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Associate Scientist - High-Throughput Protein Therapeutics

Xaira TherapeuticsSouth San Francisco, California, United States
On-site Full-time $101K/yr - $126K/yr

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Experience Level

Experience

Qualifications

Key ResponsibilitiesConduct high-throughput protein expression, purification, and characterization from various systems, including cell-free and mammalian platforms. Enhance team throughput and data quality by implementing innovative strategies for parallel protein processing. This includes optimizing expression and purification workflows, along with conducting quality control and functional assays for proteins intended for therapeutic development and in silico design. Maintain meticulous records and organization practices to ensure project efficiency. Possess the experience and flexibility to engage in upstream medium-scale expression and downstream purification processes. Perform analytical characterization of proteins to support therapeutic development.

About the job

Xaira Therapeutics is a biotech startup based in the San Francisco Bay Area, with additional offices in Seattle and London. The company applies artificial intelligence to drug discovery and development, building generative AI models to design protein and antibody therapeutics for challenging molecular targets. Xaira also develops foundational models in biology and disease to support target identification and patient stratification, aiming to improve outcomes in drug development.

Role overview

The High-Throughput team at Xaira is hiring an Associate Scientist to support the discovery and development of new protein therapeutics. This position focuses on designing and executing high-throughput expression, purification, and characterization campaigns. Collaboration is a key part of the role, with frequent interaction with robotics and data teams to combine biochemistry and automation. The goal is to turn computational protein designs into validated candidates for further study.

What you will do

  • Design and run high-throughput workflows for protein expression, purification, and characterization
  • Work closely with robotics and data teams to integrate automation and data analysis
  • Translate computational protein designs into physical candidates
  • Help drive the discovery and development of next-generation protein therapeutics

Who succeeds in this role

  • Works well independently and as part of cross-functional teams
  • Experience collaborating with discovery, process development, or analytical groups is helpful
  • Communicates data clearly to different audiences
  • Manages multiple tasks and adapts to shifting priorities
  • Brings a hands-on approach and a drive to advance drug discovery through scientific innovation

About Xaira Therapeutics

Xaira Therapeutics is a forward-thinking biotech startup at the forefront of utilizing artificial intelligence in drug discovery and development. Our mission is to innovate and streamline the process of creating effective therapeutics for complex diseases, ultimately improving patient outcomes globally.

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