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AI Scientist - BioMedical AI

Xaira TherapeuticsSouth San Francisco, California, United States
On-site Full-time $150K/yr - $240K/yr

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Experience Level

Experience

Qualifications

Key ResponsibilitiesDesign, train, and refine foundational models specifically tailored to perturb-seq and other single-cell datasets. Build pipelines for preprocessing, normalization, and integration of extensive single-cell and perturbation data. Utilize machine learning and AI methodologies to model cellular responses to perturbations, identifying causal biological insights. Work in collaboration with experimental biologists to ensure alignment between computational methods and experimental design, as well as discovery objectives. Develop multimodal integration techniques across transcriptomic, epigenomic, and proteomic single-cell readouts. Publish methodologies and findings in prestigious scientific journals and represent the company at conferences. QualificationsPhD or equivalent in Computational Biology, Computer Science, Bioinformatics, or a related field. Extensive expertise in single-cell data analysis, particularly with perturb-seq. Hands-on experience with foundational models or large-scale self-supervised learning techniques (e.g., transformers, variational autoencoders). Proficient coding skills in Python, familiar with ML frameworks (PyTorch/TensorFlow), and single-cell analysis tools (Scanpy, Seurat). Experience in developing scalable machine learning methods for large biological datasets. Preferred QualificationsBackground in working with clinical data or translational research. Strong communication skills and ability to work collaboratively in a team-oriented environment.

About the job

About Xaira Therapeutics

Xaira Therapeutics is a cutting-edge biotechnology startup dedicated to harnessing the power of artificial intelligence to revolutionize the fields of drug discovery and development. Our mission is to innovate generative AI models that facilitate the design of protein and antibody therapeutics, paving the way for effective treatments against traditionally challenging molecular targets. In addition, we are advancing foundational biological models to enhance target identification and patient stratification. These pioneering technologies are designed to continuously uncover novel therapies and boost the success rates in drug development. Our headquarters are strategically located in the San Francisco Bay Area, Seattle, and London.

About the Role
We are seeking an AI Scientist to become an integral part of our team at the convergence of machine learning and single-cell biology. In this pivotal role, you will focus on the development and application of foundational models to large-scale perturb-seq and single-cell datasets, revealing new biological mechanisms and therapeutic potentials. You will be responsible for designing scalable machine learning architectures that can extract insights from high-dimensional perturbation data and integrate across multi-omic modalities.

About Xaira Therapeutics

Xaira Therapeutics is at the forefront of biotechnology innovation, utilizing artificial intelligence to reshape the landscape of drug discovery and development. With a commitment to excellence and a team of expert scientists, we strive to unlock groundbreaking treatments and improve patient outcomes.

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