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Principal Scientist jobs in San Diego· Page 3

Results 41–60 of 69 for “Principal Scientist” in San Diego.

69 jobs found

41 - 60 of 69 Jobs
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iambic therapeutics logo
Full-time|On-site|San Diego HQ

JOB SUMMARYiambic therapeutics is on the lookout for a talented and motivated Analytical/Bioanalytical Scientist specializing in chromatography-based purification to enhance our drug discovery initiatives. The chosen candidate will be instrumental in facilitating high-throughput purification and assay workflows, supporting a weekly design-make-test-analysis …

Feb 27, 2026
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Genesis Molecular AI logo
Full-time|On-site|San Diego, CA

At Genesis Molecular AI, we are creating an elite team of experts in computational chemistry to transform the landscape of drug discovery through advanced machine learning and biophysical simulations. We invite a Senior Computational Aided Drug Discovery (CADD) Scientist to join us in our mission, collaborating closely with scientists in our advanced wet lab and our distributed teams in computational chemistry across the United States.Key ResponsibilitiesEmploy a mix of industry-standard and proprietary AI-driven CADD tools to steer small molecule drug discovery initiatives across a diverse array of targets, including innovative targets with limited chemical history.Utilize techniques such as virtual screening, molecular simulations, and ADMET prediction to facilitate critical decision-making during drug discovery.Work closely with medicinal chemists on molecular design and the creation of tailored computational methodologies for specific projects.Serve as a liaison across teams, effectively bridging communication between our computational and medicinal chemistry departments to ensure smooth information exchange and collaborative strategies.Thrive in a fast-paced environment that encourages innovation and rapid iteration.QualificationsPhD in Computational Chemistry, Structural Biology, or a related discipline. Candidates with a PhD in organic or medicinal chemistry and substantial laboratory experience transitioning into industry roles in CADD are also encouraged to apply.Extensive knowledge of structure-based drug design and protein-ligand interactions.Expertise in using industry-standard CADD tools, including MOE, PyMOL, and Schrodinger Suite.A minimum of 2 years of experience in the pharmaceutical or biotech industry as a CADD scientist, with practical involvement in active drug discovery projects.While onsite presence at our San Diego lab is preferred for collaboration, we are open to considering remote team members as well.What We OfferAttractive SalaryComprehensive Health Care Plans (Medical, Dental, and Vision fully covered for employees)An opportunity to work in a pioneering environment with the latest technologies in drug discovery.

Oct 28, 2025
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Ramboll logo
Full-time|$178K/yr - $222K/yr|On-site|Los Angeles

Are you ready to enhance your career in a dynamic, inclusive, and supportive environment? Do you want to be part of a company that is dedicated to creating impactful change for its employees, clients, and the community? If you are passionate about fostering sustainable practices that benefit both society and the environment, we have the ideal opportunity for you!Join our Environment and Health division as a Principal Consultant and collaborate with our talented team to help bridge the gap towards a sustainable future.Your Role:We are on the lookout for a Principal Consultant in the San Diego area to bolster our local office's growth. Ideal candidates will possess a consulting background in site investigation and remediation, due diligence, compliance, or air quality management. As our new Principal, you will become an integral part of our team, addressing a wide spectrum of environmental challenges faced by our clients. Bring your expertise in Environmental Consulting and Business Development to the forefront as you work towards innovative and sustainable solutions. You will serve as a reliable advisor to clients, delivering technical and business insights while collaborating with our skilled professionals in areas like due diligence, site remediation for contaminated materials, real estate redevelopment, hazardous waste management, and compliance with environmental regulations. A strong emphasis will be placed on business development, ensuring a steady flow of projects that support the office's expansion. Typically, Principals are expected to generate enough business to sustain 2-3 full-time staff members and guide clients throughout the project lifecycle. Additionally, you will be responsible for managing projects effectively, ensuring timely, profitable, and high-quality delivery. We value your commitment to mentoring the next generation of leaders, empowering them to excel and build fulfilling careers.Your Responsibilities:Identify and pursue new business opportunities while fostering client relationships;Oversee project management, client interaction, team leadership, and regulatory agency engagement;Conduct critical reviews of project requirements, applicable environmental regulations, and communicate findings effectively;Deliver projects that may involve site visits, preparation, and review of deliverables;Act as a role model, ensuring the health, safety, and security of our team.Your Team:As a member of our Environment and Health team, you will collaborate with passionate individuals dedicated to solving client challenges and making a positive impact.

Mar 4, 2026
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Becton, Dickinson and Company logo
Senior Scientist - Molecular Point-of-Care

Becton, Dickinson and Company

Full-time|On-site|San Diego

Join Our Mission to Advance Global Health!Becton, Dickinson and Company (BD) is a leading global medical technology company dedicated to advancing the world of health. We strive to enhance medical discovery, diagnostics, and the delivery of care. With over 65,000 employees across the globe, we are committed to tackling some of the most pressing health challenges worldwide. As the Health Economics and Outcomes Research Lead, you will report to the Director of Scientific Affairs & Clinical Evidence within our Medical Affairs team. In this critical role, you will be tasked with developing and executing agile HEOR strategies in collaboration with both global and regional teams. Your expertise will drive impactful research and ultimately improve patient outcomes.

Feb 8, 2022
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Sonsoft Inc. logo
Full-time|On-site|San Diego

Join Sonsoft Inc. as a Principal Consultant specializing in Salesforce solutions, where you will leverage your expertise in functional or technical sales to drive innovative solutions for our clients. You will collaborate with cross-functional teams to design, implement, and optimize Salesforce applications that enhance business processes and improve customer experiences.Your role will involve understanding client requirements, providing strategic guidance, and ensuring the successful delivery of Salesforce projects. This is an exciting opportunity to be part of a dynamic team that values innovation and excellence.

Mar 13, 2017
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Capricor Therapeutics logo
Full-time|On-site|San Diego, CA

Capricor Therapeutics (NASDAQ: CAPR) is a pioneering biotechnology company focused on developing groundbreaking cell and exosome-based therapies for rare diseases. Our flagship product, Deramiocel (CAP-1002), is currently in late-stage development targeting Duchenne muscular dystrophy. Additionally, we are utilizing our innovative StealthX™ exosome platform to enhance targeted delivery systems and advance vaccinology initiatives. Each of our programs embodies our dedication to pushing scientific boundaries and providing transformative treatments for patients and their families.The Analytical Development Scientist plays a vital role as a senior technical contributor within our Analytical Development team. This position involves leading the development, optimization, and validation of sophisticated analytical methods that support our cell therapy and biologic products. Operating with a high level of independence and scientific acumen, the Scientist will oversee cross-functional projects, steer assay strategies, and ensure compliance with regulatory standards and program timelines. This role is crucial for making technical decisions, facilitating the progression of projects from initial development through to commercialization, and mentoring team members while fostering robust collaboration across departments.

Apr 2, 2026
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Capricor Therapeutics logo
Full-time|On-site|San Diego - SD1

About Capricor Therapeutics Capricor Therapeutics (NASDAQ: CAPR) is a biotechnology company focused on developing cell and exosome-based therapies for rare diseases. The company’s lead product, Deramiocel (CAP-1002), is in late-stage development for Duchenne muscular dystrophy. Capricor’s StealthX™ exosome platform supports new approaches in targeted delivery systems and vaccinology, with a mission to advance science and deliver new treatments for patients and families facing serious conditions. Role Overview: Quality Control Scientist, Analytical Controls This role is based in San Diego (SD1). The Quality Control Scientist, Analytical Controls, develops, qualifies, and manages analytical control materials for QC assays. The scientist will generate and maintain both positive and negative controls, design and execute analytical studies, and troubleshoot or improve analytical methods used in QC testing. Key Responsibilities Develop and qualify analytical control materials for use in QC assays. Manage the lifecycle of control materials, including ongoing maintenance and documentation. Design and conduct analytical studies to support QC operations. Troubleshoot and refine analytical methodologies as needed for QC testing. Ensure reliability, reproducibility, and regulatory compliance of QC assays. Provide scientific guidance on assay control strategies. Collaborate with teams in Quality Control, Analytical Development, Process Development, Manufacturing, and Quality to support analytical readiness for Capricor’s therapeutic programs. Collaboration This position works closely with multiple teams to ensure analytical controls meet the needs of Capricor’s research and manufacturing efforts. The scientist will contribute expertise to cross-functional projects and help maintain high standards for QC laboratory performance.

Apr 17, 2026
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Millennium Health LLC logo
Full-time|$93.6K/yr - $104K/yr|On-site|San Diego, California, United States

WORK SCHEDULEThis position operates on a 4x10 schedule, requiring three days of work between Tuesday and Friday, plus every Saturday, leading to a total of four days per week with ten hours each day. The work starts at 1:00 PM PST.Why Choose Millennium Health?Millennium Health LLC is a highly regarded accredited specialty laboratory with over ten years of experience in medication monitoring and drug testing services. We empower clinicians to monitor both the use and misuse of prescription medications and illicit substances, offering vital insights into patients’ recent substance use. Our commitment to quality and integrity is fundamental to our mission to support healthcare professionals and their patients effectively.GENERAL SUMMARYThe Clinical Laboratory Scientist will execute a variety of standardized urinalysis tests in our advanced toxicology lab, utilizing cutting-edge LC-MS-MS technology for the detection of prescription and illicit drugs. This role involves approving reports and patient results for ordering physicians.ESSENTIAL FUNCTIONSThe Clinical Laboratory Scientist will be accountable for the following functions while adhering to our quality standards:Conducting and reporting laboratory test results for all methods sanctioned by CAP, NY, and CLIA.Ensuring accuracy and timely delivery of test results.Entering testing data and performing standardized tests on urine samples using advanced LC-MS-MS technology.Evaluating result validity, maintaining detailed records, and generating comprehensive reports.Overseeing quality control and chromatographic data prior to releasing results to physicians.Adhering to established quality control protocols and assisting in preparing chromatographic data reports.Identifying, troubleshooting, documenting, and resolving issues with test results.Utilizing the Laboratory Occurrence Management (LOM) form for documentation purposes.Serving as a resource and trainer for laboratory technicians and assistants.Preparing and maintaining laboratory reagents and supplies, ensuring equipment is well-maintained and the lab is orderly.Following safe laboratory practices while participating in operational support activities to enhance testing capabilities.Overseeing the activities of clinical laboratory technicians and assistants as needed.

Jan 2, 2026
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Altos Labs logo
Full-time|On-site|San Diego, CA

Our MissionAt Altos Labs, we are dedicated to revitalizing cell health and resilience. Our innovative approach to cellular rejuvenation aims to reverse diseases, injuries, and the limitations that may arise throughout life.For more details, visit our website at altoslabs.com.Our ValuesWe embody a singular value at Altos: Everyone Owns Achieving Our Inspiring Mission.Diversity at AltosDiversity is essential for scientific innovation and inquiry. At Altos, we bring together exceptional scientists and industry leaders from diverse backgrounds to pursue a common goal. Our commitment to Belonging ensures that all employees feel valued for their unique perspectives, fostering a diverse and inclusive workplace.Your Contributions to AltosJoin us at Altos Labs, where we seek passionate, innovative, and collaborative individuals eager to leverage their expertise in advancing the understanding of cellular rejuvenation programming. This role encompasses contributions to foundational research, pre-clinical studies, and clinical-stage programs.Key ResponsibilitiesEngage in pioneering scientific research.Facilitate and supervise collaborations across multidisciplinary projects to accelerate pivotal research efforts.Investigate the mechanistic foundations of cellular programming for health and revitalization.Mentor graduate students.Develop project-specific experimental strategies, techniques, and protocols.Assist the Principal Investigator (PI) in training lab members, including scientists and technicians.Contribute to the writing and dissemination of research findings.Collaborate on research projects alongside the PI.

Feb 19, 2026
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Mulligan Funding logo
Full-time|On-site|San Diego, CA

Located in the vibrant city of San Diego, Mulligan Funding stands as a premier provider of working capital, offering up to $5 million to empower small and medium-sized businesses that drive our economy. Since our inception in 2008, we have embraced a culture of collaboration, innovation, and a steadfast commitment to customer satisfaction. As we navigate an exciting period of growth fueled by advanced technology and a personal touch, we are eager to welcome dynamic and results-driven professionals who are passionate about redefining possibilities and delivering value to our stakeholders.In the role of Staff Applied AI Scientist specializing in Decision Systems, you will architect the decision-making frameworks that drive our AI systems within real-world applications. This position transcends traditional research or engineering roles, placing you at the nexus of business strategy, risk assessment, and applied AI to ensure our decision-making systems are intelligent, well-calibrated, and aligned with economic goals.While engineering teams will implement these systems, you will be responsible for defining the decision intelligence that powers them. If you are enthusiastic about transforming business insights into structured, production-ready AI logic that has a direct impact on profitability, we invite you to explore this exciting opportunity.

Feb 26, 2026
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Experian logo
Full-time|Remote|San Diego

Join Experian's Innovation Lab as a Senior Data Scientist, where you will leverage your expertise to drive cutting-edge analytics and data-driven decision-making within our dynamic team. In this fully remote role, you will collaborate with cross-functional teams to develop innovative solutions that enhance business operations and customer experiences.

Mar 25, 2026
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Tendo logo
Full-time|On-site|San Diego, CA

Join us as a Principal Software Engineer, where you'll lead the creation of innovative healthcare software that significantly enhances the experiences of patients, clinicians, and caregivers. This role offers a unique chance to guide a software development team through the early phases of product creation while also contributing your own coding expertise and continuing your professional development.The ideal candidate will possess comprehensive full stack experience in developing SaaS and/or Cloud Native applications within regulated industries. You must have deep knowledge of technologies including but not limited to React, TypeScript, Go, Ent, gRPC, Twirp, and AWS services such as EventBridge and Aurora. A key aspect of this role will be mentoring and sharing knowledge with a rapidly growing team.If you thrive in an Agile environment where collaboration with product managers, designers, external partners, and fellow engineers is essential, this is the role for you. You will work together with stakeholders to build a high-quality, consumer-focused product from the ground up.About TendoMake a difference—be part of our mission-driven team!At Tendo, we are experiencing rapid growth and fostering a culture where teams and individuals can excel. We are proud to have been recognized by Forbes as one of the Top Startup Employers for 2024 and 2025. Our team, led by seasoned professionals, embodies our core values and seeks motivated individuals with diverse backgrounds to enhance the care journey for patients, clinicians, and caregivers through user-friendly software solutions.If you're passionate about working with cutting-edge technologies and want to help redefine the healthcare experience, we invite you to apply today!

Apr 29, 2024
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Art of Problem Solving logo
Full-time|On-site|San Diego, California, United States

At Art of Problem Solving (AoPS), we believe that data is a cornerstone of our innovative approach to designing, developing, and enhancing our educational products. We cater to a diverse community of students across the globe through our digital platforms that facilitate discovery, enrollment, learning, and sustained engagement. Our products generate comprehensive behavioral and operational data, which we leverage to make informed decisions that elevate student experiences. We are seeking a Senior Data Scientist to join us as an integral strategic partner within the Product team. This full-stack individual contributor role is ideal for someone who excels at defining key metrics, designing experiments, and addressing complex, high-stakes product inquiries. Your mission will be to enhance our product decision-making processes and bridge the gap between analytics and strategic direction. Collaborating closely with product leadership, engineers, and designers, you will help shape the direction of our products, assess trade-offs, and ensure we are crafting experiences that deliver genuine value to students and their families.

Feb 27, 2026
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AbbVie logo
Full-time|On-site|San Diego

Join AbbVie, a global biopharmaceutical company, as an Associate Scientist I/II in our Formulation & Process Development team in San Diego. You will play a pivotal role in the development of innovative drug formulations and manufacturing processes, contributing to our mission of improving patients' lives. This is an exciting opportunity for recent graduates or entry-level professionals eager to launch their careers in the biopharmaceutical industry.

Apr 30, 2026
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AbbVie Inc. logo
Full-time|On-site|San Diego

Join AbbVie as an Associate Scientist I/II in our Formulation & Process Development team in San Diego. In this dynamic role, you will contribute to the development of advanced drug formulations and processes. You will engage in collaborative research, utilizing your scientific expertise to solve complex challenges and support our mission of improving patient outcomes.

May 1, 2026
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Iambic Therapeutics logo
Full-time|On-site|San Diego HQ

We are on the lookout for exceptional scientists to join our Discovery Machine Learning team at Iambic Therapeutics. This position will play a pivotal role in utilizing cutting-edge machine learning techniques to enhance our drug discovery initiatives. You will collaborate with drug discovery teams focused on developing innovative therapeutics for a variety of conditions. Your work will center around our leading machine learning models, such as Enchant, our multimodal transformer model designed for predicting drug-target interactions and molecular properties. This opportunity is based at our headquarters in San Diego.

Feb 9, 2026
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Tendo logo
Full-time|On-site|San Diego, CA

We seek an innovative and passionate Senior Principal Software Engineer to lead the development of transformative healthcare software aimed at significantly enhancing the experiences of patients, clinicians, and caregivers. In this pivotal role, you will guide a talented team through the crucial early stages of product development while also contributing your own coding expertise and expanding your skill set.The ideal candidate boasts extensive full stack experience in crafting SaaS and/or Cloud Native solutions tailored for the regulated healthcare industry. You will possess significant knowledge in advanced technologies, including distributed microservice architecture, Go, Ent, gRPC, Twirp, and AWS services such as EventBridge and Aurora. Your ability to share insights and mentor developing team members will be essential for our growth.As a Senior Principal Software Engineer, you will thrive in an Agile, collaborative setting alongside product managers, designers, external partners, and fellow engineers, all working together to create high-quality, consumer-focused products from the ground up.About TendoJoin a mission-driven team making a real difference!At Tendo, we are rapidly expanding, fostering a culture that empowers teams and individuals to excel. Our commitment to a team-oriented environment has earned us recognition as one of Forbes’ Top Startup Employers for both 2024 and 2025. Guided by an experienced leadership team, we uphold our values and continuously seek motivated individuals from diverse backgrounds to enhance the care journey for all stakeholders by developing intuitive, user-friendly software.If you are excited to work with cutting-edge technologies and want to be part of a growing team that is reshaping the healthcare landscape, we invite you to apply today!

Apr 29, 2024
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Millennium Health LLC logo
Full-time|$115K/yr - $135K/yr|On-site|San Diego, California, United States

Millennium Health LLC is a highly regarded specialty laboratory with over a decade of expertise in medication monitoring and drug testing services. We empower healthcare professionals to effectively monitor both the use and misuse of prescription medications and illicit substances. Our testing solutions provide clinicians with objective insights into patients' recent drug usage, enhancing the effectiveness of treatment plans.We are seeking a Clinical Scientist who will take the lead in developing clinical LC-MS/MS assays. This role involves independently conducting original scientific research and creating innovative analytical technologies while managing project resources and timelines effectively.The responsibilities of this position include, but are not limited to: Acting as a technical leader to design, develop, and validate high-quality LC-MS/MS assays/products/technologies within established timelines. Providing formal and informal scientific mentoring to team members. Leveraging technical expertise to design experiments and independently contribute to multiple projects concurrently. Serving as a critical technical and scientific resource within the organization. Drafting, reviewing, and finalizing technical documentation essential for various stages of product development. Maintaining meticulous experimental records in compliance with company SOPs. Ensuring adherence to HIPAA, confidentiality, and compliance policies, procedures, and standards. Upholding administrative, physical, and technical cybersecurity controls. Consistent and reliable attendance is a must.

Dec 15, 2025
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Scismic logo
Full-time|$155K/yr - $240K/yr|On-site|San Diego, California

Scismic is proud to partner with a leading global consulting firm renowned for its collaborative and inclusive culture that nurtures creativity, growth, and innovation. With a dedicated team of over 1,000 professionals operating across 50 international markets, this organization collaborates with prestigious clients to tackle intricate business challenges spanning various industries. The company embraces a 'builder’s mindset,' empowering employees to devise innovative solutions, create a lasting impact, and advance their careers in a supportive environment.We are currently seeking a talented Senior Data Scientist who possesses extensive expertise in Natural Language Processing and Large Language Models to join our consulting practice. You will collaborate directly with Fortune 500 clients, leveraging cutting-edge AI technologies to address complex business challenges across diverse sectors.

Sep 5, 2025
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Iambic Therapeutics logo
Full-time|On-site|San Diego HQ

Job SummaryIambic Therapeutics is looking for an exceptional and driven Senior Associate Scientist to enhance our Chemistry team at our San Diego headquarters. This exciting position allows you to thrive in a vibrant, cross-disciplinary environment, where you will collaborate closely with medicinal chemists, biologists, DMPK scientists, computational chemists, machine learning experts, and software engineers. You will engage in every phase of the discovery process, from hit identification and lead optimization to candidate selection. This role is laboratory-focused and demands robust technical skills in organic synthesis, catalysis, and medicinal chemistry, alongside hands-on experience in the drug discovery process and a proven “drug hunter” mentality.Key ResponsibilitiesDesign, synthesize, purify, and characterize chemical compounds (10 mg–5 g scale) utilizing cutting-edge analytical techniques including LCMS, HPLC, and NMR, implementing both manual and automated parallel synthesis techniques.Identify and optimize reaction conditions through the use of screening kits and other efficient methodologies.Collaborate with the high-throughput experimentation team to guarantee successful execution of parallel chemistry experiments.Analyze biological and ADME-PK data using cheminformatics tools and contribute to data-driven discussions and strategic planning.Work alongside computational chemists to harness machine learning insights for the effective execution of the design–make–test cycle and platform development.Present findings to project teams and senior leadership, effectively communicating data, implications, and recommendations.QualificationsBS in Chemistry with 5+ years of experience in the pharmaceutical or biotechnology sector, or MS in Chemistry with 3+ years of relevant experience.Demonstrated expertise in multi-step organic synthesis, reaction optimization, Structure-Activity Relationship (SAR) analysis, and effective scientific presentation skills.Adeptness in a fast-paced, highly collaborative research atmosphere.Willingness to work onsite in San Diego.Preferred QualificationsExperience in high-throughput experimentation is advantageous.Familiarity with ADME-PK principles is a plus.5+ years of experience contributing to drug discovery projects is preferred.

Apr 2, 2026

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