benefit from Azurity’s focus on unique, high-quality therapies. Learn more at www.azurity.com. Workplace and Values Azurity is committed to building an inclusive workplace and is proud to be an Equal Opportunity Employer. The team values scientific rigor, quality, and a patient-first mindset. Integrity, creativity, and dedication are essential traits for success here.

At Systems Technology Research (STR), we are committed to making the world a safer place by advancing technology to address critical national security challenges. Our Cyber Division is at the forefront of developing innovative solutions, focusing on integrating the right technology to combat emerging cyber threats. We emphasize impactful results, craftsmanship, and collaboration as we tackle some of the toughest cyber challenges facing our nation.As a Senior Embedded Software Engineer at STR, you will join a dynamic, multidisciplinary team of researchers and engineers dedicated to pioneering vulnerability research technologies. Our initiatives bridge the gap between digital and physical realms by developing models of physical systems, identifying vulnerabilities in interfaces, and reverse engineering software.

Spear Bio, established in 2021, is a dynamic and well-funded biotech start-up located in Woburn, Massachusetts. Our innovative technology, Successive Proximity Extension Amplification Reaction (SPEAR), presents a groundbreaking wash-free immunoassay platform that offers unmatched sensitivity. We are committed to transforming early disease diagnosis and monitoring by delivering scalable, ultra-sensitive solutions that ensure exceptional accuracy in detecting low-abundance biomarkers. This empowers clinicians and researchers to enhance patient outcomes and promote global health.Scientist/Senior Scientist - Assay Development:In this critical role, the Scientist/Senior Scientist will drive Spear Bio's assay development efforts for our cutting-edge ultrasensitive immunoassays. Reporting to the Senior Director of Assay Development, this position will work closely with both Platform and Product Development teams. The ideal candidate will possess a robust history of developing and refining immunoassays tailored for both research and clinical applications, specifically aimed at detecting low abundance protein biomarkers associated with neurodegenerative diseases.This position requires onsite presence at our Woburn, MA laboratory five days a week.Responsibilities:Create a suite of ultrasensitive, ELISA-based immunoassays through all stages of product development, including screening, optimization, feasibility, and validation. This involves meticulous planning, design, and execution of laboratory work related to antibody selection, reagent conjugation, buffer optimization, and assay validation across various sample matrices for research and clinical applications.Conduct in-depth scientific research on immunoassay design and troubleshooting methodologies, focusing on factors such as dynamic range, limit of detection, spike and recovery, precision, accuracy, and assay linearity. Utilize Design of Experiments (DOE) and data analysis techniques to adhere to project timelines.Compile, document, and critically assess reports throughout the assay development process in preparation for product launches.Collaborate with cross-functional teams to create marketing collateral, internal reports, conference presentations, and posters, leveraging data from immunoassay development.Provide mentorship to junior scientists and offer strategic guidance on ongoing projects.

About Our Team At Systems Technology Research (STR), our Analytics & C2 Division is dedicated to pioneering innovative technologies that address complex national security challenges through advanced analytics. Our team is composed of enthusiastic and highly skilled engineers and scientists holding advanced degrees in fields such as engineering, computer science, mathematics, physics, and data science. Together, we leverage our expertise and creativity to transform groundbreaking concepts into fully realized implementations, enhancing the success of our clients' missions. The Signals Exploitation and Tracking (SET) Group within the Analytics Division specializes in utilizing machine learning, statistical methods, estimation techniques, and information theory algorithms to excel in target tracking, signals exploitation, and effective resource management. Your Role As a Senior Algorithm Developer, you will spearhead the development of cutting-edge technologies aimed at advancing target tracking and predictive capabilities. Your responsibilities will include creating and executing algorithms, designing and conducting comprehensive experiments and analyses, collaborating with interdisciplinary project teams, and engaging directly with clients. You'll work with intriguing datasets, devise innovative algorithmic methodologies, and tackle significant, unique challenges for our clients. This position is primarily based in our Woburn, MA office, and we invite you to join our team on-site.

Join Our Team as an OBIEE Developer!We are seeking an experienced OBIEE Developer with a strong background in Oracle EBS financial systems. In this role, you will create and validate reports from the ground up, ensuring accuracy and effectiveness in delivering key insights.Key Responsibilities:Develop and design comprehensive reports using OBIEELeverage your knowledge of Oracle EBS financial modules, including Accounts Receivable (AR), Accounts Payable (AP), Fixed Assets, and Revenue ManagementCommunicate effectively within teams to understand reporting requirements and deliver solutions

Spear Bio, established in 2021, is an innovative and well-capitalized biotechnology startup based in Woburn, Massachusetts. Our cutting-edge technology, Successive Proximity Extension Amplification Reaction (SPEAR), represents a groundbreaking wash-free immunoassay platform that delivers unmatched sensitivity. We are committed to transforming early disease diagnosis and monitoring, providing scalable and ultra-sensitive solutions that achieve unparalleled accuracy in detecting low-abundance biomarkers, thereby empowering clinicians and researchers to enhance patient outcomes and drive global health advancements.We are currently seeking a Scientist or Senior Scientist with a robust background in immunoassay Product and Process Development. The ideal candidate will be instrumental in the development, optimization, and commercialization of next-generation immunoassay products and processes. As a subject matter expert, you will address assay troubleshooting, drive continuous improvement, and ensure the robustness, reproducibility, and scalability of Spear Bio's offerings.

Why Join Us? Become a champion for patients with rare diseases. At Ultragenyx, we are committed to taking meaningful action to improve the lives of patients and our employees. Our vision is to innovate the future of rare disease medicine by venturing into areas that other biopharma companies may overlook. We aim to challenge conventional methods and create a transformative model that enhances patient access to life-altering therapies. We achieve this by adhering to scientific principles, employing a rapid development approach, producing affordable innovative medicines, and fostering a collaborative ecosystem to reach patients in the most impactful ways. Our devotion to patient care extends to our employees, making our culture a vital pillar of Ultragenyx. We strive to cultivate a supportive and inclusive environment that promotes profound learning and growth, allowing our team members to flourish both personally and professionally. Our ultimate goal is to be an organization our families, friends, and future generations would be proud to join. If you are eager to make a meaningful impact, excel in your career, and experience significant personal and professional growth, we invite you to become a part of our team.Position Summary:Ultraimpact – Contribute significantly to those who need it the most.Work Model: Core Lab & Operations: This role typically requires that the majority of work be conducted on-site and will adhere to specific safety protocols during the pandemic.Responsibilities:We are looking for an enthusiastic undergraduate or graduate student to join our AAV Purification Process Development team. The selected candidate will assist with laboratory and data-driven tasks that are directly involved in commercial manufacturing, process development, and clinical compatibility studies. This position provides hands-on experience in gene therapy purification process development, exposure to GMP-aligned development workflows, and the chance to acquire industry-relevant skills in various purification units.

Spear Bio, established in 2021, is an innovative and well-capitalized biotech startup located in Woburn, Massachusetts. Our cutting-edge technology, Successive Proximity Extension Amplification Reaction (SPEAR), represents a novel wash-free immunoassay platform that delivers unmatched sensitivity. We are committed to transforming early disease diagnosis and monitoring through scalable, ultra-sensitive solutions that ensure exceptional accuracy in quantifying low-abundant biomarkers, thereby enhancing patient outcomes and advancing global health.Position Overview:We are on the lookout for high-achieving Business Development Managers to expand our portfolio of ultra-sensitive Immunoassays within the Life Sciences and CRO sectors. Candidates should be based in the Northeast, preferably Greater Boston, and possess a robust network in neurodegenerative disease research among Big Pharma, Biotech firms, CROs, and academic institutions across Greater Boston and other key East Coast regions.Primary Responsibilities:Conduct compelling sales presentations to prospective clients, effectively communicating the value proposition of Spear Bio.Exhibit a thorough understanding of the Neuroscience market and technology adoption, instilling confidence in Spear Bio’s customers about our superior, best-in-class solutions.Drive kit sales by providing tailored instrument and Assay Service solutions to foster market adoption and revenue growth.Manage a pipeline of opportunities under the guidance of senior Business Development Managers.Oversee all customer logistics and follow-ups, including demos, information sharing, and addressing technical inquiries to effectively engage customers.Leverage your existing network of high-level scientific contacts in Big Pharma, Biotech, CROs, and academia, alongside your insight into IVD markets, including LDTs.Support our strategic distribution partnership with Bio-techne, the leader in Immunoassays, and utilize their network to promote Spear Bio’s solutions. Aid Bio-techne in achieving their distribution goals by providing guidance and training in funnel management and understanding key business requirements to meet financial targets for both companies.Consistently exceed quotas and revenue targets, driving market share growth in your designated territory.

The Real-time Architectures, Integration, and Demonstration (RAID) Group at Systems Technology Research focuses on transforming early-stage algorithms into real-time software solutions. The team is known for advancing open architecture and plays a central role in integrating new capabilities for experimentation, testing, and deployment. Role overview The Chief Scientist leads technical teams developing Open Architecture solutions for real-time environments. This role manages the transition of algorithms from concept to execution, supports marketing efforts, and provides mentorship to junior engineers. Key responsibilities Guide teams in designing, developing, and deploying open architecture solutions for sensor systems. Optimize system architectures for real-time, resource-constrained environments with strict latency requirements. Design communication infrastructure and data flows for distributed processing systems. Support open system integration, including hardware-in-the-loop testing and seamless integration across multiple architectures, external systems, and hardware platforms. Conduct design reviews and technical risk assessments to ensure compliance with open architecture standards. Mentor junior and mid-level engineers, sharing technical expertise and guidance. Prepare technical reports, develop briefings, and present findings to sponsors and senior management. Collaborate with customers, program managers, and stakeholders to define technical requirements. Lead proposal efforts, including defining technical approaches, estimating costs, and creating white papers. Work closely with algorithm developers, systems engineers, RF hardware engineers, and integration teams across programs. Stay informed on emerging technologies and best practices in open architecture development and deployment. Travel up to 20% for client meetings, integration events, and field demonstrations. Requirements Eligible for a Top Secret security clearance (U.S. citizenship required). BS, MS, or PhD in Computer Science, Computer Engineering, Electrical Engineering, or a related field, with 10-15+ years of relevant experience depending on degree. Proficiency in at least two technical areas (areas not specified in the source). Location: Woburn, MA

As a Research and Development Technician, you will play a vital role in conducting non-clinical (in vitro) drug metabolism and drug-drug interaction studies for our pharmaceutical clients. Your work will adhere to the established study protocols and the company’s standard operating procedures (SOPs). Key responsibilities include equipment setup, calibration, and operation; preparation of test articles and solutions; data collection; and thorough documentation (both written and electronic) in compliance with our operating procedures. You will also engage in troubleshooting technical problems and conduct preliminary data analysis for review by the Study Director, as well as evaluate results for reporting purposes.Essential qualifications include a solid understanding of cell culture basics, laboratory safety protocols, and aseptic techniques. A strong background in cellular and molecular biology or biochemistry is preferred. Proficiency in word processing and spreadsheet applications on PC-based systems for data analysis is essential.The ideal candidate will be a team player who demonstrates initiative in identifying and developing solutions independently. You should be capable of managing multiple projects to meet deadlines and exercise sound judgment in protecting company confidential and proprietary information. Establishing positive relationships with both internal and external contacts is crucial, alongside possessing strong communication and writing skills.

The System Development Division (SDD) is dedicated to enhancing National Defense capabilities by implementing mission-driven strategies to create cutting-edge technology systems. Our focus is on developing sustainable, reliable, and cost-effective solutions that meet the needs of our clients and function effectively in operationally relevant environments. SDD embraces a comprehensive approach to the entire lifecycle of our solutions, from conception and architectural design to development and deployment, leveraging innovative technologies to deliver pioneering systems.We are currently looking for a skilled Lead Firmware Engineer with a robust understanding of digital signal processing, particularly in radar applications. This role involves implementing intricate system algorithms and interfaces in FPGAs for Radar and Electronic Warfare (EW) systems, covering all project stages from initial concept creation to design, prototyping, development, testing, and production transition. You will be responsible for executing, testing, and validating designs through simulation and laboratory testing, which may encompass signal processing across wide frequency bands, high data rate interfaces, and complex control logic.Moreover, you will play a key role in assessing current and future system capabilities, identifying enhanced applications and techniques, and proposing effective solutions. This position demands collaboration with multidisciplinary teams, supporting development and testing activities, alongside strong technical proficiency in relevant technologies. Excellent interpersonal, communication, and technical skills are essential, as you will need to effectively convey information to various levels of management and team members. Ideal candidates are self-motivated, detail-oriented, and possess strong written and verbal communication abilities.

Join STR as a Senior Systems Integration and Test (I&T) Engineer in Woburn, MA, where you will play a pivotal role in the integration and testing of cutting-edge multi-function RF systems. You will collaborate with development teams and domain experts to design innovative test environments and ensure the seamless integration of hardware and software components. Your expertise in automated testing tools, test plans, and system design will be crucial in delivering high-quality defense solutions. This position provides an exceptional opportunity to engage in hands-on testing and contribute to the lifecycle of advanced technology systems while adopting Digital Engineering practices and Model-Based Systems Engineering (MBSE) methodologies.

Sirtex Medical Limited is hiring a Director of Product Engineering to oversee the development and enhancement of class II and III medical devices. This leadership position manages the engineering team, with an emphasis on maintaining product safety and effectiveness at every stage of design and development. What you will do Direct engineering projects for both new and existing class II and III medical devices Collaborate with R&D, quality assurance, and regulatory affairs to move products from concept through to market launch Define and uphold engineering direction, ensuring all products meet required safety and efficacy standards Promote technical excellence and foster ongoing improvement within the team Location This role is based in Woburn.