Principal Scientist jobs in San Diego – Page 4 | RoboApply Jobs

Principal Scientist jobs in San Diego· Page 4

Results 61–69 of 69 for “Principal Scientist” in San Diego.

69 jobs found

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Altos Labs logo
Full-time|$150.4K/yr - $230K/yr|On-site|San Diego, CA; San Francisco Bay Area, CA

Our MissionAt Altos Labs, our mission is to rejuvenate cellular health and resilience, aiming to reverse diseases, injuries, and age-related disabilities.For further details, visit our website at altoslabs.com.Our ValueWe believe in a single core value: Everyone Owns Achieving Our Inspiring Mission.Diversity at AltosWe embrace diverse perspectives as essenti…

Feb 19, 2026
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Sony Interactive Entertainment logo
Principal, Vendor Insights & Operations

Sony Interactive Entertainment

Full-time|$193.6K/yr - $290.4K/yr|On-site|United States, San Diego, CA

Why Choose PlayStation?At PlayStation, we pride ourselves on being the ultimate destination for gaming and innovation. As a global leader in entertainment, we produce the PlayStation family of products and services, including the PlayStation®5, PlayStation®4, PlayStation®VR, PlayStation®Plus, and a range of acclaimed software titles from PlayStation Studios.We are committed to fostering an inclusive environment that empowers our employees and celebrates diversity. We invite those who share our passion for technology and play to explore our open positions and become part of our dynamic global team.The PlayStation brand is part of Sony Interactive Entertainment, a wholly-owned subsidiary of Sony Group Corporation.Position OverviewWe are seeking a Principal-level expert to enhance and drive enterprise vendor insights, optimize commercial strategies, and lead One Sony initiatives across Sony Interactive Entertainment and, where applicable, the broader Sony Group.The Principal, Vendor Insights & Operations will be instrumental in uncovering opportunities to maximize value from strategic vendor partnerships, focusing on contract consolidation, leveraging cross-OpCo synergies, and improving commercial results. This role will integrate vendor spending, utilization, contract structures, and performance metrics into executive-level insights that guide vendor strategy, investment choices, and negotiation tactics.As a senior individual contributor and trusted advisor, you will collaborate with vendor owners, procurement, finance, corporate planning, and Sony Group stakeholders to influence decision-making within complex, matrixed environments. The focus is on creating enterprise value and strategic alignment rather than routine vendor management.This position will lead enterprise-wide initiatives related to vendor value and insights, working closely with vendor management and performance teams that handle day-to-day vendor operations, SLA management, and operational performance oversight.Key Responsibilities:Drive One Sony initiatives and strategic vendor value.Identify and develop strategies for optimizing vendor partnerships.Analyze vendor performance and provide actionable insights to executive leadership.

Mar 13, 2026
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Craftwater logo
Full-time|Hybrid|San Diego

Your Journey with Us Begins Here:At Craftwater, we are not just another engineering firm; we are a team of passionate professionals dedicated to fostering significant environmental change. Our innovative and collaborative approach empowers our team to deliver actionable insights that make a real difference in resource planning and design. We pride ourselves on a flexible work environment that balances remote and in-office collaboration, embracing a California casual dress code—unless we’re meeting with clients or presenting our work. We maintain a light-hearted atmosphere while taking our responsibilities seriously, continuously pushing boundaries to provide our clients with the most impactful solutions. Join us as we embark on exciting new projects, fueled by creativity and camaraderie.

Jul 25, 2024
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Sony Interactive Entertainment logo
On-site|On-site|United States, San Diego, CA

Why Choose PlayStation?PlayStation is not only recognized as the premier destination for gaming but also as an exceptional workplace. We are proud to be a global leader in the entertainment industry, delivering the PlayStation family of products and services, including PlayStation®5, PlayStation®4, PlayStation®VR, PlayStation®Plus, and an array of award-winning titles from PlayStation Studios.At PlayStation, we are committed to fostering an inclusive environment that empowers our employees and celebrates diversity. We invite individuals with a passion for innovation, technology, and gaming to explore our open roles and join our expanding global team.The PlayStation brand operates under Sony Interactive Entertainment, a wholly-owned subsidiary of Sony Group Corporation.Principal Engineer, Developer Experience (DevEx)Location: Hybrid / Remote EligibleThe OpportunityAt PlayStation, we design the platforms and services that power some of the most iconic entertainment experiences globally. As our engineering organization continues to grow, Developer Experience (DevEx) has emerged as a pivotal focus area. We are dedicated to creating a cohesive, intelligent, and opinionated engineering ecosystem that allows teams to accelerate their workflows, build with confidence, and prioritize value creation.In this role, you will play a crucial part in shaping the future of engineering practices across PlayStation.

Feb 10, 2026
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Veracyte logo
Full-time|$150.2K/yr - $200K/yr|Remote|Remote ; San Diego, California, United States; South San Francisco, California, United States

At Veracyte, we provide thrilling career prospects for individuals eager to join a groundbreaking team dedicated to revolutionizing cancer care for patients worldwide. Being part of Veracyte allows our team members to create a significant impact on the lives of patients, while also fostering personal and professional growth within a mission-driven environment. This embodies what we refer to as the Veracyte way – a collaborative approach guided by our core values, ensuring clinicians have the insights necessary to assist patients in making life-altering decisions.Our Values:We Seek A Better Way: We innovate with courage, learn from our challenges, and remain resilient in our mission to transform cancer care.We Make It Happen: We act swiftly, uphold quality, and infuse enjoyment into our dedicated efforts.We Are Stronger Together: We collaborate transparently, seek understanding, and celebrate our achievements.We Care Deeply: We embrace our diversity, uphold integrity, and support one another.The Position:We are in search of a highly skilled and team-oriented Principal Test Engineer to spearhead the testing processes for applications at Veracyte. This role is critical in our endeavor to expand and develop innovative diagnostic solutions aimed at enhancing patient outcomes and reducing healthcare costs.The Principal Test Engineer is a senior, hands-on quality leader responsible for defining, executing, and continuously refining the software testing strategy within Veracyte's regulated environment. This position guarantees that all software products adhere to relevant quality, safety, and compliance standards while facilitating streamlined delivery processes. The Principal Test Engineer will serve as a subject-matter expert in verification and validation (V&V), test automation, risk-based testing, and regulatory compliance, offering technical guidance to junior testers and working closely with engineering, product, and quality teams.

Apr 1, 2026
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Shield AI logo
Full-time|On-site|San Diego, California

Join Shield AI as a Principal Electrical Engineer specializing in Power Electronics. In this pivotal role, you will lead the design and development of cutting-edge power electronic systems that drive our advanced technology solutions. Collaborate with a team of innovative engineers and contribute to projects that redefine the boundaries of technology.

Apr 8, 2026
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Stealth Fintech logo
Full-time|On-site|San Francisco, New York, or San Diego

Who We AreAt Stealth Fintech, we are driven by a vision to innovate ERP-native B2B payments. As a well-funded, early-stage startup operating in stealth mode, we are developing groundbreaking solutions that will revolutionize the way businesses manage financial transactions. If you are passionate about solving complex challenges and want to make a significant impact, we encourage you to reach out. Our founder-led team is dedicated to building a modern B2B payments infrastructure that leverages the information value of ERP systems, providing businesses with the ability to efficiently pay suppliers, card issuers, and reimburse employees globally with unparalleled speed, transparency, and control.About the RoleAs the Principal Product Manager for Digital Assets, you will spearhead the product strategy and execution of our innovative stablecoin-based payment infrastructure. This role sits at the crossroads of blockchain technology, enterprise finance, payments, compliance, and developer platforms, and you will play a pivotal role in guiding how global enterprises integrate digital assets into their existing ERP workflows. This is a high-impact position with direct influence over company strategy, external partnerships, and the future trajectory of programmable money within enterprise systems. Your efforts will help large corporations seamlessly adopt next-generation payment infrastructure, reaping the benefits of stablecoins while ensuring the trust, control, and reliability they expect.Your Key ResponsibilitiesDevelop and own a comprehensive product vision for stablecoin-powered global payments integrated directly into ERPs, ensuring alignment with enterprise objectives such as risk reduction, cost predictability, auditability, and system uptime.Establish the foundational architecture for an API-first, on-chain settlement network designed for multinational enterprises.Explore new product avenues related to:Stablecoin issuance and settlement mechanisms.On-/off-ramps and liquidity management.Cross-border treasury operations.

Jan 13, 2026
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Iambic Therapeutics logo
Senior Computational Chemist

Iambic Therapeutics

Full-time|On-site|San Diego HQ

Job SummaryIambic Therapeutics is looking for a talented and driven Computational Chemist to become a vital member of our Computational Sciences team at our San Diego headquarters. In this role, you will leverage advanced ligand and structure-based methodologies to propel our drug discovery initiatives. You will collaborate with multidisciplinary research teams focused on developing innovative therapeutics across various disease indications. This role involves close collaboration with machine learning scientists, medicinal chemists, and biologists, employing state-of-the-art Structure-Based Drug Design (SBDD) techniques throughout the phases of hit identification, lead optimization, and candidate selection. We seek an individual who possesses hands-on experience in computational chemistry, a proactive drug-hunter attitude, and a keen interest in co-folding applications. Your expertise will be critical in advancing our drug discovery goals.Key ResponsibilitiesUtilize a variety of ligand and structure-based strategies throughout hit identification, hit-to-lead, and lead optimization stages, including cheminformatics, pharmacophore modeling, docking, shape-based virtual screening, de novo molecular design, and molecular dynamics simulations.Drive design cycles by identifying structure-activity relationships and integrating computational predictions with bioactivity data.Collaborate with medicinal chemists to design, evaluate, and prioritize virtual libraries, providing actionable molecular design recommendations.Work alongside machine learning scientists to integrate SBDD methods with our proprietary transformer-based property prediction technology (Enchant).Enhance our proprietary protein-ligand co-folding technology (NeuralPLexer) to generate innovative and actionable structural hypotheses.Transform scientific inquiries into computational workflows, delivering significant and actionable results.Present findings to project teams, articulating methodologies, implications, and recommendations effectively.Develop, validate, and sustain computational workflows and tools for ongoing use.QualificationsRequired:PhD or equivalent degree in computational chemistry or a related field, with a minimum of 5 years of experience in an industry drug discovery environment.Proven experience in supporting active small molecule drug discovery programs.Comprehensive knowledge of ligand and structure-based methods.Expertise in computational chemistry software and tools.

Apr 30, 2026
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InnoPhase IoT logo
Full-time|On-site|San Diego, CA or San Jose, CA

About InnoPhase IoTAt InnoPhase IoT, we pride ourselves on our innovative culture that thrives on collaboration and creativity. Join a diverse team of talented professionals who are passionate about pushing the boundaries of technology in a vibrant startup environment. Here, you'll not only contribute to cutting-edge projects but also learn and grow through varied experiences—ensuring every day is unique and rewarding.We are on the lookout for individuals who are driven by excellence! If you excel in your field, why settle for less? Join us at InnoPhase IoT, where your skills can truly shine!As a Senior Staff/Principal Digital Design Engineer, you will collaborate with a dedicated team of design engineers to pioneer innovative SoC products focused on connectivity and communications. You will play a pivotal role in product definition and develop comprehensive performance and functionality specifications. Your expertise will facilitate the delivery of high-quality digital solutions aligned with the overarching product architecture, and you will support various other disciplines with deliverables such as Verilog stimulus files, test benches for device characterization, and test vectors for manufacturing.

Apr 15, 2025

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